Interactor 1: SUZ12 (Q15022)
Polycomb protein SUZ12 (Chromatin precipitated E2F target 9 protein) (ChET 9 protein) (Joined to JAZF1 protein) (Suppressor of zeste 12 protein homolog)
Gene: SUZ12

Interactor 2: EZH1 (Q92800)
Histone-lysine N-methyltransferase EZH1 (EC 2.1.1.356) (ENX-2) (Enhancer of zeste homolog 1)
Gene: EZH1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 20075857, 24457600, 28514442, 27705803, 27634302, 31281901, 24981860, 33961781, 19026781, 19026780
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PRC2_HTH_1~VEFS-Box, VEFS-Box~preSET_CXC, SET~VEFS-Box
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0035098 - ESC/E(Z) complex
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 739
Hs

1 747
+ Mm
+ Mm
+ Hs
+ Mm
+ Dm
+ Mm
+ Hs
+ At
+ At
+ At
+ At

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Last updated: 15 Jul 2024