HitPredict

Interactor 1: EPN4 (Q14677)
Clathrin interactor 1 (Clathrin-interacting protein localized in the trans-Golgi region) (Clint) (Enthoprotin) (Epsin-4) (Epsin-related protein) (EpsinR)
Gene: CLINT1

Interactor 2: GGA2 (Q9UJY4)
ADP-ribosylation factor-binding protein GGA2 (Gamma-adaptin-related protein 2) (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear)
Gene: GGA2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.698

Property	Details
Experiments	12429846, 28514442, 12213833, 33961781
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 625 Hs			1 613
+	Hs
		1057133 EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00		GGA1_HUMAN (19-612): 1.68e-159: 473: 44.67
+	Hs
		212629 EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00		AP1G1_HUMAN (44-610): 7.48e-109: 347: 17.44
+	Sc
		755535 ENT3_YEAST (2-385): 3.45e-84: 271: 24.94		GGA2_YEAST (15-607): 3.14e-107: 336: 19.31
+	Hs
		1057124 EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00		GGA3_HUMAN (328-611): 1.6e-47: 179: 32.33
+	Sc
		755540 ENT5_YEAST (2-381): 2.25e-43: 162: 18.75		GGA2_YEAST (15-607): 3.14e-107: 336: 19.31
+	At
		1195469 EPN1_ARATH (7-421): 1.05e-66: 229: 21.81		AP1G1_ARATH (44-605): 2e-74: 256: 15.08
+	Rn
		291396 EPN1_RAT (8-529): 1.01e-68: 235: 24.63		Q8R525_RAT (389-606): 4.53e-51: 180: 23.68