Protein: OSB11
Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11)

Gene: OSB11, OSBPL11
Organism: Homo sapiens
Interactions: 148
UniProt ID: Q9BXB4

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0006869 - lipid transport
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1403104

OSBL9
Oxysterol-binding protein-related protein 9

4

12

Small-scale

0.898

High

976528

RB11A
Ras-related protein Rab-11A

3

5

High-throughput

0.827

High

631448

RAB5A
Ras-related protein Rab-5A

3

12

High-throughput

0.817

High

956468

RAB2A
Ras-related protein Rab-2A

2

7

High-throughput

0.737

High

333169

VAPB
Vesicle-associated membrane protein-associated protein B/C

6

20

Small-scale

0.732

High

1416729

VAPA
Vesicle-associated membrane protein-associated protein A

5

20

High-throughput

0.720

High

1416712

OSB10
Oxysterol-binding protein-related protein 10

1

13

High-throughput

0.691

High

727946

DNJA1
DnaJ homolog subfamily A member 1

3

2

High-throughput

0.667

High

728413

AKT1
RAC-alpha serine/threonine-protein kinase

1

2

Small-scale

0.647

High

488263

LOX5
Polyunsaturated fatty acid 5-lipoxygenase

3

0

High-throughput

0.634

High

126778

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

375902

RASK
GTPase KRas

1

13

High-throughput

0.618

High

412555

NTRK1
High affinity nerve growth factor receptor

1

17

High-throughput

0.618

High

463740

LYN
Tyrosine-protein kinase Lyn

1

2

Small-scale

0.618

High

465636

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.618

High

541667

FGFR1
Fibroblast growth factor receptor 1

1

15

High-throughput

0.618

High

581264

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

630621

RAB3B
Ras-related protein Rab-3B

1

5

High-throughput

0.618

High

901539

RAB7A
Ras-related protein Rab-7a

1

15

High-throughput

0.618

High

902040

RAB9A
Ras-related protein Rab-9A

1

15

High-throughput

0.618

High

945085

RAB25
Ras-related protein Rab-25

1

5

High-throughput

0.618

High

962439

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

975214

ARF6
ADP-ribosylation factor 6

1

2

High-throughput

0.618

High

978266

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

988672

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1015734

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

1145087

RAB35
Ras-related protein Rab-35

1

6

High-throughput

0.618

High

423077

A4
Amyloid-beta precursor protein

2

2

High-throughput

0.602

High

242801

PRKN
E3 ubiquitin-protein ligase parkin

2

7

High-throughput

0.584

High

603356

KPCA
Protein kinase C alpha type

1

2

High-throughput

0.575

High

1051047

FAK1
Focal adhesion kinase 1

1

11

High-throughput

0.575

High

1416721

SAR1A
Small COPII coat GTPase SAR1A

1

9

High-throughput

0.575

High

1412962

FUZZY
Protein fuzzy homolog

2

3

High-throughput

0.558

High

601427

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.553

High

630954

RAB4A
Ras-related protein Rab-4A

1

7

High-throughput

0.553

High

901016

RAB5C
Ras-related protein Rab-5C

1

12

High-throughput

0.553

High

1151852

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.553

High

1324070

RHG24
Rho GTPase-activating protein 24

1

3

High-throughput

0.553

High

135694

DNM1L
Dynamin-1-like protein

1

0

High-throughput

0.546

High

299574

TRIO
Triple functional domain protein

1

0

High-throughput

0.546

High

912804

AGFG1
Arf-GAP domain and FG repeat-containing protein 1

1

0

High-throughput

0.546

High

555838

MYL4
Myosin light chain 4

1

3

High-throughput

0.536

High

931093

HSP72
Heat shock-related 70 kDa protein 2

1

3

High-throughput

0.536

High

1313692

IFT20
Intraflagellar transport protein 20 homolog

1

1

High-throughput

0.536

High

872706

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.513

High

1101890

SKP2
S-phase kinase-associated protein 2

1

0

High-throughput

0.513

High

1291182

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.513

High

1340741

