HitPredict

Interactor 1: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Interactor 2: P66B (Q8WXI9)
Transcriptional repressor p66-beta (GATA zinc finger domain-containing protein 2B) (p66/p68)
Gene: GATAD2B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.749

The method score is based on:

Property Details
Experiments 26186194, 28514442, 24981860, 33961781, 28977666, 32744500, 33283408, 21555454
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000781 - chromosome, telomeric region
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 8 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1912
Hs

1 593
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+ Dm
+ Dm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024