HitPredict

Interactor 1: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28977666
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1912 Hs			1 136
+	Hs
		934770 CHD4_HUMAN (1-1912): 0: 1719: 100.00		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		1059646 CHD4_HUMAN (1-1912): 0: 1719: 100.00		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		952343 CHD4_HUMAN (1-1912): 0: 1719: 100.00		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		1059677 CHD4_HUMAN (1-1912): 0: 1719: 100.00		H3C_HUMAN (1-136): 8.83e-59: 179: 94.12
+	Hs
		934705 CHD3_HUMAN (23-1905): 0: 1595: 66.89		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		952302 CHD3_HUMAN (23-1905): 0: 1595: 66.89		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Mm
		56901 CHD5_MOUSE (89-1912): 0: 1588: 70.15		H33_MOUSE (1-136): 1.59e-61: 186: 97.06
+	Hs
		935016 CHD5_HUMAN (86-1909): 0: 1584: 71.18		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		1086233 CHD5_HUMAN (86-1909): 0: 1584: 71.18		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		828213 CHD3_HUMAN (23-1905): 0: 1595: 66.89		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Dm
		332725 CHDM_DROME (1-1904): 0: 1364: 50.85		H3_DROME (1-136): 3.73e-61: 186: 100.00
+	Ce
		104625 LE418_CAEEL (85-1903): 0: 1182: 39.96		HCP3_CAEEL (11-131): 1e-44: 149: 48.39
+	Sp
		144536 HRP3_SCHPO (535-1673): 0: 816: 28.33		H31_SCHPO (1-136): 2.22e-59: 181: 91.91
+	Hs
		935324 CHD7_HUMAN (3-1678): 0: 805: 23.02		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		952670 CHD7_HUMAN (3-1678): 0: 805: 23.02		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Mm
		935460 SMCA5_MOUSE (601-1624): 0: 795: 26.39		H31_MOUSE (1-136): 1.98e-62: 189: 99.27
+	Mm
		952266 SMCA5_MOUSE (601-1624): 0: 795: 26.39		H32_MOUSE (1-136): 3.73e-61: 186: 100.00
+	Mm
		952763 SMCA5_MOUSE (601-1624): 0: 795: 26.39		H33_MOUSE (1-136): 1.59e-61: 186: 97.06
+	Hs
		828410 CHD7_HUMAN (3-1678): 0: 805: 23.02		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Hs
		229341 SMCA5_HUMAN (578-1624): 0: 791: 26.01		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00