Protein: TYSY
Thymidylate synthase (TS) (TSase) (EC 2.1.1.45)

Gene: TYSY, TYMS
Organism: Homo sapiens
Interactions: 48
UniProt ID: P04818

Gene Ontology (top 5):
GO:0000900 - mRNA regulatory element binding translation repressor activity
GO:0004146 - dihydrofolate reductase activity
GO:0004799 - thymidylate synthase activity
GO:0005542 - folic acid binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

389575

LIMS1
LIM and senescent cell antigen-like-containing domain protein 1

3

0

High-throughput

0.638

High

389604

IPKG
cAMP-dependent protein kinase inhibitor gamma

2

0

High-throughput

0.602

High

389571

VCAM1
Vascular cell adhesion protein 1

2

0

High-throughput

0.576

High

245933

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.513

High

389567

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

389594

SNAG
Gamma-soluble NSF attachment protein

1

0

High-throughput

0.513

High

389603

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.513

High

389596

SH3G2
Endophilin-A1

1

0

High-throughput

0.486

High

389577

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.480

High

47738

RBM47
RNA-binding protein 47

1

1

High-throughput

0.479

High

348464

RASN
GTPase NRas

1

1

High-throughput

0.479

High

349791

RASK
GTPase KRas

1

1

High-throughput

0.479

High

389597

RENT2
Regulator of nonsense transcripts 2

1

0

High-throughput

0.460

High

226240

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

344917

CYTN
Cystatin-SN

1

0

Small-scale

0.458

High

359559

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

389568

PABP1
Polyadenylate-binding protein 1

1

0

High-throughput

0.458

High

389570

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

389572

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

389573

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

389578

H31
Histone H3.1

1

0

High-throughput

0.458

High

389579

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

389580

ILF3
Interleukin enhancer-binding factor 3

1

0

Small-scale

0.458

High

389582

FTM
Protein fantom

1

0

High-throughput

0.458

High

389583

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

389584

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.458

High

389585

DET1
DET1 homolog

1

0

High-throughput

0.458

High

389586

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

389590

POC5
Centrosomal protein POC5

1

0

High-throughput

0.458

High

389592

POC1B
POC1 centriolar protein homolog B

1

0

High-throughput

0.458

High

231845

MARH6
E3 ubiquitin-protein ligase MARCHF6

1

2

High-throughput

0.437

High

389587

MARH3
E3 ubiquitin-protein ligase MARCHF3

1

2

High-throughput

0.437

High

389602

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

2

High-throughput

0.437

High

389599

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

0

Small-scale

0.426

High

61513

ARG35
Rho guanine nucleotide exchange factor 35

1

0

High-throughput

0.279

Low

389581

RTN1
Reticulon-1

1

0

High-throughput

0.279

Low

389589

PRSR2
Proline and serine-rich protein 2

1

0

High-throughput

0.279

Low

389591

PSD4
PH and SEC7 domain-containing protein 4

1

0

High-throughput

0.279

Low

389598

TANC2
Protein TANC2

1

0

High-throughput

0.279

Low

389593

EFHD2
EF-hand domain-containing protein D2

1

0

High-throughput

0.269

Low

389566

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

389569

ITA4
Integrin alpha-4

1

0

High-throughput

0.249

Low

389574

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

389576

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

389588

MGDP1
Magnesium-dependent phosphatase 1

1

0

High-throughput

0.249

Low

389595

RNF5
E3 ubiquitin-protein ligase RNF5

1

0

High-throughput

0.249

Low

389600

BFAR
Bifunctional apoptosis regulator

1

0

High-throughput

0.249

Low

389601

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024