Protein: CREB5
Cyclic AMP-responsive element-binding protein 5 (CREB-5) (cAMP-responsive element-binding protein 5) (cAMP-response element-binding protein A) (CRE-BPa)

Gene: CREB5
Organism: Homo sapiens
Interactions: 170
UniProt ID: Q02930

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

401872

JUN
Transcription factor Jun

8

19

Small-scale

0.973

High

548298

FOSL2
Fos-related antigen 2

7

20

High-throughput

0.972

High

345402

FOS
Protein c-Fos

6

20

High-throughput

0.947

High

548238

FOSL1
Fos-related antigen 1

4

19

High-throughput

0.909

High

973646

BATF3
Basic leucine zipper transcriptional factor ATF-like 3

4

20

High-throughput

0.902

High

157199

BACH1
Transcription regulator protein BACH1

3

20

High-throughput

0.861

High

547788

ATF2
Cyclic AMP-dependent transcription factor ATF-2

3

18

High-throughput

0.861

High

568088

JUND
Transcription factor JunD

3

17

High-throughput

0.861

High

568260

ATF7
Cyclic AMP-dependent transcription factor ATF-7

3

17

High-throughput

0.861

High

862613

FOSB
Protein FosB

3

20

High-throughput

0.858

High

973553

CREB5
Cyclic AMP-responsive element-binding protein 5

3

17

Small-scale

0.849

High

566750

JUNB
Transcription factor JunB

2

19

High-throughput

0.811

High

973609

JDP2
Jun dimerization protein 2

2

19

High-throughput

0.783

High

876591

AF17
Protein AF-17

4

6

High-throughput

0.698

High

862902

CEBPG
CCAAT/enhancer-binding protein gamma

1

17

High-throughput

0.691

High

973637

BACH2
Transcription regulator protein BACH2

1

20

High-throughput

0.691

High

973618

MDFI
MyoD family inhibitor

4

0

High-throughput

0.677

High

283185

RGS20
Regulator of G-protein signaling 20

3

2

High-throughput

0.675

High

327976

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

3

6

High-throughput

0.675

High

973620

KIFC3
Kinesin-like protein KIFC3

3

3

High-throughput

0.675

High

973612

RBPMS
RNA-binding protein with multiple splicing

3

0

High-throughput

0.646

High

973633

KRA32
Keratin-associated protein 3-2

4

1

High-throughput

0.637

High

973657

ARI1
E3 ubiquitin-protein ligase ARIH1

2

7

High-throughput

0.628

High

569622

CEBPB
CCAAT/enhancer-binding protein beta

1

20

High-throughput

0.618

High

208349

SPY1
Protein sprouty homolog 1

3

4

High-throughput

0.616

High

889452

KR108
Keratin-associated protein 10-8

3

20

High-throughput

0.616

High

889746

KR109
Keratin-associated protein 10-9

3

20

High-throughput

0.616

High

973583

K1C40
Keratin, type I cytoskeletal 40

3

5

High-throughput

0.616

High

973594

ATL4
ADAMTS-like protein 4

3

1

High-throughput

0.616

High

973619

KR412
Keratin-associated protein 4-12

3

20

High-throughput

0.616

High

973627

KRA92
Keratin-associated protein 9-2

3

20

High-throughput

0.616

High

973632

KRA42
Keratin-associated protein 4-2

3

20

High-throughput

0.616

High

238107

LMX1B
LIM homeobox transcription factor 1-beta

2

5

High-throughput

0.606

High

280104

SNPC5
snRNA-activating protein complex subunit 5

2

1

High-throughput

0.606

High

588294

FST
Follistatin

2

1

High-throughput

0.606

High

612842

FBLN1
Fibulin-1

2

6

High-throughput

0.606

High

829827

HXA1
Homeobox protein Hox-A1

2

7

High-throughput

0.606

High

973556

TP53B
TP53-binding protein 1

2

3

High-throughput

0.606

High

973559

FHL3
Four and a half LIM domains protein 3

2

3

High-throughput

0.606

High

973560

K1H1
Keratin, type I cuticular Ha1

2

5

High-throughput

0.606

High

973577

INT11
