Protein: ASH1L
Histone-lysine N-methyltransferase ASH1L (EC 2.1.1.359) (EC 2.1.1.367) (ASH1-like protein) (huASH1) (Absent small and homeotic disks protein 1 homolog) (Lysine N-methyltransferase 2H)

Gene: ASH1L
Organism: Homo sapiens
Interactions: 58
UniProt ID: Q9NR48

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0001501 - skeletal system development
GO:0002674 - negative regulation of acute inflammatory response
GO:0003677 - DNA binding
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1066512

RBBP4
Histone-binding protein RBBP4

3

20

Small-scale

0.839

High

998846

H31
Histone H3.1

2

20

Small-scale

0.778

High

179253

ARC1B
Actin-related protein 2/3 complex subunit 1B

2

11

High-throughput

0.776

High

1447965

MO4L1
Mortality factor 4-like protein 1

7

5

Small-scale

0.746

High

1159019

RBBP7
Histone-binding protein RBBP7

2

20

Small-scale

0.737

High

1136863

MO4L2
Mortality factor 4-like protein 2

5

5

Small-scale

0.712

High

833783

KDM5C
Lysine-specific demethylase 5C

1

15

High-throughput

0.691

High

1372315

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.665

High

1413132

THAP7
THAP domain-containing protein 7

3

0

High-throughput

0.638

High

868389

CDX1
Homeobox protein CDX-1

2

9

High-throughput

0.628

High

1429101

NXF2
Nuclear RNA export factor 2

2

1

High-throughput

0.628

High

260501

BRD4
Bromodomain-containing protein 4

1

20

High-throughput

0.618

High

1017237

H33
Histone H3.3

1

20

Small-scale

0.618

High

1338986

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.618

High

1447966

BRPF3
Bromodomain and PHD finger-containing protein 3

1

20

High-throughput

0.618

High

423264

A4
Amyloid-beta precursor protein

2

3

High-throughput

0.608

High

391480

FRIL
Ferritin light chain

2

1

High-throughput

0.549

High

171108

VP26C
Vacuolar protein sorting-associated protein 26C

1

2

High-throughput

0.541

High

191826

MAGB2
Melanoma-associated antigen B2

1

8

High-throughput

0.536

High

625648

CSK22
Casein kinase II subunit alpha'

1

6

High-throughput

0.536

High

659605

CRCM
Colorectal mutant cancer protein

1

2

High-throughput

0.536

High

848726

MAGA9
Melanoma-associated antigen 9

1

8

High-throughput

0.536

High

855233

NOP2
28S rRNA

1

2

High-throughput

0.536

High

960908

RL15
Large ribosomal subunit protein eL15

1

2

High-throughput

0.536

High

978748

RL23A
Large ribosomal subunit protein uL23

1

6

High-throughput

0.536

High

1095948

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

1

High-throughput

0.536

High

1151211

OASL
2'-5'-oligoadenylate synthase-like protein

1

5

High-throughput

0.536

High

1447964

GID8
Glucose-induced degradation protein 8 homolog

1

1

High-throughput

0.536

High

1446169

PAR6A
Partitioning defective 6 homolog alpha

1

0

High-throughput

0.513

High

177720

SMAD7
Mothers against decapentaplegic homolog 7

1

11

High-throughput

0.508

High

720725

OXYR
Oxytocin receptor

1

1

High-throughput

0.494

High

860020

RL28
Large ribosomal subunit protein eL28

1

2

High-throughput

0.489

High

1127510

FGFP1
Fibroblast growth factor-binding protein 1

1

2

High-throughput

0.489

High

1290047

PNM8A
Paraneoplastic antigen-like protein 8A

1

2

High-throughput

0.489

High

157899

CTRO
Citron Rho-interacting kinase

1

6

High-throughput

0.479

High

212336

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

1

High-throughput

0.479

High

229086

AKAP8
A-kinase anchor protein 8

1

1

Small-scale

0.479

High

353576

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.479

High

613197

EGR1
Early growth response protein 1

1

4

High-throughput

0.479

High

809866

RS19
Small ribosomal subunit protein eS19

1

5

High-throughput

0.479

High

959984

RS3A
Small ribosomal subunit protein eS1

1

5

High-throughput

0.479

High

978331

RHOB
Rho-related GTP-binding protein RhoB

1

3

High-throughput

0.479

High

981712

RAN
GTP-binding nuclear protein Ran

1

9

High-throughput

0.479

High

1114397

CUL3
Cullin-3

1

9

High-throughput

0.479

High

1141960

EEA1
Early endosome antigen 1

1

6

High-throughput

0.479

High

1357571

DCAF4
DDB1- and CUL4-associated factor 4

1

1

High-throughput

0.479

High

1143278

PLEC
Plectin

1

6

High-throughput

0.470

High

1199710

KLH22
Kelch-like protein 22

1

2

High-throughput

0.445

High

106702

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

1447967

G3BP2
Ras GTPase-activating protein-binding protein 2

1

6

High-throughput

0.437

High

640299

EPHA1
Ephrin type-A receptor 1

1

2

High-throughput

0.417

High

58945

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

2

High-throughput

0.407

High

1397250

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.279

Low

1411926

SIKE1
Suppressor of IKBKE 1

1

0

High-throughput

0.279

Low

1447968

CLC11
C-type lectin domain family 11 member A

1

0

High-throughput

0.279

Low

1131237

MESD
LRP chaperone MESD

1

0

High-throughput

0.269

Low

914217

EFNA3
Ephrin-A3

1

0

High-throughput

0.249

Low

947060

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025