TPC2
Two pore channel protein 2

1

0

High-throughput

0.513

High

1416713

DUS16
Dual specificity protein phosphatase 16

1

0

High-throughput

0.513

High

1235388

KLH10
Kelch-like protein 10

1

4

High-throughput

0.489

High

1391369

CFA36
Cilia- and flagella-associated protein 36

1

1

High-throughput

0.489

High

1416739

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

4

High-throughput

0.489

High

791683

SYUA
Alpha-synuclein

1

3

High-throughput

0.481

High

954407

SNP25
Synaptosomal-associated protein 25

1

8

Small-scale

0.481

High

218721

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

226188

STX6
Syntaxin-6

1

2

High-throughput

0.479

High

291522

NU155
Nuclear pore complex protein Nup155

1

4

High-throughput

0.479

High

414547

P53
Cellular tumor antigen p53

1

2

High-throughput

0.479

High

418408

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

2

High-throughput

0.479

High

540654

LAMP1
Lysosome-associated membrane glycoprotein 1

1

7

High-throughput

0.479

High

560506

IFM1
Interferon-induced transmembrane protein 1

1

4

High-throughput

0.479

High

562372

LAMP2
Lysosome-associated membrane glycoprotein 2

1

7

High-throughput

0.479

High

589597

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

611323

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

4

High-throughput

0.479

High

696409

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

699071

CALX
Calnexin

1

2

High-throughput

0.479

High

715751

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

769079

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.479

High

895026

EMD
Emerin

1

1

High-throughput

0.479

High

951399

SC61B
Protein transport protein Sec61 subunit beta

1

4

High-throughput

0.479

High

1031528

IFM3
Interferon-induced transmembrane protein 3

1

4

High-throughput

0.479

High

1058630

CKAP4
Cytoskeleton-associated protein 4

1

4

High-throughput

0.479

High

1087266

STX4
Syntaxin-4

1

9

High-throughput

0.479

High

1125636

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

3

High-throughput

0.479

High

1149980

TERF2
Telomeric repeat-binding factor 2

1

1

High-throughput

0.479

High

1233458

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.479

High

1368945

GOGA1
Golgin subfamily A member 1

1

1

High-throughput

0.479

High

1383047

LRC59
Leucine-rich repeat-containing protein 59

1

2

High-throughput

0.479

High

1404182

SEC62
Translocation protein SEC62

1

5

High-throughput

0.479

High

1414438

DERL1
Derlin-1

1

1

High-throughput

0.479

High

1416715

WWTR1
WW domain-containing transcription regulator protein 1

1

2

High-throughput

0.479

High

1416718

TMT1A
Thiol S-methyltransferase TMT1A

1

3

High-throughput

0.479

High

1416723

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.479

High

1416727

ELOV5
Very long chain fatty acid elongase 5

1

2

High-throughput

0.479

High

1416730

TM216
Transmembrane protein 216

1

2

High-throughput

0.479

High

1416731

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

1416735

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1416736

ANC2
Anaphase-promoting complex subunit 2

1

4

High-throughput

0.479

High

1416737

LAMP3
Lysosome-associated membrane glycoprotein 3

1

7

High-throughput

0.479

High

1416738

KLH20
Kelch-like protein 20

1

3

High-throughput

0.479

High

1106691

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

1156197

ZYX
Zyxin

1

0

High-throughput

0.458

High

1289595

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

162120

ACOT8
Acyl-coenzyme A thioesterase 8

1

1

High-throughput

0.445

High

1062845

QOR
Quinone oxidoreductase

1

1

High-throughput

0.445

High

1164011

HCDH
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

1

2

High-throughput

0.445

High

1290291

KBTB6
Kelch repeat and BTB domain-containing protein 6

1

6

Small-scale

0.445

High

1391493

BSCL2
Seipin

1

1

High-throughput

0.445

High

