HitPredict

Interactor 1: KCNB1 (Q14721)
Potassium voltage-gated channel subfamily B member 1 (Delayed rectifier potassium channel 1) (DRK1) (h-DRK1) (Voltage-gated potassium channel subunit Kv2.1)
Gene: KCNB1

Interactor 2: KCNS3 (Q9BQ31)
Potassium voltage-gated channel subfamily S member 3 (Delayed-rectifier K(+) channel alpha subunit 3) (Voltage-gated potassium channel subunit Kv9.3)
Gene: KCNS3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9362476
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BTB_2~BTB_2, Ion_trans~Ion_trans
Common GO terms	GO:0005251 - delayed rectifier potassium channel activity GO:0005886 - plasma membrane GO:0008076 - voltage-gated potassium channel complex GO:0051260 - protein homooligomerization GO:0071805 - potassium ion transmembrane transport
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 858 Hs			1 491
+	Hs
		1058636 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNV1_HUMAN (19-452): 8.19e-159: 461: 42.48
+	Hs
		1058645 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNB2_HUMAN (9-490): 2.36e-143: 435: 41.19
+	Hs
		1058633 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNB1_HUMAN (9-490): 5.18e-143: 433: 41.19
+	Mm
		61654 KCNB1_MOUSE (1-858): 0: 712: 93.71		KCNB2_MOUSE (9-490): 1.47e-144: 438: 41.39
+	Hs
		1161871 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNV1_HUMAN (19-452): 8.19e-159: 461: 42.48
+	Hs
		1273152 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNB2_HUMAN (9-490): 2.36e-143: 435: 41.19
+	Hs
		1273155 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNS3_HUMAN (1-491): 2.46e-146: 429: 100.00
+	Hs
		1058643 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNG4_HUMAN (3-469): 1e-103: 321: 32.92
+	Hs
		1058649 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNG1_HUMAN (8-429): 5.58e-103: 319: 36.18
+	Hs
		1058644 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNV2_HUMAN (5-431): 1.29e-101: 316: 38.27
+	Hs
		1273157 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNF1_HUMAN (7-489): 2.36e-119: 360: 32.45
+	Hs
		1058642 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNG3_HUMAN (17-417): 1.53e-78: 253: 35.14
+	Hs
		1255150 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNG4_HUMAN (3-469): 1e-103: 321: 32.92
+	Hs
		1273162 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNG1_HUMAN (8-429): 5.58e-103: 319: 36.18
+	Hs
		1251106 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNG3_HUMAN (17-417): 1.53e-78: 253: 35.14
+	Hs
		569033 KCNA6_HUMAN (2-429): 3.18e-167: 497: 32.31		KCNA3_HUMAN (13-486): 4.64e-109: 337: 27.94