Protein: Q9VQL7
Fatty acid synthase (EC 1.1.1.100) (EC 1.3.1.39) (EC 2.3.1.38) (EC 2.3.1.39) (EC 2.3.1.41) (EC 2.3.1.85) (EC 3.1.2.14) (EC 4.2.1.59)

Gene: Q9VQL7, FASN1
Organism: Drosophila melanogaster
Interactions: 121
UniProt ID: Q9VQL7

Gene Ontology (top 5):
GO:0004312 - fatty acid synthase activity
GO:0004313 - [acyl-carrier-protein] S-acetyltransferase activity
GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0004316 - 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0006633 - fatty acid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1484307

Q9VQL1
serine--tRNA ligase

2

1

High-throughput

0.659

High

1484351

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

2

0

High-throughput

0.617

High

1484370

Q9W3N1
RH59310p

2

0

High-throughput

0.617

High

1011997

CCD1P
Probable cytochrome P450 12d1 proximal, mitochondrial

1

2

High-throughput

0.553

High

652111

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

2

3

High-throughput

0.521

High

782803

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

2

1

High-throughput

0.521

High

1176357

VATA2
V-type proton ATPase catalytic subunit A isoform 2

2

1

High-throughput

0.521

High

1265856

Q7K3J0
T-complex protein 1 subunit theta

2

1

High-throughput

0.521

High

1268194

Q7KN94
Electron transfer flavoprotein subunit alpha

2

1

High-throughput

0.521

High

1465634

Q9V470
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

2

2

High-throughput

0.521

High

1468671

Q9VAY2
Heat shock protein 83

2

9

High-throughput

0.521

High

1474987

IPO9
Importin-9

2

1

High-throughput

0.521

High

1484358

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

2

1

High-throughput

0.521

High

1484362

Q9VWL0
Mec2

2

1

High-throughput

0.521

High

1268734

CCD1D
Probable cytochrome P450 12d1 distal, mitochondrial

1

2

High-throughput

0.514

High

1469679

Q9VBU5
3-dehydrosphinganine reductase

1

3

High-throughput

0.514

High

1477887

Q9VIX4
Acyl-coenzyme A oxidase

1

1

High-throughput

0.514

High

1479426

NFS1
Cysteine desulfurase, mitochondrial

1

3

High-throughput

0.514

High

1484363

DHB4
Peroxisomal multifunctional enzyme type 2

1

2

High-throughput

0.514

High

1268114

Q7KN85
ATP-citrate synthase

1

2

High-throughput

0.445

High

197178

RAB2
Ras-related protein Rab-2

1

1

High-throughput

0.437

High

1069207

Q0E8E8
Phosphate carrier protein, mitochondrial

1

2

High-throughput

0.437

High

1172682

SIMA
Protein similar

1

1

High-throughput

0.437

High

1176110

DX39B
ATP-dependent RNA helicase WM6

1

3

High-throughput

0.437

High

1260774

Q76NQ0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.437

High

1268230

Q7KN97
Pyruvate carboxylase

1

3

High-throughput

0.437

High

1269262

Q7KTD0
ABC-type glutathione-S-conjugate transporter

1

2

High-throughput

0.437

High

1303740

AKT1
RAC serine/threonine-protein kinase

1

1

High-throughput

0.437

High

1482590

RHEB
GTP-binding protein Rheb homolog

1

3

High-throughput

0.437

High

1484368

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

4

High-throughput

0.437

High

86584

B9EQV3
Endoplasmic reticulum transmembrane protein

