HitPredict

Interactor 1: KCNB1 (Q14721)
Potassium voltage-gated channel subfamily B member 1 (Delayed rectifier potassium channel 1) (DRK1) (h-DRK1) (Voltage-gated potassium channel subunit Kv2.1)
Gene: KCNB1

Interactor 2: KCNG4 (Q8TDN1)
Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4)
Gene: KCNG4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.821

The method score is based on:

Property Details
Experiments 19074135, 26242757
Identification Methods two hybrid, fluorescent resonance energy transfer, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BTB_2~BTB_2, Ion_trans~Ion_trans
Common GO terms GO:0005251 - delayed rectifier potassium channel activity
GO:0005886 - plasma membrane
GO:0008076 - voltage-gated potassium channel complex
GO:0044325 - transmembrane transporter binding
GO:0051260 - protein homooligomerization
and 1 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024