HitPredict

Interactor 1: SART3 (Q15020)
Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (Tat-interacting protein of 110 kDa) (Tip110) (p110 nuclear RNA-binding protein)
Gene: SART3

Interactor 2: LSM7 (Q9UK45)
U6 snRNA-associated Sm-like protein LSm7
Gene: LSM7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	33961781, 15452143, 19615732
Identification Methods	affinity chromatography technology, fluorescent resonance energy transfer, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	LSM~Lsm_interact
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0017070 - U6 snRNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 963 Hs			1 103
+	Hs
		927951 SART3_HUMAN (1-963): 0: 638: 100.00		RSMN_HUMAN (8-96): 2.99e-25: 96.1: 28.57
+	Hs
		538962 SART3_HUMAN (1-963): 0: 638: 100.00		RSMB_HUMAN (8-96): 5.05e-25: 95.7: 28.57
+	Hs
		912043 SART3_HUMAN (1-963): 0: 638: 100.00		RUXG_HUMAN (8-90): 4.16e-24: 88.8: 32.53
+	Hs
		321401 SART3_HUMAN (1-963): 0: 638: 100.00		LSM8_HUMAN (15-94): 2.01e-22: 84.9: 32.50
+	Hs
		68420 SART3_HUMAN (1-963): 0: 638: 100.00		RUXGL_HUMAN (8-90): 2.38e-22: 84.2: 31.33
+	Hs
		912158 SART3_HUMAN (1-963): 0: 638: 100.00		LSM3_HUMAN (8-87): 1.19e-21: 83.4: 29.07
+	Ce
		1088923 SART3_CAEEL (73-962): 3.23e-124: 399: 24.26		Q23543_CAEEL (3-102): 1.55e-33: 113: 57.00
+	Ce
		954822 SART3_CAEEL (73-962): 3.23e-124: 399: 24.26		RSMB_CAEEL (14-96): 2.21e-22: 86.9: 25.88
+	Ce
		1088934 SART3_CAEEL (73-962): 3.23e-124: 399: 24.26		Q9U1W8_CAEEL (6-87): 1.61e-22: 85.3: 29.55
+	Ce
		1088932 SART3_CAEEL (73-962): 3.23e-124: 399: 24.26		RUXG_CAEEL (8-89): 5.67e-22: 83.4: 39.02
+	Ce
		186305 SART3_CAEEL (73-962): 3.23e-124: 399: 24.26		O18694_CAEEL (2-93): 7.33e-22: 83.4: 23.66
+	Ce
		1088926 SART3_CAEEL (73-962): 3.23e-124: 399: 24.26		Q95XD4_CAEEL (15-89): 9.46e-20: 78.5: 33.33
+	Hs
		928016 CRNL1_HUMAN (36-683): 9.67e-110: 360: 14.35		RSMN_HUMAN (8-96): 2.99e-25: 96.1: 28.57
+	Hs
		539141 CRNL1_HUMAN (36-683): 9.67e-110: 360: 14.35		RSMB_HUMAN (8-96): 5.05e-25: 95.7: 28.57
+	Hs
		912106 CRNL1_HUMAN (36-683): 9.67e-110: 360: 14.35		RUXG_HUMAN (8-90): 4.16e-24: 88.8: 32.53
+	Hs
		68456 CRNL1_HUMAN (36-683): 9.67e-110: 360: 14.35		RUXGL_HUMAN (8-90): 2.38e-22: 84.2: 31.33
+	Hs
		300046 PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10		RSMB_HUMAN (8-96): 5.05e-25: 95.7: 28.57
+	Hs
		300100 PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10		RUXG_HUMAN (8-90): 4.16e-24: 88.8: 32.53
+	Hs
		167651 PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10		LSM1_HUMAN (14-101): 1.32e-21: 84.2: 29.55
+	Hs
		68390 PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10		RUXGL_HUMAN (8-90): 2.38e-22: 84.2: 31.33