HitPredict

Interactor 1: RBBP5 (Q15291)
Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)
Gene: RBBP5

Interactor 2: BD1L1 (Q8NFC6)
Biorientation of chromosomes in cell division protein 1-like 1
Gene: BOD1L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	26496610, 31076518, 24981860, 33961781, 23508102
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0006974 - DNA damage response GO:0048188 - Set1C/COMPASS complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 538 Hs			1 3051
+	Hs
		903375 WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41		BD1L1_HUMAN (50-3051): 0: 2178: 100.00
+	Hs
		1070755 RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00		BOD1_HUMAN (40-186): 4.37e-77: 255: 61.22
+	Hs
		64595 RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00		MYH7B_HUMAN (20-983): 5.35e-31: 137: 8.30
+	Hs
		551715 RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00		DESP_HUMAN (205-1104): 1.48e-20: 102: 15.80
+	Hs
		792973 LIS1_HUMAN (104-423): 9.57e-53: 186: 9.65		CENPE_HUMAN (8-1229): 4.7e-35: 150: 7.96
+	Hs
		551766 WDR5B_HUMAN (2-225): 9.91e-62: 207: 16.88		DESP_HUMAN (205-1104): 1.48e-20: 102: 15.80
+	Hs
		551632 LIS1_HUMAN (104-423): 9.57e-53: 186: 9.65		DESP_HUMAN (205-1104): 1.48e-20: 102: 15.80
+	Hs
		724952 FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56		MYH9_HUMAN (569-1501): 3.76e-40: 167: 10.73
+	Hs
		728492 POC1A_HUMAN (145-538): 3.26e-45: 165: 10.89		MYH11_HUMAN (1128-1739): 1.32e-12: 76.6: 7.71
+	Hs
		551854 NLE1_HUMAN (2-135): 8.57e-34: 135: 18.38		DESP_HUMAN (205-1104): 1.48e-20: 102: 15.80
+	Hs
		1068625 FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56		PLEC_HUMAN (275-1676): 2.39e-27: 125: 9.38
+	Hs
		551723 SMU1_HUMAN (179-320): 3.28e-21: 99: 13.79		DESP_HUMAN (205-1104): 1.48e-20: 102: 15.80
+	Hs
		725215 FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56		MYH10_HUMAN (771-1629): 8.52e-24: 113: 11.04
+	Hs
		1067456 FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56		EEA1_HUMAN (16-765): 3.29e-23: 111: 7.19
+	Hs
		518903 PHIP_HUMAN (227-374): 6.69e-15: 80.4: 13.91		TPR_HUMAN (716-1751): 3.41e-22: 108: 9.42
+	Hs
		903240 WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41		PLEC_HUMAN (275-1676): 2.39e-27: 125: 9.38
+	Hs
		518846 WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41		TPR_HUMAN (716-1751): 3.41e-22: 108: 9.42
+	Hs
		551655 WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41		DESP_HUMAN (205-1104): 1.48e-20: 102: 15.80
+	Hs
		1268063 FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56		MY18A_HUMAN (545-1152): 4.98e-12: 74.5: 15.09
+	Hs
		903399 WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41		MY18A_HUMAN (545-1152): 4.98e-12: 74.5: 15.09