Protein: ADNP
Activity-dependent neuroprotector homeobox protein (Activity-dependent neuroprotective protein)

Gene: ADNP
Organism: Homo sapiens
Interactions: 190
UniProt ID: Q9H2P0

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003682 - chromatin binding
GO:0005507 - copper ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

373127

MYC
Myc proto-oncogene protein

5

3

High-throughput

0.915

High

1097553

CBX3
Chromobox protein homolog 3

9

10

Small-scale

0.756

High

1132970

CHD4
Chromodomain-helicase-DNA-binding protein 4

8

5

Small-scale

0.743

High

1014199

CBX1
Chromobox protein homolog 1

6

10

Small-scale

0.737

High

853405

CBX5
Chromobox protein homolog 5

4

10

Small-scale

0.697

High

998798

H31
Histone H3.1

4

4

High-throughput

0.676

High

991707

DYL1
Dynein light chain 1, cytoplasmic

3

1

High-throughput

0.675

High

1432101

DAXX
Death domain-associated protein 6

4

0

High-throughput

0.667

High

1356768

HDAC7
Histone deacetylase 7

3

1

High-throughput

0.667

High

1385564

ZN524
Zinc finger protein 524

3

3

High-throughput

0.667

High

911375

IMA5
Importin subunit alpha-5

3

4

High-throughput

0.662

High

600569

ZSC20
Zinc finger and SCAN domain-containing protein 20

3

0

High-throughput

0.638

High

1110072

HDAC1
Histone deacetylase 1

2

1

High-throughput

0.628

High

1432098

ZN581
Zinc finger protein 581

2

5

High-throughput

0.628

High

406632

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.618

High

1310127

MGAP
MAX gene-associated protein

1

1

High-throughput

0.618

High

1405561

TBX5
T-box transcription factor TBX5

1

1

High-throughput

0.618

High

502125

H2AZ
Histone H2A.Z

2

1

High-throughput

0.611

High

1432091

ZN644
Zinc finger protein 644

2

1

High-throughput

0.611

High

1432100

ZMYM2
Zinc finger MYM-type protein 2

2

2

High-throughput

0.611

High

1233793

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.602

High

1099777

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

2

1

High-throughput

0.601

High

260444

BRD4
Bromodomain-containing protein 4

2

2

High-throughput

0.584

High

414601

P53
Cellular tumor antigen p53

2

0

High-throughput

0.559

High

558399

XRCC6
X-ray repair cross-complementing protein 6

2

0

High-throughput

0.559

High

1314415

SLX4
Structure-specific endonuclease subunit SLX4

2

0

High-throughput

0.559

High

1432105

PNMA2
Paraneoplastic antigen Ma2

2

1

High-throughput

0.549

High

330312

VENTX
Homeobox protein VENTX

1

0

High-throughput

0.546

High

133130

FOXE1
Forkhead box protein E1

1

5

High-throughput

0.536

High

179080

IMA6
Importin subunit alpha-6

1

4

High-throughput

0.536

High

221966

FOXS1
Forkhead box protein S1

1

4

High-throughput

0.536

High

340938

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

1

High-throughput

0.536

High

931107

HSP72
Heat shock-related 70 kDa protein 2

1

1

High-throughput

0.536

High

937652

FOXG1
Forkhead box protein G1

1

4

High-throughput

0.536

High

1029753

FOXK2
Forkhead box protein K2

1

3

High-throughput

0.536

High

1065424

SSRP1
FACT complex subunit SSRP1

1

1

High-throughput

0.536

High

1163201

H2B2E
Histone H2B type 2-E

1

2

High-throughput

0.536

High

1219751

ZMYM4
Zinc finger MYM-type protein 4

1

2

High-throughput

0.536

High

1387269

HDA11
Histone deacetylase 11

1

2

High-throughput

0.536

High

1390714

DYL2
Dynein light chain 2, cytoplasmic

1

1

High-throughput

0.536

High

1420496

FOXQ1
Forkhead box protein Q1

1

4

High-throughput

0.536

High

1432093

PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

1

1

High-throughput

0.536

High

1432097

FOXJ2
Forkhead box protein J2

1

4

High-throughput

0.536

High

74600

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.513

High

347319

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

384545

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.513

High

542219

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

553069

PIP
Prolactin-inducible protein

1

0

High-throughput

0.513

High

714418

PML
Protein PML

1

0

High-throughput

0.513

High

788196

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.513

High

920715

NUBP1
Cytosolic Fe-S cluster assembly factor NUBP1

1

0

High-throughput

0.513

High

925750

SC24C
Protein transport protein Sec24C

1

0

High-throughput

0.513

High

1035454

ODO1
2-oxoglutarate dehydrogenase complex component E1

1

0

High-throughput

0.513

High

1104482

ILK
Scaffold protein ILK

1

0

High-throughput

0.513

High

1111867

TRA2A
Transformer-2 protein homolog alpha

1

0

High-throughput

0.513

High

1116585

FHL3
Four and a half LIM domains protein 3

1

0

High-throughput

0.513

High

1134719

NUMA1
Nuclear mitotic apparatus protein 1

1

0

High-throughput

0.513

High

1150253

TEAD2
Transcriptional enhancer factor TEF-4

1

0

High-throughput

0.513

High

1153669

ZKSC8
Zinc finger protein with KRAB and SCAN domains 8

1

0

High-throughput

0.513

High

1331853

SYT2