1

1

High-throughput

0.407

High

234796

O46067
Hypoxia up-regulated protein 1

1

3

High-throughput

0.407

High

304156

RAB7
Ras-related protein Rab7

1

3

High-throughput

0.407

High

565048

ATNA
Sodium/potassium-transporting ATPase subunit alpha

1

3

High-throughput

0.407

High

614332

SGG
Protein kinase shaggy

1

4

High-throughput

0.407

High

875029

PRS4
26S proteasome regulatory subunit 4

1

3

High-throughput

0.407

High

875298

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.407

High

1070122

Q0E9E2
Pyruvate carboxylase

1

2

High-throughput

0.407

High

1173592

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

1

High-throughput

0.407

High

1176822

NCPR
NADPH--cytochrome P450 reductase

1

1

High-throughput

0.407

High

1236904

Q6NP35
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.407

High

1264158

Q7K0E6
Aspartate--tRNA ligase, cytoplasmic

1

3

High-throughput

0.407

High

1267741

Q7KMQ0
26S proteasome regulatory subunit 7

1

2

High-throughput

0.407

High

1267980

TERA
Transitional endoplasmic reticulum ATPase TER94

1

3

High-throughput

0.407

High

1268046

Q7KN75
Dodeca-satellite-binding protein 1, isoform A

1

4

High-throughput

0.407

High

1306173

Q8IRD3
Glutathione peroxidase

1

1

High-throughput

0.407

High

1321463

Q8MSW0
Isoleucine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.407

High

1343360

OLA1
Obg-like ATPase 1

1

1

High-throughput

0.407

High

1344466

Q8SYG3
E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.407

High

1345303

Q8T0L3
E1 ubiquitin-activating enzyme

1

1

High-throughput

0.407

High

1375332

VDAC
Voltage-dependent anion-selective channel

1

2

High-throughput

0.407

High

1378498

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

2

High-throughput

0.407

High

1457454

XPO1
Exportin-1

1

4

High-throughput

0.407

High

1463891

SEC13
Protein SEC13 homolog

1

5

High-throughput

0.407

High

1464464

Q9V3V6
26S proteasome regulatory complex subunit p50

1

7

High-throughput

0.407

High

1465201

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.407

High

1465472

Q9V455
Importin subunit alpha

1

1

High-throughput

0.407

High

1466768

Q9V9Q4
LD43819p

1

2

High-throughput

0.407

High

1467969

Q9VAH7
N-terminal kinase-like protein

1

2

High-throughput

0.407

High

1472946

FLNA
Filamin-A

1

1

High-throughput

0.407

High

1476487

Q9VHN7
transketolase

1

1

High-throughput

0.407

High

1476805

ARL8
ADP-ribosylation factor-like protein 8

1

1

High-throughput

0.407

High

1477153

Q9VI53
LD44267p

1

2

High-throughput

0.407

High

1479156

Q9VK56
ABC-type glutathione-S-conjugate transporter

1

2

High-throughput

0.407

High

1480085

Q9VKZ8
Ubiquitin carboxyl-terminal hydrolase

1

6

High-throughput

0.407

High

1481071

Q9VLS7
LD21067p

1

1

High-throughput

0.407

High

1482341

Q9VN44
FI07923p

1

2

High-throughput

0.407

High

1484347

Q9VRD6
NTF2-related export protein

1

1

High-throughput

0.407

High

1484349

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

3

High-throughput

0.407

High

1484352

Q9VSI6
Isocitrate dehydrogenase [NADP]

