Protein: ALDR
Aldo-keto reductase 1B (EC 1.1.1.21) (EC 1.1.1.300) (EC 1.1.1.372) (EC 1.1.1.54) (Aldose reductase) (dAR1)

Gene: ALDR, Ar1
Organism: Drosophila melanogaster
Interactions: 237
UniProt ID: M9PF61

Gene Ontology (top 5):
GO:0004032 - aldose reductase (NADPH) activity
GO:0005615 - extracellular space
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

121223

Q7JVH6
LD24696p

1

16

High-throughput

0.575

High

121302

Q9VHX4
LD24679p

1

16

High-throughput

0.575

High

121339

Q9VTL0
FI19917p1

1

16

High-throughput

0.575

High

121341

Q9VTY2
Uncharacterized protein, isoform A

1

16

High-throughput

0.575

High

121378

Q9Y112
BcDNA.GH10614

1

16

High-throughput

0.575

High

121251

Q8T0F7
LD05823p

1

3

High-throughput

0.553

High

121306

Q9VJD4
LD24721p

2

6

High-throughput

0.513

High

47734

A0AQH0
Proteasome subunit beta

1

8

High-throughput

0.445

High

53943

A1Z892
1-Cys peroxiredoxin

1

11

High-throughput

0.445

High

95494

E2QCF1
ATP-citrate synthase

1

3

High-throughput

0.445

High

121154

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

4

High-throughput

0.445

High

121159

IPYR
Inorganic pyrophosphatase

1

4

High-throughput

0.445

High

121162

O97428
Ciboulot, isoform A

1

6

High-throughput

0.445

High

121164

HP1
Heterochromatin protein 1

1

2

High-throughput

0.445

High

121165

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

4

High-throughput

0.445

High

121166

ALF
Fructose-bisphosphate aldolase

1

4

High-throughput

0.445

High

121167

NDKA
Nucleoside diphosphate kinase

1

5

High-throughput

0.445

High

121168

PSA1
Proteasome subunit alpha type-1

1

8

High-throughput

0.445

High

121169

ENO
Enolase

1

4

High-throughput

0.445

High

121171

PSA4
Proteasome subunit alpha type-4

1

9

High-throughput

0.445

High

121173

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.445

High

121175

GLNA1
Glutamine synthetase 1, mitochondrial

1

3

High-throughput

0.445

High

121178

PSA71
Proteasome subunit alpha type-7-1

1

8

High-throughput

0.445

High

121180

PPIA
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.445

High

121183

CALR
Calreticulin

1

5

High-throughput

0.445

High

121184

TPIS
Triosephosphate isomerase

1

2

High-throughput

0.445

High

121185

VATB
V-type proton ATPase subunit B

1

7

High-throughput

0.445

High

121187

PSA2
Proteasome subunit alpha type-2

1

8

High-throughput

0.445

High

121188

PSB1
Proteasome subunit beta type-1

1

16

High-throughput

0.445

High

121190

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

1

5

High-throughput

0.445

High

121191

MOEH
Moesin/ezrin/radixin homolog 1

1

5

High-throughput

0.445

High

121192

FKB12
Peptidyl-prolyl cis-trans isomerase Fkbp12

1

19

High-throughput

0.445

High

121193

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

4

High-throughput

0.445

High

121196

DOD
Putative peptidyl-prolyl cis-trans isomerase dodo

1

5

High-throughput

0.445

High

121197

PDI
Protein disulfide-isomerase

1

14

High-throughput

0.445

High

121200

CALM
Calmodulin

1

2

High-throughput

0.445

High

121202

TRXR1
Thioredoxin reductase 1, mitochondrial

1

9

High-throughput

0.445

High

121203

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.445

High

121204

SODM
Superoxide dismutase [Mn], mitochondrial

1

3

High-throughput

0.445

High

121205

PGK
Phosphoglycerate kinase

1

4

High-throughput

0.445

High

121207

ATPB
ATP synthase subunit beta, mitochondrial

1

7

High-throughput

0.445

High

121208

GRAP
Growth factor receptor-bound protein 2

1

3

High-throughput

0.445

High

121209

Q0E8X8
ATP synthase F1 subunit epsilon

1

1

High-throughput

0.445

High

121210

Q0KHZ6
Electron transfer flavoprotein subunit beta

1

4

High-throughput

0.445

High

121212

ATP5H
ATP synthase subunit d, mitochondrial

1

1

High-throughput

0.445

High

121214

ATP5J
ATP synthase-coupling factor 6, mitochondrial

1

1

High-throughput

0.445

High

121217

NLP
Nucleoplasmin-like protein

1

9

High-throughput

0.445

High

121218

SAHH
Adenosylhomocysteinase

1

4

High-throughput

0.445

High

121219

NCPR
NADPH--cytochrome P450 reductase

1

2

High-throughput

0.445

High

121222

Q76NR6
Regucalcin

1

5

High-throughput

0.445

High

121226

Q7JX87
1-Cys peroxiredoxin

1

11

High-throughput

0.445

High

121227

Q7JXC4
CG6459 protein

1

4

High-throughput

0.445

High

121228

Q7K0E6
Aspartate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.445

High

121230

Q7K148
Proteasome subunit beta

1

8

High-throughput

0.445

High

121233

Q7K3Z3
GH01724p

1

2

High-throughput

0.445

High

121236

TERA
Transitional endoplasmic reticulum ATPase TER94

1

9

High-throughput

0.445

High

121237

Q7KN85
ATP-citrate synthase

1

3

High-throughput

0.445

High

121241

Q7KTW9
Asparagine synthetase [glutamine-hydrolyzing]

