HitPredict

Interactor 1: MDC1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)
Gene: MDC1

Interactor 2: SPF45 (Q96I25)
Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17)
Gene: RBM17

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30179224, 22990118
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2089 Hs			1 401
+	Hs
		1054314 MDC1_HUMAN (1-2089): 0: 665: 100.00		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		801307 KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53		SPF45_HUMAN (1-401): 4.66e-158: 452: 100.00
+	Hs
		801139 KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		641658 KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Hs
		1054673 SRRM2_HUMAN (133-1326): 2.15e-19: 98.4: 8.08		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		1054709 PRC2C_HUMAN (145-1944): 8.04e-16: 86.5: 8.07		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		1264818 TITIN_HUMAN (175-1895): 2.81e-32: 141: 8.72		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67
+	Hs
		641983 SRRM2_HUMAN (133-1326): 2.15e-19: 98.4: 8.08		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Hs
		1355616 SRRM2_HUMAN (133-1326): 2.15e-19: 98.4: 8.08		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67
+	Hs
		554269 MUC1_HUMAN (762-1525): 1.68e-11: 72: 18.23		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93