HitPredict

Interactor 1: PLEC (Q15149)
Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)
Gene: PLEC

Interactor 2: CEP63 (Q96MT8)
Centrosomal protein of 63 kDa (Cep63)
Gene: CEP63

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35709258
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4684 Hs			1 703
+	Hs
		724839 PLEC_HUMAN (1-4684): 0: 1783: 100.00		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		1068548 PLEC_HUMAN (1-4684): 0: 1783: 100.00		GRDN_HUMAN (150-697): 6.94e-17: 87.5: 12.91
+	Hs
		148841 PLEC_HUMAN (1-4684): 0: 1783: 100.00		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		1068617 PLEC_HUMAN (1-4684): 0: 1783: 100.00		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Mm
		93578 PLEC_MOUSE (1-4684): 0: 1747: 93.29		DESP_MOUSE (59-550): 4.18e-09: 62.5: 18.91
+	Hs
		148722 ACTN3_HUMAN (166-893): 2.36e-146: 484: 25.79		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		148330 SPTB1_HUMAN (151-2274): 6.68e-124: 442: 17.12		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		521484 ACTN1_HUMAN (153-876): 1.96e-112: 384: 23.94		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		148339 ACTN1_HUMAN (153-876): 1.96e-112: 384: 23.94		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		164656 SPTN2_HUMAN (1390-3166): 2.85e-25: 118: 12.24		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Mm
		513799 DMD_MOUSE (1215-3224): 1.33e-25: 120: 9.43		DEUP1_MOUSE (8-523): 3.71e-62: 220: 27.78
+	Hs
		963396 SPTB2_HUMAN (1531-3349): 2.4e-17: 92.7: 9.53		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Hs
		148591 EPIPL_HUMAN (3039-3941): 6.03e-42: 174: 27.75		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		885304 EPIPL_HUMAN (3039-3941): 6.03e-42: 174: 27.75		CP250_HUMAN (150-696): 7.75e-10: 64.8: 11.94
+	Hs
		164575 SPTN2_HUMAN (1390-3166): 2.85e-25: 118: 12.24		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		148142 SPTN2_HUMAN (1390-3166): 2.85e-25: 118: 12.24		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		164647 SPTN2_HUMAN (1390-3166): 2.85e-25: 118: 12.24		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Hs
		724781 SPTB2_HUMAN (1531-3349): 2.4e-17: 92.7: 9.53		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		148690 SPTB2_HUMAN (1531-3349): 2.4e-17: 92.7: 9.53		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		963381 SPTB2_HUMAN (1531-3349): 2.4e-17: 92.7: 9.53		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15