Protein: AAKG3
5'-AMP-activated protein kinase subunit gamma-3 (AMPK gamma3) (AMPK subunit gamma-3)

Gene: AAKG3, PRKAG3
Organism: Homo sapiens
Interactions: 79
UniProt ID: Q9UGI9

Gene Ontology (top 5):
GO:0004679 - AMP-activated protein kinase activity
GO:0005524 - ATP binding
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

225716

AAKB2
5'-AMP-activated protein kinase subunit beta-2

7

18

Small-scale

0.966

High

1459546

AAKB1
5'-AMP-activated protein kinase subunit beta-1

5

17

Small-scale

0.928

High

930812

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

4

20

High-throughput

0.903

High

1095477

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

4

20

High-throughput

0.903

High

261889

PFD1
Prefoldin subunit 1

4

0

High-throughput

0.670

High

182203

PFD6
Prefoldin subunit 6

3

0

High-throughput

0.638

High

347979

BAG3
BAG family molecular chaperone regulator 3

2

1

High-throughput

0.611

High

1326576

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

3

1

High-throughput

0.609

High

922523

CLH2
Clathrin heavy chain 2

2

0

High-throughput

0.602

High

1186924

KR195
Keratin-associated protein 19-5

2

0

High-throughput

0.580

High

155419

PTPRT
Receptor-type tyrosine-protein phosphatase T

1

1

High-throughput

0.553

High

274795

DNJB6
DnaJ homolog subfamily B member 6

1

3

High-throughput

0.536

High

316117

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.536

High

326078

UBR5
E3 ubiquitin-protein ligase UBR5

1

2

High-throughput

0.536

High

337044

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

2

High-throughput

0.536

High

538060

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.536

High

610931

TCPA
T-complex protein 1 subunit alpha

1

3

High-throughput

0.536

High

679279

DNJB1
DnaJ homolog subfamily B member 1

1

5

High-throughput

0.536

High

723131

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

2

High-throughput

0.536

High

731675

STIP1
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.536

High

821609

TCPZ
T-complex protein 1 subunit zeta

1

3

High-throughput

0.536

High

856968

BAG6
Large proline-rich protein BAG6

1

3

High-throughput

0.536

High

876214

TCPE
T-complex protein 1 subunit epsilon

1

4

High-throughput

0.536

High

882207

TCPG
T-complex protein 1 subunit gamma

1

4

High-throughput

0.536

High

899268

TCPQ
T-complex protein 1 subunit theta

1

5

High-throughput

0.536

High

899622

TCPD
T-complex protein 1 subunit delta

1

3

High-throughput

0.536

High

912022

DGKE
Diacylglycerol kinase epsilon

1

1

High-throughput

0.536

High

931148

HSP72
Heat shock-related 70 kDa protein 2

1

4

High-throughput

0.536

High

1007326

TCPB
T-complex protein 1 subunit beta

1

4

High-throughput

0.536

High

1110421

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

4

High-throughput

0.536

High

1110584

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

3

High-throughput

0.536

High

1244384

SKI3
Superkiller complex protein 3

1

5

High-throughput

0.536

High

1277799

MYH14
Myosin-14

1

8

High-throughput

0.536

High

1290506

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

2

High-throughput

0.536

High

1365788

GCN1
Stalled ribosome sensor GCN1

1

3

High-throughput

0.536

High

1389924

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

3

High-throughput

0.536

High

1406513

ATX2
Ataxin-2

1

4

High-throughput

0.536

High

1407616

TCPH
T-complex protein 1 subunit eta

1

4

High-throughput

0.536

High

1447146

PFD4
Prefoldin subunit 4

1

1

High-throughput

0.536

High

1459544

BAG5
BAG family molecular chaperone regulator 5

1

1

High-throughput

0.536

High

1459545

CHIP
E3 ubiquitin-protein ligase CHIP

1

1

High-throughput

0.536

High

64144

CNOT1
CCR4-NOT transcription complex subunit 1

1

0

High-throughput

0.513

High

162382

PDCD5
Programmed cell death protein 5

1

0

High-throughput

0.513

High

322474

HAUS5
HAUS augmin-like complex subunit 5

1

0

High-throughput

0.513

High

913423

MSH6
DNA mismatch repair protein Msh6

1

0

High-throughput

0.513

High

963385

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.513

High

1259552

TBA1A
Tubulin alpha-1A chain

1

0

High-throughput

0.513

High

1403607

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.513

High

1404689

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.513

High

1436860

MARH7
E3 ubiquitin-protein ligase MARCHF7

1

0

High-throughput

0.513

High

1437970

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.513

High

1449785

PDRG1
p53 and DNA damage-regulated protein 1

1

0

High-throughput

0.513

High

1459543

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.513

High

799549

BRCA1
Breast cancer type 1 susceptibility protein

1

4

High-throughput

0.481

High

1453621

LMCD1
LIM and cysteine-rich domains protein 1

1

2

Small-scale

0.481

High

125910

ARVC
Splicing regulator ARVCF

1

1

High-throughput

0.479

High

273791

ATS4
A disintegrin and metalloproteinase with thrombospondin motifs 4

1

1

High-throughput

0.479

High

279230

ULK1
Serine/threonine-protein kinase ULK1

1

18

High-throughput

0.479

High

1060585

KLC1
Kinesin light chain 1

1

5

Small-scale

0.479

High

1286723

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

1

High-throughput

0.479

High

1396195

RPGR1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

1

9

High-throughput

0.479

High

384741

CRYAB
Alpha-crystallin B chain

1

0

Small-scale

0.460

High

1446274

NGRN
Neugrin

1

0

Small-scale

0.460

High

289186

PRDM1
PR domain zinc finger protein 1

1

0

High-throughput

0.458

High

1217131

PI3R6
Phosphoinositide 3-kinase regulatory subunit 6

1

0

High-throughput

0.458

High

1399242

PCFT
Proton-coupled folate transporter

1

0

High-throughput

0.458

High

1421240

ZN436
Zinc finger protein 436

1

0

High-throughput

0.458

High

992459

GBG5

1

1

High-throughput

0.437

High

841087

HELZ
Probable helicase with zinc finger domain

1

0

High-throughput

0.426

High

1017820

CCZ1B
Vacuolar fusion protein CCZ1 homolog B

1

0

High-throughput

0.279

Low

1432598

CPVL
Probable serine carboxypeptidase CPVL

1

0

High-throughput

0.279

Low

674

A0A087WVX1
Family with sequence similarity 228 member B

1

0

High-throughput

0.249

Low

91516

AJM1
Apical junction component 1 homolog

1

0

High-throughput

0.249

Low

185044

SPTC2
Serine palmitoyltransferase 2

1

0

High-throughput

0.249

Low

257579

TI17B
Mitochondrial import inner membrane translocase subunit Tim17-B

1

0

High-throughput

0.249

Low

257684

PRAF2
PRA1 family protein 2

1

0

High-throughput

0.249

Low

505464

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.249

Low

1214215

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.249

Low

1454891

DPM3
Dolichol-phosphate mannosyltransferase subunit 3

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025