HitPredict

Interactor 1: SMC1A (Q14683)
Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8)
Gene: SMC1A

Interactor 2: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	29568061, unassigned1655
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0046982 - protein heterodimerization activity GO:0051301 - cell division
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1233 Hs			1 451
+	Hs
		1057372 SMC1A_HUMAN (1-1233): 1.94e-128: 427: 100.00		TBA1C_HUMAN (1-451): 0: 726: 98.00
+	Hs
		933205 SMC1A_HUMAN (1-1233): 1.94e-128: 427: 100.00		TBA1B_HUMAN (1-440): 0: 715: 99.55
+	Hs
		933814 SMC1A_HUMAN (1-1233): 1.94e-128: 427: 100.00		TBB4B_HUMAN (1-437): 0: 693: 40.50
+	Hs
		311571 SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57		TBA1A_HUMAN (1-440): 0: 713: 100.00
+	Hs
		933392 SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00		TBA1B_HUMAN (1-440): 0: 715: 99.55
+	Hs
		1175251 SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00		TBA1A_HUMAN (1-440): 0: 713: 100.00
+	Hs
		428501 SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00		TBB5_HUMAN (1-439): 0: 695: 40.77