Protein: MED13
Mediator of RNA polymerase II transcription subunit 13 (Activator-recruited cofactor 250 kDa component) (ARC250) (Mediator complex subunit 13) (Thyroid hormone receptor-associated protein 1) (Thyroid hormone receptor-associated protein complex 240 kDa component) (Trap240) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP250)

Gene: MED13
Organism: Homo sapiens
Interactions: 77
UniProt ID: Q9UHV7

Gene Ontology (top 5):
GO:0003712 - transcription coregulator activity
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1174786

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

2

1

High-throughput

0.776

High

826370

CDK8
Cyclin-dependent kinase 8

17

7

Small-scale

0.763

High

48742

MED19
Mediator of RNA polymerase II transcription subunit 19

10

1

Small-scale

0.756

High

1076213

MED1
Mediator of RNA polymerase II transcription subunit 1

9

4

Small-scale

0.752

High

1312308

MED10
Mediator of RNA polymerase II transcription subunit 10

8

1

Small-scale

0.749

High

1328957

MED28
Mediator of RNA polymerase II transcription subunit 28

7

1

Small-scale

0.746

High

1314888

CDK19
Cyclin-dependent kinase 19

7

7

Small-scale

0.745

High

1342940

MED4
Mediator of RNA polymerase II transcription subunit 4

6

2

Small-scale

0.737

High

1312771

MED18
Mediator of RNA polymerase II transcription subunit 18

6

2

Small-scale

0.736

High

1347851

MED29
Mediator of RNA polymerase II transcription subunit 29

6

1

Small-scale

0.736

High

206659

MED7
Mediator of RNA polymerase II transcription subunit 7

6

2

Small-scale

0.735

High

1274360

MED12
Mediator of RNA polymerase II transcription subunit 12

6

4

High-throughput

0.732

High

1347149

MED9
Mediator of RNA polymerase II transcription subunit 9

6

1

Small-scale

0.730

High

1037112

MED21
Mediator of RNA polymerase II transcription subunit 21

5

1

High-throughput

0.723

High

624525

CCNC
Cyclin-C

5

5

High-throughput

0.712

High

1355586

MED23
Mediator of RNA polymerase II transcription subunit 23

5

3

Small-scale

0.711

High

313475

MED26
Mediator of RNA polymerase II transcription subunit 26

4

1

Small-scale

0.694

High

1281456

FBXW7
F-box/WD repeat-containing protein 7

4

1

Small-scale

0.692

High

1355588

MED31
Mediator of RNA polymerase II transcription subunit 31

3

2

High-throughput

0.671

High

1061335

NR1I3
Nuclear receptor subfamily 1 group I member 3

3

8

High-throughput

0.667

High

225433

MED14
Mediator of RNA polymerase II transcription subunit 14

3

4

High-throughput

0.662

High

265373

MED24
Mediator of RNA polymerase II transcription subunit 24

3

1

High-throughput

0.662

High

1074735

MED22
Mediator of RNA polymerase II transcription subunit 22

3

1

High-throughput

0.662

High

1158932

MED27
Mediator of RNA polymerase II transcription subunit 27

3

1

High-throughput

0.662

High

1293709

MED30
Mediator of RNA polymerase II transcription subunit 30

3

2

Small-scale

0.662

High

1334010

MED20
Mediator of RNA polymerase II transcription subunit 20

3

1

High-throughput

0.662

High

1346444

MED17
Mediator of RNA polymerase II transcription subunit 17

3

2

High-throughput

0.662

High

1349549

MED11
Mediator of RNA polymerase II transcription subunit 11

3

2

High-throughput

0.662

High

1301099

MED15
Mediator of RNA polymerase II transcription subunit 15

3

2

Small-scale

0.650

High

370653

ESR1
Estrogen receptor

3

7

Small-scale

0.641

High

738997

SRBP1
Sterol regulatory element-binding protein 1

3

0

Small-scale

0.613

High

270539

MED6
Mediator of RNA polymerase II transcription subunit 6

2

2

High-throughput

0.601

High

1206166

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

2

5

High-throughput

0.601

High

1291853

MED8
Mediator of RNA polymerase II transcription subunit 8

2

2

High-throughput

0.601

High

1355587

MED16
Mediator of RNA polymerase II transcription subunit 16

2

2

High-throughput

0.601

High

509992

VDR
Vitamin D3 receptor

2

3

Small-scale

0.584

High

1174976

MED25
Mediator of RNA polymerase II transcription subunit 25

2

0

Small-scale

0.576

High

1269865

ESR2
Estrogen receptor beta

2

7

High-throughput

0.571

High

1085709

HIF1A
Hypoxia-inducible factor 1-alpha

1

2

Small-scale

0.536

High

1160905

FXL19
F-box/LRR-repeat protein 19

1

1

High-throughput

0.536

High

417447

ENOA
Alpha-enolase

1

0

High-throughput

0.518

High

1295502

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.518

High

1355585

MED13
Mediator of RNA polymerase II transcription subunit 13

1

1

High-throughput

0.515

High

245063

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.479

High

266442

TAD2A
Transcriptional adapter 2-alpha

1

1

High-throughput

0.479

High

487821

ANDR
Androgen receptor

1

7

High-throughput

0.479

High

583620

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

583835

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

1

High-throughput

0.479

High

625086

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

High-throughput

0.479

High

677047

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

High-throughput

0.479

High

738908

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

1

High-throughput

0.479

High

854392

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

1

High-throughput

0.479

High

913977

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

1

High-throughput

0.479

High

944472

PRKDC
DNA-dependent protein kinase catalytic subunit

1

1

Small-scale

0.479

High

1019162

TP53B
TP53-binding protein 1

1

2

High-throughput

0.479

High

1132757

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

2

High-throughput

0.479

High

1154083

NIPBL
Nipped-B-like protein

1

1

High-throughput

0.479

High

1173779

ACD11
Acyl-CoA dehydrogenase family member 11

1

1

High-throughput

0.479

High

1221388

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

1

High-throughput

0.479

High

1355590

SCC4
MAU2 chromatid cohesion factor homolog

1

1

High-throughput

0.479

High

266509

SUPT3
Transcription initiation protein SPT3 homolog

1

0

Small-scale

0.458

High

1076300

TRIP4
Activating signal cointegrator 1

1

0

High-throughput

0.458

High

1242683

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

0

Small-scale

0.458

High

1299703

QKI
KH domain-containing RNA-binding protein QKI

1

0

High-throughput

0.458

High

1332194

STN1
CST complex subunit STN1

1

0

High-throughput

0.458

High

73048

B4DUB1
cDNA FLJ50029, highly similar to Cell division cycle 2-like protein kinase 6

1

7

High-throughput

0.445

High

91317

E5RFK5
Cyclin-C

1

5

High-throughput

0.445

High

1271463

KAT2A
Histone acetyltransferase KAT2A

1

3

Small-scale

0.445

High

1301414

NUDC1
NudC domain-containing protein 1

1

1

High-throughput

0.445

High

1355589

TRRAP
Transformation/transcription domain-associated protein

1

1

Small-scale

0.445

High

329055

TCL1B
T-cell leukemia/lymphoma protein 1B

3

0

High-throughput

0.347

High

1205334

PTH
Peptidyl-tRNA hydrolase

1

0

High-throughput

0.279

Low

256835

T22D2
TSC22 domain family protein 2

1

0

Small-scale

0.251

Low

943534

TCPB
T-complex protein 1 subunit beta

1

0

Small-scale

0.249

Low

1344812

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.238

Low

484495

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024