HitPredict

Interactor 1: Q15156 (Q15156)
PML-RAR protein
Gene: PML-RAR

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23518351
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0035259 - nuclear glucocorticoid receptor binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 797 Hs			1 2514
+	Hs
		740633 PPARG_HUMAN (378-751): 2.01e-120: 374: 30.02		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		992457 PPARA_HUMAN (337-751): 2.68e-120: 372: 27.80		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		500380 RARB_HUMAN (336-797): 9.97e-114: 354: 72.08		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		587211 RXRA_HUMAN (358-755): 8.24e-107: 337: 28.07		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		488042 RARA_HUMAN (350-797): 2.03e-106: 336: 90.40		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		782706 HNF4A_HUMAN (384-797): 7.78e-106: 335: 23.29		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		261424 PPARG_HUMAN (378-751): 2.01e-120: 374: 30.02		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		261481 PPARA_HUMAN (337-751): 2.68e-120: 372: 27.80		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		261399 RXRA_HUMAN (358-755): 8.24e-107: 337: 28.07		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		261381 RARA_HUMAN (350-797): 2.03e-106: 336: 90.40		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		261429 HNF4A_HUMAN (384-797): 7.78e-106: 335: 23.29		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		261390 RARG_HUMAN (384-778): 1.24e-105: 333: 77.98		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Mm
		986635 NR4A2_MOUSE (423-752): 6.77e-113: 357: 33.13		RCOR1_MOUSE (378-704): 1.76e-42: 166: 22.35
+	Hs
		782678 HNF4A_HUMAN (384-797): 7.78e-106: 335: 23.29		RCOR3_HUMAN (351-810): 1.25e-41: 163: 20.65
+	Mm
		509327 RARA_MOUSE (350-797): 9.54e-108: 339: 88.84		Q8BK32_MOUSE (1-280): 1.47e-40: 155: 49.66
+	Hs
		740556 PPARG_HUMAN (378-751): 2.01e-120: 374: 30.02		KMT2C_HUMAN (679-1264): 4.24e-16: 88: 11.93
+	Hs
		782640 HNF4A_HUMAN (384-797): 7.78e-106: 335: 23.29		MINT_HUMAN (80-1321): 6.8e-20: 100: 8.11
+	Hs
		782638 HNF4A_HUMAN (384-797): 7.78e-106: 335: 23.29		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		782595 HNF4A_HUMAN (384-797): 7.78e-106: 335: 23.29		KMT2C_HUMAN (679-1264): 4.24e-16: 88: 11.93
+	Hs
		782707 HNF4A_HUMAN (384-797): 7.78e-106: 335: 23.29		CABIN_HUMAN (722-1134): 2.25e-13: 78.9: 19.17