1

1

High-throughput

0.445

High

121242

QPCT2
Glutaminyl-peptide cyclotransferase

1

1

High-throughput

0.445

High

121243

Q8INK3
Fatty acid-binding protein, muscle

1

5

High-throughput

0.445

High

121244

Q8IQZ7
FI19014p1

1

6

High-throughput

0.445

High

121245

Q8IRD3
Glutathione peroxidase

1

5

High-throughput

0.445

High

121246

Q8MT58
Carnosine dipeptidase 2, isoform A

1

4

High-throughput

0.445

High

121255

ACPM
Acyl carrier protein, mitochondrial

1

4

High-throughput

0.445

High

121256

PSA5
Proteasome subunit alpha type-5

1

6

High-throughput

0.445

High

121259

JUPIT
Microtubule-associated protein Jupiter

1

4

High-throughput

0.445

High

121260

NASP
Nuclear autoantigenic sperm protein homolog

1

4

High-throughput

0.445

High

121262

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

4

High-throughput

0.445

High

121264

CP2B
Cardio acceleratory peptide 2b

1

2

High-throughput

0.445

High

121265

GCSH
Glycine cleavage system H protein, mitochondrial

1

1

High-throughput

0.445

High

121269

Q9V3V2
peptidylprolyl isomerase

1

19

High-throughput

0.445

High

121272

THIO2
Thioredoxin-2

1

9

High-throughput

0.445

High

121274

PSA3
Proteasome subunit alpha type-3

1

14

High-throughput

0.445

High

121275

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

2

High-throughput

0.445

High

121276

Q9V9U3
LD45254p

1

5

High-throughput

0.445

High

121278

Q9VAC1
GM14349p

1

4

High-throughput

0.445

High

121279

Q9VAC4
GEO09167p1

1

9

High-throughput

0.445

High

121281

Q9VAN7
Phosphoglycerate mutase

1

4

High-throughput

0.445

High

121282

Q9VAY2
Heat shock protein 83

1

11

High-throughput

0.445

High

121285

ORN
Probable oligoribonuclease

1

1

High-throughput

0.445

High

121286

Q9VCK6
LD34157p

1

4

High-throughput

0.445

High

121287

Q9VD02
GH14779p

1

9

High-throughput

0.445

High

121288

Q9VD29
small monomeric GTPase

1

5

High-throughput

0.445

High

121289

Q9VEB1
Malate dehydrogenase, mitochondrial

1

5

High-throughput

0.445

High

121291

FLNA
Filamin-A

1

6

High-throughput

0.445

High

121293

Q9VFF0
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.445

High

121294

Q9VG31
Malic enzyme

1

5

High-throughput

0.445

High

121298

Q9VH81
protein-serine/threonine phosphatase

1

2

High-throughput

0.445

High

121299

TEBPH
Cytosolic Prostaglandin E synthase

1

5

High-throughput

0.445

High

121300

Q9VHN7
transketolase

1

4

High-throughput

0.445

High

121301

DPP3
Dipeptidyl peptidase 3

1

3

High-throughput

0.445

High

121304

Q9VIE8
Aconitate hydratase, mitochondrial

1

4

High-throughput

0.445

High

121305

Q9VII9
Glyoxylate reductase/hydroxypyruvate reductase

1

3

High-throughput

0.445

High

121307

Q9VJJ0
Proteasome subunit beta

1

13

High-throughput

0.445

High

121308

Q9VJZ6
LD40224p

1

11

High-throughput

0.445

High

121309

Q9VK60
GH25425p

1

9

High-throughput

0.445

High

121310

Q9VKB0
threonine--tRNA ligase

1

4

High-throughput

0.445

High

121311

Q9VKW5
Prolyl endopeptidase

1

4

High-throughput

0.445

High

121312

Q9VKZ8
Ubiquitin carboxyl-terminal hydrolase

1

1

High-throughput

0.445

High

121313

EF1D
Probable elongation factor 1-delta

1

4

High-throughput

0.445

High

121314

Q9VL68
Enoyl-CoA delta isomerase 1, mitochondrial

1

5

High-throughput

0.445

High

121315

Q9VL70
HL08109p

1

4

High-throughput

0.445

High

121317

Q9VLB7
Rab GDP dissociation inhibitor

1

5

High-throughput

0.445

High

121318

AK200
A-kinase anchor protein 200

1

5

High-throughput

0.445

High

121319

SYAC
Alanine--tRNA ligase, cytoplasmic

1

7

High-throughput

0.445

High

121321

GUAD
Guanine deaminase

1

1

High-throughput

0.445

High

121322

PSB4
Proteasome subunit beta type-4

1

20

High-throughput

0.445

High

121327

Q9VQ61
Aspartate aminotransferase

1

6

High-throughput

0.445

High

121328

BACC
Bacchus

1

4

High-throughput

0.445

High

121329

Q9VQL1
serine--tRNA ligase

1

8

High-throughput

0.445

High

121330

Q9VRD4
Uncharacterized protein, isoform A

1

4

High-throughput

0.445

High

121332

Q9VRL1
GEO06356p1

1

5

High-throughput

0.445

High

121335

Q9VSI6
Isocitrate dehydrogenase [NADP]

