HitPredict

Interactor 1: PSMD6 (Q15008)
26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A)
Gene: PSMD6

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	35271311, 30442662, 27114451
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RPN7~ubiquitin
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 389 Hs			1 624
+	Hs
		1062897 PSMD6_HUMAN (1-389): 5.58e-137: 397: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		1062884 PSMD6_HUMAN (1-389): 5.58e-137: 397: 100.00		UBQL4_HUMAN (22-624): 2.17e-124: 382: 54.55
+	Dm
		1358537 PSMD6_DROME (1-389): 2.36e-125: 368: 70.18		Q9VWD9_DROME (26-617): 4.15e-130: 395: 44.35
+	Hs
		121867 PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		888457 EIF3E_HUMAN (26-387): 7.71e-74: 238: 14.04		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		121871 PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Dm
		1180727 PSD11_DROME (7-387): 4.3e-77: 246: 13.32		Q9VWD9_DROME (26-617): 4.15e-130: 395: 44.35
+	Hs
		121863 PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03		UBQL4_HUMAN (22-624): 2.17e-124: 382: 54.55
+	Hs
		1062848 PSMD6_HUMAN (1-389): 5.58e-137: 397: 100.00		DDI1_HUMAN (43-314): 2.92e-54: 191: 15.60
+	Hs
		1062825 PSMD6_HUMAN (1-389): 5.58e-137: 397: 100.00		DDI2_HUMAN (43-314): 6.26e-52: 185: 14.59
+	Hs
		923997 PSMD6_HUMAN (1-389): 5.58e-137: 397: 100.00		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		121821 PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03		DDI1_HUMAN (43-314): 2.92e-54: 191: 15.60
+	Hs
		121791 PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03		DDI2_HUMAN (43-314): 6.26e-52: 185: 14.59
+	Hs
		121731 PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		121730 PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27