HitPredict

Interactor 1: NCOA2 (Q15596)
Nuclear receptor coactivator 2 (NCoA-2) (Class E basic helix-loop-helix protein 75) (bHLHe75) (Transcriptional intermediary factor 2) (hTIF2)
Gene: NCOA2

Interactor 2: KLF15 (Q9UIH9)
Krueppel-like factor 15 (Kidney-enriched krueppel-like factor)
Gene: KLF15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35140242, 35016035
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1464 Hs			1 416
+	Hs
		1046689 NCOA2_HUMAN (1-1464): 0: 616: 100.00		KLF5_HUMAN (312-404): 4.14e-34: 134: 64.52
+	Hs
		316893 NCOA2_HUMAN (1-1464): 0: 616: 100.00		KLF8_HUMAN (319-403): 5.41e-31: 123: 63.53
+	Hs
		435109 HIF1A_HUMAN (13-835): 8.2e-109: 366: 13.75		SP1_HUMAN (319-404): 4.98e-29: 121: 63.95
+	Hs
		1046781 NCOA3_HUMAN (1-1413): 4.69e-96: 342: 38.52		KLF5_HUMAN (312-404): 4.14e-34: 134: 64.52
+	Hs
		317049 NCOA3_HUMAN (1-1413): 4.69e-96: 342: 38.52		KLF8_HUMAN (319-403): 5.41e-31: 123: 63.53
+	Hs
		435165 EPAS1_HUMAN (13-798): 4.66e-96: 332: 14.47		SP1_HUMAN (319-404): 4.98e-29: 121: 63.95
+	Hs
		1355818 NCOA3_HUMAN (1-1413): 4.69e-96: 342: 38.52		KLF15_HUMAN (349-414): 7.07e-21: 95.9: 36.77
+	Hs
		434982 AHR_HUMAN (4-769): 3.6e-77: 276: 12.82		SP1_HUMAN (319-404): 4.98e-29: 121: 63.95
+	Hs
		434958 ARNT_HUMAN (4-664): 7.44e-75: 268: 14.99		SP1_HUMAN (319-404): 4.98e-29: 121: 63.95
+	Hs
		1078547 NCOA1_HUMAN (1-1460): 8.21e-80: 292: 28.32		KLF15_HUMAN (349-414): 7.07e-21: 95.9: 36.77
+	Hs
		1046715 KMT2C_HUMAN (670-1422): 5e-11: 70.1: 13.05		KLF5_HUMAN (312-404): 4.14e-34: 134: 64.52
+	Hs
		1243850 KMT2C_HUMAN (670-1422): 5e-11: 70.1: 13.05		KLF15_HUMAN (349-414): 7.07e-21: 95.9: 36.77