HitPredict

Interactor 1: ACAP2 (Q15057)
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2)
Gene: ACAP2

Interactor 2: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34315543
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PX, PH~RA
Common GO terms	GO:0032456 - endocytic recycling
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 778 Hs			1 541
+	Hs
		63080 RHG42_HUMAN (4-426): 2.23e-81: 280: 20.27		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		1296897 TANC1_HUMAN (89-768): 2.33e-63: 233: 13.05		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		1296866 ANR27_HUMAN (8-772): 7.2e-63: 230: 14.52		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Mm
		110605 AGAP2_MOUSE (632-698): 3.64e-12: 72.2: 28.36		H3BL28_MOUSE (40-375): 4.97e-42: 163: 14.43
+	Mm
		1112600 AGAP2_MOUSE (632-698): 3.64e-12: 72.2: 28.36		Q7TN74_MOUSE (40-375): 2.98e-41: 161: 14.43
+	Mm
		1112594 AGAP2_MOUSE (632-698): 3.64e-12: 72.2: 28.36		NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98
+	Mm
		88367 AGAP2_MOUSE (632-698): 3.64e-12: 72.2: 28.36		SHAN1_MOUSE (43-183): 5.48e-32: 133: 30.28
+	Mm
		1112608 AGAP2_MOUSE (632-698): 3.64e-12: 72.2: 28.36		SHAN2_MOUSE (43-147): 1.26e-28: 123: 39.05
+	Hs
		1300695 AGAP1_HUMAN (300-634): 6.59e-24: 109: 22.85		MAGI1_HUMAN (2-334): 3.18e-13: 74.9: 17.51
+	Hs
		1138562 AGAP7_HUMAN (601-697): 1.74e-13: 76: 29.29		SHAN3_HUMAN (44-148): 1.57e-21: 101: 37.14
+	Mm
		1112568 AGAP2_MOUSE (632-698): 3.64e-12: 72.2: 28.36		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Hs
		1200078 ASAP3_HUMAN (149-748): 5.08e-20: 97.4: 12.58		NHRF4_HUMAN (8-146): 1.15e-11: 69.2: 21.99