Integrator complex subunit 11

2

2

High-throughput

0.606

High

973586

SPOPL
Speckle-type POZ protein-like

2

3

High-throughput

0.606

High

973614

AJUBA
LIM domain-containing protein ajuba

2

3

High-throughput

0.606

High

973623

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

2

8

High-throughput

0.606

High

973640

PRD14
PR domain zinc finger protein 14

2

1

High-throughput

0.606

High

973641

RN208
RING finger protein 208

2

1

High-throughput

0.606

High

973647

APC11
Anaphase-promoting complex subunit 11

2

3

High-throughput

0.606

High

973653

RGS17
Regulator of G-protein signaling 17

2

2

High-throughput

0.606

High

973655

AKP8L
A-kinase anchor protein 8-like

2

1

High-throughput

0.606

High

642042

KRA59
Keratin-associated protein 5-9

3

20

High-throughput

0.604

High

973600

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

3

5

High-throughput

0.603

High

973584

Q6FG41
Protein c-Fos

1

20

High-throughput

0.594

High

889228

KR107
Keratin-associated protein 10-7

2

20

High-throughput

0.586

High

973557

TRAF2
TNF receptor-associated factor 2

2

3

High-throughput

0.583

High

67044

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.580

High

175431

SIVA
Apoptosis regulatory protein Siva

2

0

High-throughput

0.580

High

536790

TRI27
Zinc finger protein RFP

2

0

High-throughput

0.580

High

971118

ID3
DNA-binding protein inhibitor ID-3

2

0

High-throughput

0.580

High

973574

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.580

High

973613

TSR2
Pre-rRNA-processing protein TSR2 homolog

2

0

High-throughput

0.580

High

973615

ZN363
RING finger and CHY zinc finger domain-containing protein 1

2

0

High-throughput

0.580

High

973617

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

2

0

High-throughput

0.580

High

973645

UNKL
Putative E3 ubiquitin-protein ligase UNKL

2

0

High-throughput

0.580

High

973648

WWOX
WW domain-containing oxidoreductase

2

0

High-throughput

0.580

High

973656

ZN330
Zinc finger protein 330

2

0

High-throughput

0.580

High

973597

NT2NA
Notch homolog 2 N-terminal-like protein A

2

2

High-throughput

0.578

High

973582

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

2

6

High-throughput

0.574

High

208127

SPY2
Protein sprouty homolog 2

1

4

High-throughput

0.573

High

580015

K1C15
Keratin, type I cytoskeletal 15

1

4

High-throughput

0.573

High

734601

TRI23
E3 ubiquitin-protein ligase TRIM23

1

4

High-throughput

0.573

High

973562

TRIP6
Thyroid receptor-interacting protein 6

1

3

High-throughput

0.573

High

973572

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

3

High-throughput

0.573

High

973605

TRI42
Tripartite motif-containing protein 42

2

7

High-throughput

0.561

High

889043

KR105
Keratin-associated protein 10-5

2

20

High-throughput

0.558

High

889926

KR10B
Keratin-associated protein 10-11

2

20

High-throughput

0.558

High

49178

CIB4
Calcium and integrin-binding family member 4

2

1

High-throughput

0.553

High

208417

SPY3
Protein sprouty homolog 3

2

4

High-throughput

0.553

High

213938

KRT86
Keratin, type II cuticular Hb6

2

4

High-throughput

0.553

High

398515

PPB1
Alkaline phosphatase, placental type

2

1

High-throughput

0.553

High

887731

KR10A
Keratin-associated protein 10-10

2

20

High-throughput

0.553

High

943626

KRT83
Keratin, type II cuticular Hb3

2

4

High-throughput

0.553

High

943666

KRT85
Keratin, type II cuticular Hb5

2

4

High-throughput

0.553

High

973573

GT253