1

4

High-throughput

0.445

High

121337

Q9VST4
arginine kinase

1

1

High-throughput

0.445

High

121342

Q9VU35
10 kDa heat shock protein, mitochondrial

1

4

High-throughput

0.445

High

121344

Q9VUC1
Hsc70Cb, isoform A

1

8

High-throughput

0.445

High

121349

Q9VW59
Rho GDP-dissociation inhibitor 3

1

4

High-throughput

0.445

High

121350

Q9VW70
FI21813p1

1

2

High-throughput

0.445

High

121353

Q9VXQ3
Diphosphomevalonate decarboxylase

1

2

High-throughput

0.445

High

121354

CLIC
Chloride intracellular channel Clic

1

9

High-throughput

0.445

High

121360

Q9W022
GEO01508p1

1

14

High-throughput

0.445

High

121363

SND1
Staphylococcal nuclease domain-containing protein 1

1

4

High-throughput

0.445

High

121365

Q9W227
Peptidyl-prolyl cis-trans isomerase

1

7

High-throughput

0.445

High

121367

Q9W3X6
fumarate hydratase

1

5

High-throughput

0.445

High

121369

CISY
Probable citrate synthase, mitochondrial

1

7

High-throughput

0.445

High

121370

WUHO
tRNA

1

6

High-throughput

0.445

High

121371

Q9W457
Serine hydroxymethyltransferase

1

4

High-throughput

0.445

High

121372

Q9W478
RE43153p

1

5

High-throughput

0.445

High

121373

PSB3
Proteasome subunit beta type-3

1

16

High-throughput

0.445

High

121376

PSA6
Proteasome subunit alpha type-6

1

16

High-throughput

0.445

High

121211

DYL1
Dynein light chain 1, cytoplasmic

1

0

High-throughput

0.438

High

121277

Q9VA42
Niemann-Pick type C-2g, isoform A

1

1

High-throughput

0.437

High

121174

JANA
Sex-regulated protein janus-A

1

0

High-throughput

0.426

High

121182

YEMA
yemanuclein

1

0

High-throughput

0.426

High

121194

GRPE
GrpE protein homolog, mitochondrial

1

0

High-throughput

0.426

High

121215

ATPO
ATP synthase subunit O, mitochondrial

1

0

High-throughput

0.426

High

121229

Q7K0W1
LD27406p

1

0

High-throughput

0.426

High

121238

Q7KN94
Electron transfer flavoprotein subunit alpha

1

0

High-throughput

0.426

High

121221

Q5U0Y0
Paired amphipathic helix protein Sin3a

1

1

High-throughput

0.417

High

53825

A1Z864
FI01421p

1

1

High-throughput

0.407

High

57489

A1ZB71
Glutathione S transferase E6

1

11

High-throughput

0.407

High

57720

A1ZB77
Uncharacterized protein, isoform J

1

4

High-throughput

0.407

High

86434

B9EQV3
Endoplasmic reticulum transmembrane protein

1

4

High-throughput

0.407

High

121151

UGDH
UDP-glucose 6-dehydrogenase

1

1

High-throughput

0.407

High

121152

O16043
Anon1A4

1

4

High-throughput

0.407

High

121153

O18335
Rab11

1

1

High-throughput

0.407

High

121155

VINC
Vinculin

1

4

High-throughput

0.407

High

121156

LOK
Ovarian-specific serine/threonine-protein kinase Lok

1

1

High-throughput

0.407

High

121157

RS21
Small ribosomal subunit protein eS21

1

5

High-throughput

0.407

High

121158

TRMB
tRNA

1

4

High-throughput

0.407

High

121160

O97102
Small ubiquitin-related modifier

1

5

High-throughput

0.407

High

121161

O97121
cystathionine gamma-lyase

1

4

High-throughput

0.407

High

121163

INO1
Inositol-3-phosphate synthase

1

5

High-throughput

0.407

High

121170

PCNA
Proliferating cell nuclear antigen

1

4

High-throughput

0.407

High

121172

SYB
Synaptobrevin

1

1

High-throughput

0.407

