HitPredict

Interactor 1: MDC1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)
Gene: MDC1

Interactor 2: TE2IP (Q9NYB0)
Telomeric repeat-binding factor 2-interacting protein 1 (TERF2-interacting telomeric protein 1) (TRF2-interacting telomeric protein 1) (Dopamine receptor-interacting protein 5) (Repressor/activator protein 1 homolog) (RAP1 homolog) (hRap1)
Gene: TERF2IP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	34079125, 15383534
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BRCT_2~BRCT_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016604 - nuclear body
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2089 Hs			1 399
+	Hs
		1348409 NCOR2_HUMAN (149-1902): 1.48e-73: 276: 8.36		TE2IP_HUMAN (1-399): 0: 664: 100.00
+	Hs
		801429 KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53		TE2IP_HUMAN (1-399): 0: 664: 100.00
+	Hs
		1154079 NIPBL_HUMAN (869-1889): 2.17e-21: 104: 15.13		TE2IP_HUMAN (1-399): 0: 664: 100.00
+	Hs
		1348394 SRRM2_HUMAN (133-1326): 2.15e-19: 98.4: 8.08		TE2IP_HUMAN (1-399): 0: 664: 100.00
+	Hs
		1302929 MINT_HUMAN (159-1473): 1.72e-10: 68.9: 10.33		TE2IP_HUMAN (1-399): 0: 664: 100.00