Inactive glycosyltransferase 25 family member 3

2

1

High-throughput

0.553

High

973587

KR511
Keratin-associated protein 5-11

2

20

High-throughput

0.553

High

973588

KRA57
Keratin-associated protein 5-7

2

20

High-throughput

0.553

High

973590

KRA54
Keratin-associated protein 5-4

2

18

High-throughput

0.553

High

973604

KRA13
Keratin-associated protein 1-3

2

20

High-throughput

0.553

High

973624

KRA98
Keratin-associated protein 9-8

2

20

High-throughput

0.553

High

973626

KRA93
Keratin-associated protein 9-3

2

20

High-throughput

0.553

High

973629

KRA41
Keratin-associated protein 4-1

2

20

High-throughput

0.553

High

973630

KRA45
Keratin-associated protein 4-5

2

20

High-throughput

0.553

High

973631

KRA44
Keratin-associated protein 4-4

2

20

High-throughput

0.553

High

973634

KRA31
Keratin-associated protein 3-1

2

1

High-throughput

0.553

High

973636

KRA15
Keratin-associated protein 1-5

2

20

High-throughput

0.553

High

973639

SPY4
Protein sprouty homolog 4

2

4

High-throughput

0.553

High

973652

RIM3A
RIMS-binding protein 3A

1

0

High-throughput

0.549

High

216496

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

5

High-throughput

0.536

High

973558

CTBP1
C-terminal-binding protein 1

1

4

High-throughput

0.536

High

973561

ZMY11
Zinc finger MYND domain-containing protein 11

1

6

High-throughput

0.536

High

973596

CENPQ
Centromere protein Q

1

5

High-throughput

0.536

High

973644

EGLN3
Prolyl hydroxylase EGLN3

1

5

High-throughput

0.536

High

973649

ANFY1
Rabankyrin-5

1

2

High-throughput

0.536

High

973650

FBLN5
Fibulin-5

1

6

High-throughput

0.536

High

888683

KR101
Keratin-associated protein 10-1

2

20

High-throughput

0.533

High

973625

KRA94
Keratin-associated protein 9-4

1

20

High-throughput

0.523

High

973638

TSG10
Testis-specific gene 10 protein

1

4

High-throughput

0.523

High

660466

GRN
Progranulin

1

0

High-throughput

0.493

High

868149

ATX3
Ataxin-3

1

0

High-throughput

0.493

High

973563

INSY1
Inhibitory synaptic factor 1

1

3

High-throughput

0.489

High

214221

SPOP
Speckle-type POZ protein

1

3

Small-scale

0.481

High

129743

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

1

High-throughput

0.479

High

749397

BRCA1
Breast cancer type 1 susceptibility protein

1

7

High-throughput

0.479

High

940802

RNF4
E3 ubiquitin-protein ligase RNF4

1

5

High-throughput

0.479

High

967119

EWS
RNA-binding protein EWS

1

3

High-throughput

0.479

High

973606

SLX4
Structure-specific endonuclease subunit SLX4

1

10

High-throughput

0.479

High

973610

ESR2
Estrogen receptor beta

1

17

High-throughput

0.479

High

973616

CIC
Protein capicua homolog

1

15

High-throughput

0.479

High

103725

G5E9A7
DM1 locus, WD repeat containing

1

12

High-throughput

0.470

High

176017

GPR37
Prosaposin receptor GPR37

1

2

High-throughput

0.470

High

484594

NT2NC
Notch homolog 2 N-terminal-like protein C

1

3

High-throughput

0.470

High

973555

Q08AG9
Steroid 21-hydroxylase

1

3

High-throughput

0.470

High

973635

KRA24
Keratin-associated protein 2-4

1

20

High-throughput

0.470

High

444012

CP21A
Steroid 21-hydroxylase

1

3

High-throughput

0.439

High

473276

KRA23
Keratin-associated protein 2-3

1

20

High-throughput

0.439

High

888848

KR103
Keratin-associated protein 10-3

1

20

High-throughput

0.439

High

973554

KRA11
Keratin-associated protein 1-1

1

20

High-throughput

0.439

High

973591

KRA53
Keratin-associated protein 5-3

