HitPredict

Interactor 1: RB3GP (Q15042)
Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP)
Gene: RAB3GAP1

Interactor 2: RBGPR (Q9H2M9)
Rab3 GTPase-activating protein non-catalytic subunit (RGAP-iso) (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit)
Gene: RAB3GAP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.55	0.585

The method score is based on:

Property	Details
Experiments	35271311, 24885147
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005096 - GTPase activator activity GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0031267 - small GTPase binding GO:0032991 - protein-containing complex and 5 others more... GO:0043087 - regulation of GTPase activity GO:0097051 - establishment of protein localization to endoplasmic reticulum membrane GO:1903061 - positive regulation of protein lipidation GO:1903373 - positive regulation of endoplasmic reticulum tubular network organization GO:2000786 - positive regulation of autophagosome assembly
Homologous interactions	0

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Last updated: 15 Jul 2024