Protein: EXOC2
Exocyst complex component 2 (Exocyst complex component Sec5)

Gene: EXOC2
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q96KP1

Gene Ontology (top 5):
GO:0000145 - exocyst
GO:0000281 - mitotic cytokinesis
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006887 - exocytosis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1396215

EXOC1
Exocyst complex component 1

6

2

Small-scale

0.948

High

1315117

EXOC8
Exocyst complex component 8

5

2

Small-scale

0.930

High

539900

RALB
Ras-related protein Ral-B

5

8

Small-scale

0.925

High

539838

RALA
Ras-related protein Ral-A

5

9

Small-scale

0.906

High

1382568

EXOC4
Exocyst complex component 4

4

2

Small-scale

0.895

High

262288

SCN2B
Sodium channel regulatory subunit beta-2

3

4

High-throughput

0.839

High

252901

EXOC3
Exocyst complex component 3

4

3

High-throughput

0.697

High

1347241

EXOC6
Exocyst complex component 6

3

3

High-throughput

0.675

High

774562

BASI
Basigin

3

5

High-throughput

0.667

High

1396221

TBK1
Serine/threonine-protein kinase TBK1

3

2

Small-scale

0.657

High

630184

ACM3
Muscarinic acetylcholine receptor M3

2

2

High-throughput

0.628

High

665325

EDNRB
Endothelin receptor type B

2

3

High-throughput

0.628

High

771208

APJ
Apelin receptor

2

6

High-throughput

0.628

High

1396225

EXC6B
Exocyst complex component 6B

2

3

High-throughput

0.628

High

976487

RB11A
Ras-related protein Rab-11A

1

3

High-throughput

0.618

High

978227

RHOB
Rho-related GTP-binding protein RhoB

1

7

High-throughput

0.618

High

1396204

EXOC2
Exocyst complex component 2

1

2

Small-scale

0.618

High

1396223

EXOC7
Exocyst complex component 7

1

2

High-throughput

0.618

High

699573

IL1R2
Interleukin-1 receptor type 2

2

0

High-throughput

0.602

High

388278

GLPA
Glycophorin-A

2

1

High-throughput

0.601

High

638503

FPR1
fMet-Leu-Phe receptor

2

8

High-throughput

0.601

High

1101634

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

2

11

High-throughput

0.601

High

1396220

SRGEF
Secretion-regulating guanine nucleotide exchange factor

2

0

Small-scale

0.581

High

396729

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

1126745

BECN1
Beclin-1

2

0

Small-scale

0.559

High

842833

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

1

High-throughput

0.541

High

133301

P2Y10
Putative P2Y purinoceptor 10

1

12

High-throughput

0.536

High

137263

EXOC5
Exocyst complex component 5

1

2

High-throughput

0.536

High

1396229

NPTN
Neuroplastin

1

5

High-throughput

0.536

High

182733

GP182
G-protein coupled receptor 182

1

12

High-throughput

0.536

High

719829

V2R
Vasopressin V2 receptor

1

4

High-throughput

0.536

High

760489

SDC2
Syndecan-2

1

1

High-throughput

0.536

High

956981

CXCR4
C-X-C chemokine receptor type 4

1

9

High-throughput

0.536

High

990609

1433Z
14-3-3 protein zeta/delta

1

2

High-throughput

0.536

High

1142147

P2RY6
P2Y purinoceptor 6

1

12

High-throughput

0.536

High

1290445

EX3L1
Exocyst complex component 3-like protein

1

3

High-throughput

0.536

High

1291660

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

1

High-throughput

0.536

High

1291868

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

10

High-throughput

0.536

High

1396206

CDC5L
Cell division cycle 5-like protein

1

3

High-throughput

0.536

High

1396228

GPR45
Probable G-protein coupled receptor 45

1

4

High-throughput

0.536

High

718450

CD6
T-cell differentiation antigen CD6

1

0

High-throughput

0.513

High

749261

CD70
CD70 antigen

1

0

High-throughput

0.513

High

1053051

VMAT2
Synaptic vesicular amine transporter

1

0

High-throughput

0.513

High

1132574

FXYD3
FXYD domain-containing ion transport regulator 3

1

0

High-throughput

0.513

High

1178786

AAK1
AP2-associated protein kinase 1

1

0

High-throughput

0.513

High

1396207

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

0

High-throughput

0.513

High

1396224

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

0

High-throughput

0.513

High

1217275

VPS53
Vacuolar protein sorting-associated protein 53 homolog

1

2

Small-scale

0.481

High

242609

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

279204

ULK1
Serine/threonine-protein kinase ULK1

1

1

Small-scale

0.479

High

412449

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

845469

PE2R3
Prostaglandin E2 receptor EP3 subtype

1

4

High-throughput

0.479

High

851086

LPAR6
Lysophosphatidic acid receptor 6

1

11

High-throughput

0.479

High

895209

5HT6R
5-hydroxytryptamine receptor 6

1

1

Small-scale

0.479

High

1138519

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1178312

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

1353408

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

1

1

Small-scale

0.479

High

1396210

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

1396218

TLS1
Splicing factor C9orf78

1

2

High-throughput

0.479

High

1396219

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1396205

RANB9
Ran-binding protein 9

1

0

High-throughput

0.460

High

363722

EGFR
Epidermal growth factor receptor

1

0

Small-scale

0.458

High

754942

H2B1B
Histone H2B type 1-B

1

0

High-throughput

0.458

High

980154

H4
Histone H4

1

0

High-throughput

0.458

High

1106665

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

1114017

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1229632

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1252936

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

Small-scale

0.458

High

1337308

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

0

Small-scale

0.458

High

1365934

RUBIC
Run domain Beclin-1-interacting and cysteine-rich domain-containing protein

1

0

Small-scale

0.458

High

1396208

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

1396213

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.457

High

166395

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

1

High-throughput

0.445

High

616789

SDC1
Syndecan-1

1

1

High-throughput

0.445

High

944034

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.445

High

106475

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

589430

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

696236

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

768915

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

1255105

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1367038

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

1393601

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.437

High

1396209

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.437

High

171558

S27A2
Long-chain fatty acid transport protein 2

1

0

High-throughput

0.426

High

564225

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

935011

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.426

High

1209525

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1396214

S22AB
Solute carrier family 22 member 11

1

0

High-throughput

0.426

High

1396226

NOC2L
Nucleolar complex protein 2 homolog

1

0

High-throughput

0.426

High

1396212

WDR76
WD repeat-containing protein 76

2

0

High-throughput

0.305

High

1329161

ESX1
Homeobox protein ESX1

1

0

High-throughput

0.282

High

324028

CSTN1
Calsyntenin-1

1

0

High-throughput

0.279

Low

1111198

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.279

Low

1396227

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.279

Low

372858

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

419139

H2A1B
Histone H2A type 1-B/E

1

0

High-throughput

0.249

Low

1231137

SCAR3
Scavenger receptor class A member 3

1

0

High-throughput

0.249

Low

1368056

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.249

Low

1396216

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

0

High-throughput

0.249

Low

1396217

AATF
Protein AATF

1

0

High-throughput

0.249

Low

1396222

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

Small-scale

0.249

Low

1396211

ZDH11
Palmitoyltransferase ZDHHC11

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025