HitPredict

Interactor 1: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Interactor 2: THOC1 (Q96FV9)
THO complex subunit 1 (Nuclear matrix protein p84) (p84N5) (hTREX84)
Gene: THOC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29395067, 37020021
Identification Methods	proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0006397 - mRNA processing and 1 others more... GO:0016607 - nuclear speck
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 657
+	Hs
		1099013 SRSF9_HUMAN (1-239): 4.19e-66: 206: 60.25		THOC1_HUMAN (1-657): 0: 1010: 100.00
+	Hs
		1062077 SRSF4_HUMAN (17-243): 1.37e-49: 171: 37.66		THOC1_HUMAN (1-657): 0: 1010: 100.00
+	Hs
		1016563 SRSF3_HUMAN (15-99): 9.37e-28: 105: 43.53		THOC1_HUMAN (1-657): 0: 1010: 100.00
+	Hs
		1160038 SRSF7_HUMAN (14-105): 7.37e-23: 94.8: 40.22		THOC1_HUMAN (1-657): 0: 1010: 100.00