High

121176

ANXB9
Annexin B9

1

9

High-throughput

0.407

High

121177

ANX10
Annexin B10

1

9

High-throughput

0.407

High

121181

PROF
Profilin

1

4

High-throughput

0.407

High

121186

UCHL
Ubiquitin carboxyl-terminal hydrolase

1

7

High-throughput

0.407

High

121195

SET
Protein SET

1

2

High-throughput

0.407

High

121198

VATE
V-type proton ATPase subunit E

1

4

High-throughput

0.407

High

121199

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.407

High

121201

CYC2
Cytochrome c-2

1

2

High-throughput

0.407

High

121206

HMGD
High mobility group protein D

1

3

High-throughput

0.407

High

121213

SEM1A
Semaphorin-1A

1

1

High-throughput

0.407

High

121216

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

10

High-throughput

0.407

High

121220

Q3YMU0
Protein disulfide-isomerase

1

9

High-throughput

0.407

High

121225

Q7JVZ8
Glutathione S transferase E11, isoform A

1

11

High-throughput

0.407

High

121231

Q7K2K2
FI04612p

1

4

High-throughput

0.407

High

121232

Q7K3J0
T-complex protein 1 subunit theta

1

3

High-throughput

0.407

High

121234

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

1

High-throughput

0.407

High

121235

Q7KKI0
T-complex protein 1 subunit epsilon

1

2

High-throughput

0.407

High

121239

Q7KN99
Phosphopantothenoylcysteine synthetase, isoform A

1

4

High-throughput

0.407

High

121240

Q7KTW5
Inositol-1-monophosphatase

1

4

High-throughput

0.407

High

121247

Q8MYY7
RE44624p

1

4

High-throughput

0.407

High

121248

Q8STA5
Histidine triad nucleotide binding protein 1, isoform A

1

4

High-throughput

0.407

High

121249

OLA1
Obg-like ATPase 1

1

5

High-throughput

0.407

High

121250

Q8SYG3
E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.407

High

121252

Q8T0L3
E1 ubiquitin-activating enzyme

1

4

High-throughput

0.407

High

121254

NACA
Nascent polypeptide-associated complex subunit alpha

1

4

High-throughput

0.407

High

121257

FAXC
Failed axon connections

1

4

High-throughput

0.407

High

121258

IF5A
Eukaryotic translation initiation factor 5A

1

5

High-throughput

0.407

High

121261

Q9I7K7
Arrestin C-terminal-like domain-containing protein

1

1

High-throughput

0.407

High

121263

SH3BG
SH3 domain-binding glutamic acid-rich protein homolog

1

5

High-throughput

0.407

High

121267

Q9V3D8
GH27579p

1

1

High-throughput

0.407

High

121268

Q9V3I1
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

4

High-throughput

0.407

High

121270

SPC25
Kinetochore protein Spc25

1

2

High-throughput

0.407

High

121271

Q9V3V9
Endonuclease G inhibitor, isoform A

1

4

High-throughput

0.407

High

121273

PDIA6
Protein disulfide-isomerase A6 homolog

1

11

High-throughput

0.407

High

121280

Q9VAG3
trypsin

1

1

High-throughput

0.407

High

121283

Q9VBR6
RE74917p

1

4

High-throughput

0.407

High

121284

Q9VBT1
CHK kinase-like domain-containing protein

1

2

High-throughput

0.407

High

121290

Q9VEH3
Uncharacterized protein, isoform A

1

1

High-throughput

0.407

High

121295

Q9VG33
Sulfurtransferase

1

4

High-throughput

0.407

High

121296

Q9VGK3
peptidylprolyl isomerase

1

19

High-throughput

0.407

High

121297

TCTP
Translationally-controlled tumor protein homolog

1

4

