HitPredict

Interactor 1: PSMD6 (Q15008)
26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A)
Gene: PSMD6

Interactor 2: DDI1 (Q8WTU0)
Protein DDI1 homolog 1 (EC 3.4.23.-)
Gene: DDI1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RPN7~ubiquitin
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 389 Hs			1 396
+	Hs
		1062825 PSMD6_HUMAN (1-389): 5.58e-137: 397: 100.00		DDI2_HUMAN (1-392): 2.76e-155: 445: 70.93
+	Hs
		121821 PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03		DDI1_HUMAN (1-396): 4.1e-163: 465: 100.00
+	Hs
		121791 PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03		DDI2_HUMAN (1-392): 2.76e-155: 445: 70.93
+	Hs
		1062897 PSMD6_HUMAN (1-389): 5.58e-137: 397: 100.00		UBQL1_HUMAN (5-249): 3.83e-47: 171: 14.74
+	Hs
		1062891 PSMD6_HUMAN (1-389): 5.58e-137: 397: 100.00		UBQL2_HUMAN (5-249): 4.55e-46: 168: 14.74
+	Hs
		1062884 PSMD6_HUMAN (1-389): 5.58e-137: 397: 100.00		UBQL4_HUMAN (8-249): 3.58e-43: 160: 14.24
+	Dm
		1358537 PSMD6_DROME (1-389): 2.36e-125: 368: 70.18		Q9VWD9_DROME (5-249): 3.39e-41: 154: 13.55
+	Hs
		923997 PSMD6_HUMAN (1-389): 5.58e-137: 397: 100.00		RS27A_HUMAN (5-93): 5.56e-24: 98.8: 17.98
+	Hs
		121871 PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03		UBQL1_HUMAN (5-249): 3.83e-47: 171: 14.74
+	Hs
		121867 PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03		UBQL2_HUMAN (5-249): 4.55e-46: 168: 14.74
+	Hs
		888457 EIF3E_HUMAN (26-387): 7.71e-74: 238: 14.04		UBQL2_HUMAN (5-249): 4.55e-46: 168: 14.74
+	Hs
		121863 PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03		UBQL4_HUMAN (8-249): 3.58e-43: 160: 14.24
+	Dm
		1180727 PSD11_DROME (7-387): 4.3e-77: 246: 13.32		Q9VWD9_DROME (5-249): 3.39e-41: 154: 13.55
+	Hs
		121730 PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03		RS27A_HUMAN (5-93): 5.56e-24: 98.8: 17.98