HitPredict

Interactor 1: OVOLH (G5EDU6)
Transcription factor ovo-like homolog lin-48 (Abnormal cell lineage protein 48)
Gene: lin-48

Interactor 2: NH114 (G5EEM0)
Nuclear hormone receptor 114
Gene: nhr-114

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 280 Ce			1 418
+	Hs
		368935 ZN182_HUMAN (65-279): 4.68e-84: 265: 19.18		ESR1_HUMAN (7-417): 1.23e-90: 287: 21.96
+	Ce
		106392 OVOLH_CAEEL (1-280): 3.03e-82: 250: 100.00		NHR49_CAEEL (13-409): 1.14e-94: 294: 24.88
+	Ce
		106401 OVOLH_CAEEL (1-280): 3.03e-82: 250: 100.00		Q86PI8_CAEEL (1-287): 1.68e-92: 282: 99.65
+	Hs
		563312 ZNF16_HUMAN (9-214): 1.95e-76: 247: 21.74		ESR2_HUMAN (2-406): 1.91e-89: 282: 23.25
+	Ce
		106394 OVOLH_CAEEL (1-280): 3.03e-82: 250: 100.00		NHR22_CAEEL (2-406): 1.82e-85: 273: 22.49
+	Ce
		106395 OVOLH_CAEEL (1-280): 3.03e-82: 250: 100.00		NHR31_CAEEL (2-411): 1.41e-82: 265: 24.40
+	Hs
		368937 ZKSC1_HUMAN (30-279): 3.64e-58: 196: 17.42		ESR1_HUMAN (7-417): 1.23e-90: 287: 21.96
+	Hs
		782644 ZKSC3_HUMAN (144-278): 7.23e-47: 165: 25.85		HNF4A_HUMAN (4-413): 1.1e-90: 283: 21.95
+	Hs
		368936 ZNF24_HUMAN (187-278): 7.84e-25: 103: 21.15		ESR1_HUMAN (7-417): 1.23e-90: 287: 21.96
+	Hs
		563649 ZNF24_HUMAN (187-278): 7.84e-25: 103: 21.15		ESR2_HUMAN (2-406): 1.91e-89: 282: 23.25
+	Hs
		782683 ZN629_HUMAN (2-213): 6.06e-19: 88.3: 12.34		HNF4A_HUMAN (4-413): 1.1e-90: 283: 21.95
+	Hs
		1055261 ZN629_HUMAN (2-213): 6.06e-19: 88.3: 12.34		HNF4G_HUMAN (7-408): 8.47e-89: 276: 22.39
+	Hs
		311997 ZBT7A_HUMAN (135-209): 2.61e-10: 62.4: 40.00		ESR1_HUMAN (7-417): 1.23e-90: 287: 21.96
+	Hs
		883297 PRD15_HUMAN (135-249): 1.39e-11: 66.6: 30.89		ESR2_HUMAN (2-406): 1.91e-89: 282: 23.25
+	Hs
		824095 GFI1B_HUMAN (114-214): 1.46e-11: 65.5: 33.66		NR2C2_HUMAN (1-406): 2.97e-88: 281: 17.39
+	Hs
		369512 ZBT17_HUMAN (121-209): 2.92e-09: 59.3: 34.83		ESR1_HUMAN (7-417): 1.23e-90: 287: 21.96
+	Hs
		312080 ZBT7A_HUMAN (135-209): 2.61e-10: 62.4: 40.00		ESR2_HUMAN (2-406): 1.91e-89: 282: 23.25
+	Hs
		62508 ZN316_HUMAN (135-209): 1.53e-09: 60.5: 34.67		ESR2_HUMAN (2-406): 1.91e-89: 282: 23.25
+	Hs
		1024294 ZBT17_HUMAN (121-209): 2.92e-09: 59.3: 34.83		ESR2_HUMAN (2-406): 1.91e-89: 282: 23.25