Protein: HPSE
Heparanase (EC 3.2.1.166) (Endo-glucoronidase) (Heparanase-1) (Hpa1) [Cleaved into: Heparanase 8 kDa subunit; Heparanase 50 kDa subunit]

Gene: HPSE
Organism: Homo sapiens
Interactions: 46
UniProt ID: Q9Y251

Gene Ontology (top 5):
GO:0004566 - beta-glucuronidase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1030898

SG2A2
Mammaglobin-A

2

1

High-throughput

0.628

High

1262172

DNJA4
DnaJ homolog subfamily A member 4

2

3

High-throughput

0.574

High

269369

SG2A1
Mammaglobin-B

1

1

High-throughput

0.536

High

636447

DNJB1
DnaJ homolog subfamily B member 1

1

3

High-throughput

0.536

High

681652

DNJA1
DnaJ homolog subfamily A member 1

1

3

High-throughput

0.536

High

685117

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.536

High

714470

HSP74
Heat shock 70 kDa protein 4

1

1

High-throughput

0.536

High

1267787

HS105
Heat shock protein 105 kDa

1

1

High-throughput

0.536

High

1335242

RC3H2
Roquin-2

1

1

High-throughput

0.536

High

1274482

H2B1H
Histone H2B type 1-H

1

1

High-throughput

0.515

High

124651

CLIC1
Chloride intracellular channel protein 1

1

0

High-throughput

0.513

High

384034

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

0

High-throughput

0.513

High

486352

CCL3
C-C motif chemokine 3

1

0

High-throughput

0.513

High

557296

PGFRA
Platelet-derived growth factor receptor alpha

1

0

High-throughput

0.513

High

824546

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.513

High

832061

PSB3
Proteasome subunit beta type-3

1

0

High-throughput

0.513

High

871834

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.513

High

875919

MFAP4
Microfibril-associated glycoprotein 4

1

0

High-throughput

0.513

High

1262461

CA054
Uncharacterized protein C1orf54

1

0

High-throughput

0.513

High

1271379

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

1315283

C1QT7
Complement C1q tumor necrosis factor-related protein 7

1

0

High-throughput

0.513

High

1356697

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.513

High

1377018

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.513

High

1377019

FBX7
F-box only protein 7

1

0

High-throughput

0.513

High

243673

DNJA2
DnaJ homolog subfamily A member 2

1

3

High-throughput

0.489

High

309171

KI20A
Kinesin-like protein KIF20A

1

1

High-throughput

0.479

High

1305148

DNJC7
DnaJ homolog subfamily C member 7

1

2

High-throughput

0.479

High

1357477

CHIP
E3 ubiquitin-protein ligase CHIP

1

2

High-throughput

0.479

High

1066893

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1377017

HPSE
Heparanase

1

0

Small-scale

0.458

High

59500

A4D110
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.445

High

110674

H3BS86
RING-type E3 ubiquitin transferase

1

2

High-throughput

0.445

High

111527

K7EIH8
DnaJ heat shock protein family

1

2

High-throughput

0.445

High

1034563

OS9
Protein OS-9

2

0

High-throughput

0.328

High

303734

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

324127

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low

686779

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.279

Low

882837

STX17
Syntaxin-17

1

0

High-throughput

0.279

Low

1114265

TBB8
Tubulin beta-8 chain

1

0

High-throughput

0.279

Low

1240868

RETR2
Reticulophagy regulator 2

1

0

High-throughput

0.279

Low

1300410

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.279

Low

1308567

NIPS1
Protein NipSnap homolog 1

1

0

High-throughput

0.279

Low

1355241

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.279

Low

1356247

FBX2
F-box only protein 2

1

0

High-throughput

0.279

Low

1123478

H90B2
Putative heat shock protein HSP 90-beta 2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024