HitPredict

Interactor 1: CBX2 (Q14781)
Chromobox protein homolog 2
Gene: CBX2

Interactor 2: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.578

Property	Details
Experiments	20850016, 21047797
Identification Methods	unspecified method, x-ray crystallography
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 532 Hs			1 136
+	Hs
		934768 CBX2_HUMAN (1-532): 6.32e-156: 457: 100.00		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		952341 CBX2_HUMAN (1-532): 6.32e-156: 457: 100.00		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		1059165 CBX2_HUMAN (1-532): 6.32e-156: 457: 100.00		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Mm
		675496 CBX2_MOUSE (1-532): 1.26e-145: 430: 81.84		H33_MOUSE (1-136): 4.53e-61: 185: 93.38
+	Hs
		828230 CBX2_HUMAN (1-532): 6.32e-156: 457: 100.00		CENPA_HUMAN (9-133): 3.54e-44: 142: 49.24
+	Mm
		223226 CBX4_MOUSE (3-522): 1.1e-116: 357: 22.28		H33_MOUSE (1-136): 4.53e-61: 185: 93.38
+	Hs
		123231 CBX4_HUMAN (3-522): 6.17e-110: 340: 21.89		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		123254 CBX4_HUMAN (3-522): 6.17e-110: 340: 21.89		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		123236 CBX4_HUMAN (3-522): 6.17e-110: 340: 21.89		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		123269 CBX4_HUMAN (3-522): 6.17e-110: 340: 21.89		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		111555 CBX4_HUMAN (3-522): 6.17e-110: 340: 21.89		K7EK07_HUMAN (1-132): 3.48e-59: 180: 93.18
+	Hs
		935387 CDYL_HUMAN (2-297): 1.28e-60: 211: 21.63		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		1086356 CDYL_HUMAN (2-297): 1.28e-60: 211: 21.63		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		952709 CDYL_HUMAN (2-297): 1.28e-60: 211: 21.63		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		935156 MPP8_HUMAN (7-397): 6.88e-47: 177: 17.54		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Dm
		356104 Q9VCU6_DROME (9-253): 3.96e-52: 179: 20.64		H3_DROME (1-136): 1.34e-60: 184: 96.32
+	Hs
		934987 CDYL2_HUMAN (10-297): 9.15e-48: 175: 17.81		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		952579 MPP8_HUMAN (7-397): 6.88e-47: 177: 17.54		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		1086221 CDYL2_HUMAN (10-297): 9.15e-48: 175: 17.81		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Dm
		356085 RHINO_DROME (1-315): 3.1e-47: 171: 16.35		H3_DROME (1-136): 1.34e-60: 184: 96.32