HitPredict

Interactor 1: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Interactor 2: H2A2B (Q8IUE6)
Histone H2A type 2-B (H2A-clustered histone 21)
Gene: H2AC21

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32744500
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1912 Hs			1 130
+	Hs
		1059795 CHD4_HUMAN (1-1912): 0: 1719: 100.00		H2A1H_HUMAN (1-128): 7.7e-68: 202: 95.31
+	Hs
		391704 CHD4_HUMAN (1-1912): 0: 1719: 100.00		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		470387 CHD4_HUMAN (1-1912): 0: 1719: 100.00		H2A1_HUMAN (1-130): 8.04e-68: 202: 94.62
+	Hs
		1059647 CHD4_HUMAN (1-1912): 0: 1719: 100.00		H2A2C_HUMAN (1-127): 3.2e-67: 200: 96.06
+	Hs
		555466 CHD4_HUMAN (1-1912): 0: 1719: 100.00		H2AX_HUMAN (1-123): 4.57e-66: 198: 95.94
+	Hs
		1018640 CHD3_HUMAN (23-1905): 0: 1595: 66.89		H2A1H_HUMAN (1-128): 7.7e-68: 202: 95.31
+	Hs
		391675 CHD3_HUMAN (23-1905): 0: 1595: 66.89		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Dm
		332757 CHDM_DROME (1-1904): 0: 1364: 50.85		H2A_DROME (17-122): 2.2e-58: 178: 93.40
+	Sp
		144533 HRP3_SCHPO (535-1673): 0: 816: 28.33		H2A2_SCHPO (1-129): 4.54e-62: 187: 80.15
+	Hs
		229433 SMCA5_HUMAN (578-1624): 0: 791: 26.01		H2A2B_HUMAN (1-130): 2.22e-71: 211: 100.00
+	Hs
		229279 SMCA5_HUMAN (578-1624): 0: 791: 26.01		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		229296 SMCA5_HUMAN (578-1624): 0: 791: 26.01		H2AX_HUMAN (1-123): 4.57e-66: 198: 95.94
+	Hs
		391728 CHD9_HUMAN (111-1653): 0: 783: 22.99		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Sp
		144532 HRP3_SCHPO (535-1673): 0: 816: 28.33		H2A1_SCHPO (1-121): 7.16e-54: 167: 83.74
+	Hs
		470278 SMCA1_HUMAN (617-1597): 0: 779: 27.44		H2A1_HUMAN (1-130): 8.04e-68: 202: 94.62
+	Hs
		555306 SMCA1_HUMAN (617-1597): 0: 779: 27.44		H2AX_HUMAN (1-123): 4.57e-66: 198: 95.94
+	Hs
		391915 CHD8_HUMAN (489-1678): 0: 752: 28.31		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		555654 CHD8_HUMAN (489-1678): 0: 752: 28.31		H2AX_HUMAN (1-123): 4.57e-66: 198: 95.94
+	Hs
		151474 CHD2_HUMAN (493-1689): 0: 739: 30.57		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Sc
		392360 CHD1_YEAST (515-1383): 0: 777: 35.17		H2A2_YEAST (16-121): 8.79e-53: 164: 83.96