1

1

High-throughput

0.407

High

1484357

Q9VVL7
Dihydrolipoyl dehydrogenase

1

3

High-throughput

0.407

High

1484359

Q9VW70
FI21813p1

1

2

High-throughput

0.407

High

1484360

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

2

High-throughput

0.407

High

1484361

Q9VWI2
N(Alpha)-acetyltransferase 15/16, isoform A

1

1

High-throughput

0.407

High

1484366

Q9W0E4
Aminopeptidase

1

1

High-throughput

0.407

High

1484367

SND1
Staphylococcal nuclease domain-containing protein 1

1

2

High-throughput

0.407

High

1484372

Q9W414
Regulatory particle triple-A ATPase 4

1

2

High-throughput

0.407

High

1484373

Q9W457
Serine hydroxymethyltransferase

1

1

High-throughput

0.407

High

715164

CLH
Clathrin heavy chain

2

0

High-throughput

0.298

High

1264557

Q7K110
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

0

High-throughput

0.298

High

1468491

Q9VAW3
glutamine--fructose-6-phosphate transaminase

2

0

High-throughput

0.298

High

1476298

Q9VHL2
T-complex protein 1 subunit eta

2

0

High-throughput

0.298

High

1484364

Q9VXQ5
Chaperonin containing TCP1 subunit 6

2

0

High-throughput

0.298

High

852237

COPB
Coatomer subunit beta

1

0

High-throughput

0.249

Low

1484369

Q9W1K4
Egalitarian, isoform B

1

0

High-throughput

0.249

Low

2738

A0A0B4LFU9
Anastral spindle 2, isoform B

1

0

High-throughput

0.232

Low

51928

PO210
Nuclear pore membrane glycoprotein 210

1

0

High-throughput

0.232

Low

53717

A1Z843
Nodal modulator 3

1

0

High-throughput

0.232

Low

57655

A1ZB71
Glutathione S transferase E6

1

0

High-throughput

0.232

Low

234632

VINC
Vinculin

1

0

High-throughput

0.232

Low

304270

ERD2
ER lumen protein-retaining receptor

1

0

High-throughput

0.232

Low

648960

ANXB9
Annexin B9

1

0

High-throughput

0.232

Low

835213

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

1

0

High-throughput

0.232

Low

1071054

Q0KIB3
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.232

Low

1267414

Q7KLX3
Translocon-associated protein subunit delta

1

0

High-throughput

0.232

Low

1305782

Q8IQZ7
FI19014p1

1

0

High-throughput

0.232

Low

1321736

Q8MT58
Carnosine dipeptidase 2, isoform A

1

0

High-throughput

0.232

Low

1346280

Q8T8W3
AT21416p

1

0

High-throughput

0.232

Low

1376867

LDH
L-lactate dehydrogenase

1

0

High-throughput

0.232

Low

1377701

FAXC
Failed axon connections

1

0

High-throughput

0.232

Low

1440617

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.232

Low

1464809

Q9V3Z4
GH11341p

1

0

High-throughput

0.232

Low

1465143

API5
Apoptosis inhibitor 5 homolog

1

0

High-throughput

0.232

Low

1465386

KRH2
Krueppel homolog 2

1

0

High-throughput

0.232

Low

1467003

Q9V9U3
LD45254p

1

0

High-throughput

0.232

Low

1468084

Q9VAL7
Calnexin 99A, isoform A

1

0

High-throughput

0.232

Low

1474181

ELP6
Elongator complex protein 6

1

0

High-throughput

0.232

Low

1474310

Q9VG31
Malic enzyme

1

0

High-throughput

0.232

Low

1478320

Q9VJD1
Glucosidase 2 subunit beta

1

0

High-throughput

0.232

Low

1480178

EF1D
Probable elongation factor 1-delta

1

0

High-throughput

0.232

Low

1481493

Q9VM57
Septin interacting protein 2, isoform A

1

0

High-throughput

0.232

Low

1483817

Q9VQ61
Aspartate aminotransferase

1

0

High-throughput

0.232

Low

1484203

Q9VQI5
Interferon-related developmental regulator 1

1

0

High-throughput

0.232

Low

1484348

Q9VRL1
GEO06356p1

1

0

High-throughput

0.232

Low

1484350

Q9VS47
Lysosomal dipeptide transporter MFSD1

1

0

High-throughput

0.232

Low

1484353

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.232

Low

1484354

ODR4
Protein odr-4 homolog

1

0

High-throughput

0.232

Low

1484355

FRL
Formin-like protein

1

0

High-throughput

0.232

Low

1484356

Q9VV75
AT02348p

1

0

High-throughput

0.232

Low

1484365

Q9VXV6
Secretory carrier-associated membrane protein

1

0

High-throughput

0.232

Low

1484371

Q9W3X6
fumarate hydratase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025