High-throughput

0.407

High

121303

Q9VIC3
carboxylesterase

1

1

High-throughput

0.407

High

121316

FKB59
FK506-binding protein 59

1

14

High-throughput

0.407

High

121320

Q9VMU6
LD31822p

1

4

High-throughput

0.407

High

121323

Q9VNB2
RE42193p

1

4

High-throughput

0.407

High

121324

Q9VP52
GH24315p

1

2

High-throughput

0.407

High

121325

Q9VPN5
Stress-induced-phosphoprotein 1

1

6

High-throughput

0.407

High

121326

Q9VPX6
Adenylyl cyclase-associated protein

1

4

High-throughput

0.407

High

121331

Q9VRD6
NTF2-related export protein

1

4

High-throughput

0.407

High

121333

Q9VRP2
Uncharacterized protein, isoform A

1

7

High-throughput

0.407

High

121334

Q9VS98
LD12639p

1

1

High-throughput

0.407

High

121336

Q9VSL2
Glutathione S transferase O3

1

9

High-throughput

0.407

High

121340

Q9VTX2
RE32936p

1

1

High-throughput

0.407

High

121343

WDR1
Actin-interacting protein 1

1

5

High-throughput

0.407

High

121345

Y9705
Cold shock domain-containing protein CG9705

1

4

High-throughput

0.407

High

121346

CHMP5
Charged multivesicular body protein 5

1

2

High-throughput

0.407

High

121347

Q9VVL7
Dihydrolipoyl dehydrogenase

1

9

High-throughput

0.407

High

121351

RS10B
Small ribosomal subunit protein eS10B

1

5

High-throughput

0.407

High

121352

DHB4
Peroxisomal multifunctional enzyme type 2

1

4

High-throughput

0.407

High

121355

Q9VYB9
LP02557p

1

1

High-throughput

0.407

High

121357

TXND5
Thioredoxin domain-containing protein 5 homolog

1

16

High-throughput

0.407

High

121358

Q9VZI1
Transgelin

1

5

High-throughput

0.407

High

121359

Q9VZY0
LD45195p

1

1

High-throughput

0.407

High

121361

OSM1
Intraflagellar transport protein 172 homolog

1

1

High-throughput

0.407

High

121362

Q9W0H8
Reticulocalbin-3

1

7

High-throughput

0.407

High

121366

Q9W2M4
Farnesoic acid O-methyl transferase domain-containing protein

1

3

High-throughput

0.407

High

121368

Q9W3Y3
Calcyclin-binding protein

1

4

High-throughput

0.407

High

121374

Q9XYZ9
Glutathione S transferase E12, isoform A

1

11

High-throughput

0.407

High

121375

Q9XZ57
Eb1, isoform E

1

4

High-throughput

0.407

High

121377

PURA
Adenylosuccinate synthetase

1

4

High-throughput

0.407

High

121266

Q9U9Q2
Neosin, isoform A

1

0

High-throughput

0.238

Low

121338

Q9VT01
FI06792p

1

0

High-throughput

0.238

Low

121348

Q9VVU4
CBF1-interacting co-repressor CIR N-terminal domain-containing protein

1

0

High-throughput

0.238

Low

121364

Q9W1T1
Large ribosomal subunit protein eL22

1

0

High-throughput

0.238

Low

54396

C19L1
CWF19-like protein 1 homolog

1

0

High-throughput

0.232

Low

54412

A1Z8J5
Shavenoid, isoform A

1

0

High-throughput

0.232

Low

121179

GNAQ
G protein alpha q subunit

1

0

High-throughput

0.232

Low

121189

PEP
Zinc finger protein on ecdysone puffs

1

0

High-throughput

0.232

Low

121224

Q7JVY2
Double parked, isoform A

1

0

High-throughput

0.232

Low

121253

Q8T0U6
Serine/threonine-protein phosphatase

1

0

High-throughput

0.232

Low

121292

Q9VFA8
Uncharacterized protein, isoform D

1

0

High-throughput

0.232

Low

121356

Q9VYP5
Uncharacterized protein, isoform B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025