1416726

RBM12
RNA-binding protein 12

1

2

High-throughput

0.445

High

1416728

LMCD1
LIM and cysteine-rich domains protein 1

1

2

High-throughput

0.445

High

1416740

S23IP
SEC23-interacting protein

1

4

High-throughput

0.445

High

189811

STX7
Syntaxin-7

1

6

High-throughput

0.437

High

1027168

REEP5
Receptor expression-enhancing protein 5

1

3

High-throughput

0.437

High

1111687

STIM1
Stromal interaction molecule 1

1

1

High-throughput

0.437

High

1255375

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.437

High

1293132

TMM17
Transmembrane protein 17

1

2

High-throughput

0.437

High

1322971

CXD3
Gap junction delta-3 protein

1

2

High-throughput

0.437

High

1416717

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

3

High-throughput

0.437

High

176708

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.426

High

255866

USO1
General vesicular transport factor p115

1

0

High-throughput

0.426

High

334634

LYPA2
Acyl-protein thioesterase 2

1

0

High-throughput

0.426

High

564850

NCAM1
Neural cell adhesion molecule 1

1

0

High-throughput

0.426

High

854924

RECQ1
ATP-dependent DNA helicase Q1

1

0

High-throughput

0.426

High

877378

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.426

High

884563

SYAC
Alanine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

945524

GSDMD
Gasdermin-D

1

0

High-throughput

0.426

High

1009881

NUCB2
Nucleobindin-2

1

0

High-throughput

0.426

High

1036117

MMSA
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial

1

0

High-throughput

0.426

High

1198206

PDCD4
Programmed cell death protein 4

1

0

High-throughput

0.426

High

1309992

NXP20
Protein NOXP20

1

0

High-throughput

0.426

High

1365175

NDRG1
Protein NDRG1

1

0

High-throughput

0.426

High

1403692

NIBA2
Protein Niban 2

1

0

High-throughput

0.426

High

1407339

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.426

High

1416714

FTO
Alpha-ketoglutarate-dependent dioxygenase FTO

1

0

High-throughput

0.426

High

1416716

I2BPL
Probable E3 ubiquitin-protein ligase IRF2BPL

1

0

High-throughput

0.426

High

1416720

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

1

0

High-throughput

0.426

High

1416722

SIAS
N-acetylneuraminate-9-phosphate synthase

1

0

High-throughput

0.426

High

1416724

PHP14
14 kDa phosphohistidine phosphatase

1

0

High-throughput

0.426

High

1416725

ATG3
Ubiquitin-like-conjugating enzyme ATG3

1

0

High-throughput

0.426

High

1416732

SAE1
SUMO-activating enzyme subunit 1

1

0

High-throughput

0.426

High

1416733

SAE2
SUMO-activating enzyme subunit 2

1

0

High-throughput

0.426

High

97013

E9PK12
Fuzzy planar cell polarity protein

1

3

High-throughput

0.407

High

847440

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

1

1

High-throughput

0.407

High

1152852

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

3

High-throughput

0.407

High

1416734

PEF1
Peflin

1

1

High-throughput

0.407

High

1416640

PLVAP
Plasmalemma vesicle-associated protein

3

0

High-throughput

0.347

High

159260

ABLM1
Actin-binding LIM protein 1

1

0

High-throughput

0.232

Low

458709

SAP
Prosaposin

1

0

High-throughput

0.232

Low

571158

CD99
CD99 antigen

1

0

High-throughput

0.232

Low

603806

ITA2
Integrin alpha-2

1

0

High-throughput

0.232

Low

728884

3HIDH
3-hydroxyisobutyrate dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

892309

SPS1
Selenide, water dikinase 1

1

0

High-throughput

0.232

Low

963974

NPC2
NPC intracellular cholesterol transporter 2

1

0

High-throughput

0.232

Low

1216345

NT5D1
5'-nucleotidase domain-containing protein 1

1

0

High-throughput

0.232

Low

1362064

LZIC
Protein LZIC

1

0

High-throughput

0.232

Low

1405988

C10
Protein C10

1

0

High-throughput

0.232

Low

1416526

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.232

Low

1416719

GLOD4
Glyoxalase domain-containing protein 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025