Interactor 1: SMU1 (G5EEG7)
Smu-1 suppressor of mec-8 and unc-52 protein (Smu1) (Suppressor of Mec and Unc defects 1)
Gene: smu-1

Interactor 2: SMU2 (Q9N4U5)
Smu-2 suppressor of mec-8 and unc-52 protein (RED homolog) (Suppressor of Mec and Unc defects 2)
Gene: smu-2

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.883

The method score is based on:

Property Details
Experiments 19123269, 15254247, 27150041
Identification Methods two hybrid, affinity chromatography technology, x-ray crystallography, pull down, surface plasmon resonance, molecular sieving, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LisH_TPL~RED_N
Common GO terms GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0000398 - mRNA splicing, via spliceosome
GO:0002119 - nematode larval development
GO:0005634 - nucleus
GO:0007638 - mechanosensory behavior
and 4 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 510
Ce

1 547
+ Hs
+ Dm
+ Hs
+ At

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Last updated: 15 Jul 2024