Interactor 1: RAGE (Q15109)
Advanced glycosylation end product-specific receptor (Receptor for advanced glycosylation end products)
Gene: AGER

Interactor 2: TLR9 (Q9NR96)
Toll-like receptor 9 (CD antigen CD289)
Gene: TLR9

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 17417641
Identification Methods anti tag coimmunoprecipitation, amplified luminescent proximity homogeneous assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~ig, Ig_3~LRR_8
Common GO terms GO:0001774 - microglial cell activation
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0016324 - apical plasma membrane
GO:0032722 - positive regulation of chemokine production
and 5 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 404
Hs

1 1032
+ Dr
+ Dr
+ Dr
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Mm

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Last updated: 15 Jul 2024