Protein: LPXN
Leupaxin

Gene: LPXN
Organism: Homo sapiens
Interactions: 83
UniProt ID: O60711

Gene Ontology (top 5):
GO:0002102 - podosome
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

253999

GIT1
ARF GTPase-activating protein GIT1

4

14

Small-scale

0.896

High

253936

RBTN1
Rhombotin-1

3

20

High-throughput

0.875

High

253950

ARHG7
Rho guanine nucleotide exchange factor 7

3

11

High-throughput

0.855

High

253951

GIT2
ARF GTPase-activating protein GIT2

3

20

High-throughput

0.855

High

253953

ARHG6
Rho guanine nucleotide exchange factor 6

3

12

High-throughput

0.855

High

253963

CYTSA
Cytospin-A

3

20

High-throughput

0.855

High

253966

MIB1
E3 ubiquitin-protein ligase MIB1

3

13

High-throughput

0.855

High

253990

PARVA
Alpha-parvin

3

10

High-throughput

0.855

High

253956

TRIP6
Thyroid receptor-interacting protein 6

2

19

High-throughput

0.811

High

253972

LPP
Lipoma-preferred partner

2

18

High-throughput

0.811

High

253986

PDLI7
PDZ and LIM domain protein 7

2

18

High-throughput

0.811

High

253994

LIMD1
LIM domain-containing protein 1

2

19

High-throughput

0.811

High

253971

LMO3
LIM domain only protein 3

2

20

High-throughput

0.783

High

253967

PKHH2
Pleckstrin homology domain-containing family H member 2

4

16

High-throughput

0.703

High

253946

MTG8
Protein CBFA2T1

4

2

High-throughput

0.703

High

253941

LIMS1
LIM and senescent cell antigen-like-containing domain protein 1

1

19

High-throughput

0.698

High

253939

HXC9
Homeobox protein Hox-C9

4

5

High-throughput

0.698

High

253944

FAK1
Focal adhesion kinase 1

4

20

High-throughput

0.697

High

253957

ZYX
Zyxin

1

18

High-throughput

0.691

High

253961

PKHN1
Pleckstrin homology domain-containing family N member 1

3

10

High-throughput

0.675

High

253928

PCNT
Pericentrin

3

16

High-throughput

0.662

High

253937

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

3

6

High-throughput

0.662

High

253943

PTN12
Tyrosine-protein phosphatase non-receptor type 12

3

16

High-throughput

0.662

High

253947

PAK1
Serine/threonine-protein kinase PAK 1

3

8

High-throughput

0.662

High

253958

CCDC6
Coiled-coil domain-containing protein 6

3

16

High-throughput

0.662

High

253981

ATX2
Ataxin-2

3

11

High-throughput

0.662

High

253983

PPIP2
Proline-serine-threonine phosphatase-interacting protein 2

3

1

High-throughput

0.662

High

254000

ZN281
Zinc finger protein 281

3

18

High-throughput

0.662

High

253934

VINC
Vinculin

3

18

High-throughput

0.661

High

253954

PCM1
Pericentriolar material 1 protein

3

0

High-throughput

0.634

High

253976

EDC3
Enhancer of mRNA-decapping protein 3

3

0

High-throughput

0.634

High

253948

PAK2
Serine/threonine-protein kinase PAK 2

2

8

High-throughput

0.628

High

253960

QRIC1
Transcriptional regulator QRICH1

2

17

High-throughput

0.628

High

253964

CEP68
Centrosomal protein of 68 kDa

2

8

High-throughput

0.628

High

253968

DCP1B
mRNA-decapping enzyme 1B

2

7

High-throughput

0.628

High

253979

CK5P2
CDK5 regulatory subunit-associated protein 2

2

16

High-throughput

0.628

High

253991

MIOS
GATOR2 complex protein MIOS

2

1

High-throughput

0.628

High

253978

P121A
Nuclear envelope pore membrane protein POM 121

3

15

High-throughput

0.609

High

253930

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

2

2

High-throughput

0.606

High

253935

AGT1