1

20

High-throughput

0.439

High

973598

R144B
E3 ubiquitin-protein ligase RNF144B

1

6

High-throughput

0.439

High

973628

KR411
Keratin-associated protein 4-11

1

20

High-throughput

0.439

High

650082

CO8A1
Collagen alpha-1(VIII) chain

3

0

High-throughput

0.352

High

973589

KRA56
Keratin-associated protein 5-6

3

0

High-throughput

0.352

High

973654

PP13
Galactoside-binding soluble lectin 13

3

0

High-throughput

0.345

High

156140

TSN4
Tetraspanin-4

2

0

High-throughput

0.316

High

180698

PA2GX
Group 10 secretory phospholipase A2

2

0

High-throughput

0.316

High

207309

FRS3
Fibroblast growth factor receptor substrate 3

2

0

High-throughput

0.316

High

499322

RET3
Retinol-binding protein 3

2

0

High-throughput

0.316

High

623572

IBP6
Insulin-like growth factor-binding protein 6

2

0

High-throughput

0.316

High

888528

KR123
Keratin-associated protein 12-3

2

0

High-throughput

0.316

High

973564

KR192
Keratin-associated protein 19-2

2

0

High-throughput

0.316

High

973565

KRA61
Keratin-associated protein 6-1

2

0

High-throughput

0.316

High

973566

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

973568

KR196
Keratin-associated protein 19-6

2

0

High-throughput

0.316

High

973569

KR195
Keratin-associated protein 19-5

2

0

High-throughput

0.316

High

973575

LCE1C
Late cornified envelope protein 1C

2

0

High-throughput

0.316

High

973578

LCE4A
Late cornified envelope protein 4A

2

0

High-throughput

0.316

High

973579

LCE2A
Late cornified envelope protein 2A

2

0

High-throughput

0.316

High

973580

LCE2C
Late cornified envelope protein 2C

2

0

High-throughput

0.316

High

973581

LCE5A
Late cornified envelope protein 5A

2

0

High-throughput

0.316

High

973585

NADE
Glutamine-dependent NAD(+) synthetase

2

0

High-throughput

0.316

High

973592

UFSP1
Inactive Ufm1-specific protease 1

2

0

High-throughput

0.316

High

973593

CDPF1
Cysteine-rich DPF motif domain-containing protein 1

2

0

High-throughput

0.316

High

973595

KRA52
Keratin-associated protein 5-2

2

0

High-throughput

0.316

High

973599

KR193
Keratin-associated protein 19-3

2

0

High-throughput

0.316

High

973601

SPT12
Spermatogenesis-associated protein 12

2

0

High-throughput

0.316

High

973602

KRA81
Keratin-associated protein 8-1

2

0

High-throughput

0.316

High

973603

KRA71
Keratin-associated protein 7-1

2

0

High-throughput

0.316

High

973611

PCSK5
Proprotein convertase subtilisin/kexin type 5

2

0

High-throughput

0.316

High

973622

CNFN
Cornifelin

2

0

High-throughput

0.316

High

973642

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

2

0

High-throughput

0.316

High

973643

MMAD
Cobalamin trafficking protein CblD

2

0

High-throughput

0.316

High

973651

ZMAT5
Zinc finger matrin-type protein 5

2

0

High-throughput

0.316

High

973571

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

2

0

High-throughput

0.304

High

973567

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.268

Low

506

NBPFJ
Neuroblastoma breakpoint family member 19

1

0

High-throughput

0.251

Low

973570

KR221
Keratin-associated protein 22-1

1

0

High-throughput

0.251

Low

973576

LCE1F
Late cornified envelope protein 1F

1

0

High-throughput

0.251

Low

973607

PRR22
Proline-rich protein 22

1

0

High-throughput

0.251

Low

973608

SRB4D
Scavenger receptor cysteine-rich domain-containing group B protein

1

0

High-throughput

0.251

Low

973621

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024