Synaptotagmin-2

1

0

High-throughput

0.513

High

1150081

MARE2
Microtubule-associated protein RP/EB family member 2

1

2

High-throughput

0.489

High

1432099

RRBP1
Ribosome-binding protein 1

1

1

High-throughput

0.489

High

143247

NFIB
Nuclear factor 1 B-type

1

6

High-throughput

0.479

High

154750

ARI1A
AT-rich interactive domain-containing protein 1A

1

1

Small-scale

0.479

High

244109

ZN292
Zinc finger protein 292

1

1

High-throughput

0.479

High

246943

KDM1A
Lysine-specific histone demethylase 1A

1

2

High-throughput

0.479

High

277815

H2AY
Core histone macro-H2A.1

1

2

High-throughput

0.479

High

285472

EED
Polycomb protein EED

1

3

High-throughput

0.479

High

339853

KLF8
Krueppel-like factor 8

1

3

High-throughput

0.479

High

355598

NSD2
Histone-lysine N-methyltransferase NSD2

1

1

Small-scale

0.479

High

396928

ESR1
Estrogen receptor

1

3

High-throughput

0.479

High

449788

H2B1J
Histone H2B type 1-J

1

2

High-throughput

0.479

High

474281

NFIC
Nuclear factor 1 C-type

1

6

High-throughput

0.479

High

520368

ANDR
Androgen receptor

1

3

High-throughput

0.479

High

537895

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

589662

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

591836

H2AX
Histone H2AX

1

2

High-throughput

0.479

High

607101

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

625620

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.479

High

675672

TYY1
Transcriptional repressor protein YY1

1

3

High-throughput

0.479

High

765027

CTNB1
Catenin beta-1

1

5

Small-scale

0.479

High

765882

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.479

High

834052

HNF4A
Hepatocyte nuclear factor 4-alpha

1

2

High-throughput

0.479

High

855516

ATRX
Transcriptional regulator ATRX

1

8

Small-scale

0.479

High

862450

YAP1
Transcriptional coactivator YAP1

1

1

High-throughput

0.479

High

872739

SOX2
Transcription factor SOX-2

1

3

Small-scale

0.479

High

879458

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

887217

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.479

High

903480

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

7

Small-scale

0.479

High

965236

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.479

High

981087

H2B1C
Histone H2B type 1-C/E/F/G/I

1

2

High-throughput

0.479

High

998018

CSK21
Casein kinase II subunit alpha

1

2

High-throughput

0.479

High

1017203

H33
Histone H3.3

1

4

High-throughput

0.479

High

1040921

MECOM
Histone-lysine N-methyltransferase MECOM

1

1

High-throughput

0.479

High

1088009

NFIA
Nuclear factor 1 A-type

1

7

High-throughput

0.479

High

1088562

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

5

High-throughput

0.479

High

1091154

FOXC1
Forkhead box protein C1

1

4

High-throughput

0.479

High

1094734

CAF1A
Chromatin assembly factor 1 subunit A

1

1

High-throughput

0.479

High

1094812

CAF1B
Chromatin assembly factor 1 subunit B

1

2

High-throughput

0.479

High

1096814

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

1106378

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

1

High-throughput

0.479

High

1133654

NFIX
Nuclear factor 1 X-type

1

6

High-throughput

0.479

High

1141303

BRD3
Bromodomain-containing protein 3

1

2

High-throughput

0.479

High

1216486

AHDC1
Transcription factor Gibbin

1

1

High-throughput

0.479

High

1235078

ADNP2
Activity-dependent neuroprotector homeobox protein 2

1

4

High-throughput

0.479

High

1240775

PMF1
Polyamine-modulated factor 1

1

1

High-throughput

0.479

High

1255504

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1277234

POGZ
Pogo transposable element with ZNF domain

1

1

High-throughput

0.479

High

1278805

HDGR2
Hepatoma-derived growth factor-related protein 2

1

2

High-throughput

0.479

High

1329867

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

High-throughput

0.479

High

1332179

SCAI
Protein SCAI

1

1

High-throughput

0.479

High

1337837

CSK23
Casein kinase II subunit alpha 3

1

2

High-throughput

0.479

High

1347551

SMRC2
SWI/SNF complex subunit SMARCC2

1

3

Small-scale

0.479

High

1367253

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1394503

NSL1
Kinetochore-associated protein NSL1 homolog

1

1

High-throughput

0.479

High

1395204

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

1

High-throughput

0.479

High

1401387

CIC
Protein capicua homolog

1

1

High-throughput

0.479

High

1404755

RING2
E3 ubiquitin-protein ligase RING2

1

4

High-throughput

0.479

High

1418391

PCGF6
Polycomb group RING finger protein 6

1

2

High-throughput

0.479

High

1428966

WWTR1
WW domain-containing transcription regulator protein 1

1

1

High-throughput

0.479

High

1429538

MIS12
Protein MIS12 homolog

1

1

High-throughput

0.479

High

1432089

DSN1
Kinetochore-associated protein DSN1 homolog

1

1

High-throughput

0.479

High

1432095

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.479

High

718626