Alanine--glyoxylate aminotransferase

2

1

High-throughput

0.606

High

253962

TENS2
Tensin-2

2

8

High-throughput

0.606

High

253996

PKHH1
Pleckstrin homology domain-containing family H member 1

3

11

High-throughput

0.604

High

253938

AQP1
Aquaporin-1

2

0

High-throughput

0.580

High

253952

FAK2
Protein-tyrosine kinase 2-beta

2

20

Small-scale

0.576

High

253949

ILK
Scaffold protein ILK

1

20

High-throughput

0.575

High

253984

PARVG
Gamma-parvin

1

20

High-throughput

0.575

High

253992

LMCD1
LIM and cysteine-rich domains protein 1

1

17

High-throughput

0.575

High

253965

NUP54
Nucleoporin p54

2

3

High-throughput

0.574

High

253969

TXLNB
Beta-taxilin

1

14

High-throughput

0.573

High

254002

NEMO
NF-kappa-B essential modulator

1

9

High-throughput

0.561

High

161909

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

9

High-throughput

0.541

High

253942

HXA1
Homeobox protein Hox-A1

1

12

High-throughput

0.541

High

253980

NECD
Necdin

1

8

High-throughput

0.541

High

253982

ZN426
Zinc finger protein 426

1

17

High-throughput

0.541

High

253988

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

1

High-throughput

0.541

High

254001

ZN175
Zinc finger protein 175

1

7

High-throughput

0.541

High

245822

KIF1B
Kinesin-like protein KIF1B

1

6

High-throughput

0.536

High

253945

BTK
Tyrosine-protein kinase BTK

1

20

High-throughput

0.536

High

253975

OPTN
Optineurin

1

13

High-throughput

0.515

High

253959

MK06
Mitogen-activated protein kinase 6

1

9

High-throughput

0.508

High

253987

PLS4
Phospholipid scramblase 4

1

1

High-throughput

0.508

High

253993

HDAC6
Protein deacetylase HDAC6

1

7

High-throughput

0.508

High

253974

PF21A
PHD finger protein 21A

1

15

High-throughput

0.494

High

253931

GCR
Glucocorticoid receptor

1

17

Small-scale

0.481

High

253932

ITA4
Integrin alpha-4

1

10

Small-scale

0.479

High

253933

EGR1
Early growth response protein 1

1

20

High-throughput

0.479

High

69719

SFI1
Protein SFI1 homolog

1

0

High-throughput

0.460

High

253977

RUSF1
RUS family member 1

1

0

High-throughput

0.458

High

239507

MED14
Mediator of RNA polymerase II transcription subunit 14

1

6

High-throughput

0.445

High

253926

BCAR3
Breast cancer anti-estrogen resistance protein 3

1

20

High-throughput

0.445

High

253927

PAK3
Serine/threonine-protein kinase PAK 3

1

8

High-throughput

0.445

High

253940

ETV6
Transcription factor ETV6

1

4

High-throughput

0.445

High

253955

MED1
Mediator of RNA polymerase II transcription subunit 1

1

7

High-throughput

0.445

High

253973

MED12
Mediator of RNA polymerase II transcription subunit 12

1

10

High-throughput

0.445

High

253985

TENS1
Tensin-1

1

12

High-throughput

0.445

High

253997

CP131
Centrosomal protein of 131 kDa

1

8

High-throughput

0.445

High

104922

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

253925

MED24
Mediator of RNA polymerase II transcription subunit 24

1

0

High-throughput

0.426

High

253989

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.426

High

253995

MED13
Mediator of RNA polymerase II transcription subunit 13

1

0

High-throughput

0.426

High

253998

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.426

High

253970

RN214
RING finger protein 214

1

0

High-throughput

0.251

Low

253929

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025