Interactor 1: G5EDD8 (G5EDD8)
Skp1-related protein
Gene: skr-2

Interactor 2: CUL1 (Q17389)
Cullin-1 (CUL-1) (Abnormal cell lineage protein 19)
Gene: cul-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.890

The method score is based on:

Property Details
Experiments 28739890, 11864567, 11864566, 38354250
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~Skp1_POZ
Common GO terms GO:0005737 - cytoplasm
GO:0008285 - negative regulation of cell population proliferation
GO:0009792 - embryo development ending in birth or egg hatching
GO:0010826 - negative regulation of centrosome duplication
GO:0016567 - protein ubiquitination
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 174
Ce

1 780
+ Ce
+ Mm
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs
+ At
+ At
+ At
+ At
+ At
+ At
+ Sp
+ Ce
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024