CDC27
Cell division cycle protein 27 homolog

1

0

High-throughput

0.460

High

129417

MEN1
Menin

1

0

High-throughput

0.458

High

157842

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

316004

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

346318

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

412597

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

572210

TRI27
Zinc finger protein RFP

1

0

Small-scale

0.458

High

696480

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

905133

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

935122

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

980312

H4
Histone H4

1

0

High-throughput

0.458

High

995261

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.458

High

995815

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

1054788

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.458

High

1114276

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1140843

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1276778

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1287016

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

0

Small-scale

0.458

High

1289619

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1313424

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1364247

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.458

High

1380965

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

0

High-throughput

0.458

High

1416443

PHF7
E3 ubiquitin-protein ligase PHF7

1

0

High-throughput

0.458

High

1417468

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

1432090

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1432092

LN28A
Protein lin-28 homolog A

1

0

Small-scale

0.458

High

1432096

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1432102

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

430350

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

600375

ZNF24
Zinc finger protein 24

1

2

High-throughput

0.445

High

911103

IMA1
Importin subunit alpha-1

1

4

High-throughput

0.445

High

619108

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

1

High-throughput

0.437

High

1212461

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

1

High-throughput

0.437

High

1430579

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.437

High

379307

IGHG1
Immunoglobulin heavy constant gamma 1

1

0

High-throughput

0.426

High

1006703

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.426

High

1111263

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.426

High

1404392

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.426

High

142618

IMA3
Importin subunit alpha-3

1

4

High-throughput

0.408

High

1162043

H31T
Histone H3.1t

1

4

High-throughput

0.408

High

1144796

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

3

0

High-throughput

0.347

High

1432103

DPOG2
DNA polymerase subunit gamma-2

3

0

High-throughput

0.345

High

166191

AIM2
Interferon-inducible protein AIM2

1

0

High-throughput

0.279

Low

187795

EIF3D
Eukaryotic translation initiation factor 3 subunit D

1

0

High-throughput

0.279

Low

317750

NOL4
Nucleolar protein 4

1

0

High-throughput

0.279

Low

773978

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.279

Low

846788

GRK6
G protein-coupled receptor kinase 6

1

0

High-throughput

0.279

Low

1139384

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.279

Low

1331606

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

0

High-throughput

0.279

Low

1367904

THRSP
Thyroid hormone-inducible hepatic protein

1

0

High-throughput

0.279

Low

1402711

TCPQM
T-complex protein 1 subunit theta-like 2

1

0

High-throughput

0.279

Low

1432106

PCDBF
Protocadherin beta-15

1

0

High-throughput

0.279

Low

984975

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.269

Low

1428349

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

0

High-throughput

0.265

Low

332113

MRP6
ATP-binding cassette sub-family C member 6

1

0

Small-scale

0.249

Low

769151

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1292972

AROS
Active regulator of SIRT1

1

0

High-throughput

0.249

Low

1332325

CC71L
Coiled-coil domain-containing protein 71L

1

0

High-throughput

0.249

Low

1337378

FXL13
F-box and leucine-rich repeat protein 13

1

0

Small-scale

0.249

Low

1415864

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.249

Low

1432088

TXNIP
Thioredoxin-interacting protein

1

0

Small-scale

0.249

Low

1432094

ANLN
Anillin

1

0

High-throughput

0.249

Low

1432104

TF3C4
General transcription factor 3C polypeptide 4

1

0

High-throughput

0.249

Low

337813

SGPL1
Sphingosine-1-phosphate lyase 1

1

0

High-throughput

0.232

Low

1155101

UT2
Urea transporter 2

1

0

High-throughput

0.232

Low

1253659

PKHG7
Pleckstrin homology domain-containing family G member 7

1

0

High-throughput

0.232

Low

1363446

S39A7
Zinc transporter SLC39A7

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025