HitPredict

Interactor 1: G5EFX2 (G5EFX2)
protein kinase C (EC 2.7.11.13)
Gene: pkn-1

Interactor 2: RHO1 (Q22038)
Ras-like GTP-binding protein rhoA
Gene: rho-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	21277858
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HR1~Ras, Pkinase~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1012 Ce			1 192
+	Ce
		107919 G5EFX2_CAEEL (1-1012): 0: 1148: 100.00		RAC1_CAEEL (1-192): 1.02e-80: 239: 55.96
+	Ce
		104463 G5EFX2_CAEEL (1-1012): 0: 1148: 100.00		G5EBV3_CAEEL (2-192): 9.05e-78: 232: 52.08
+	Hs
		925308 PKN2_HUMAN (49-1010): 0: 1061: 35.88		RAC1_HUMAN (1-192): 5.49e-81: 240: 58.76
+	Hs
		900514 PKN2_HUMAN (49-1010): 0: 1061: 35.88		RHOA_HUMAN (1-192): 2.88e-79: 236: 87.57
+	Hs
		951021 PKN2_HUMAN (49-1010): 0: 1061: 35.88		RHOG_HUMAN (1-192): 2.68e-78: 233: 55.73
+	Hs
		545401 PKN2_HUMAN (49-1010): 0: 1061: 35.88		RAC2_HUMAN (1-192): 1.63e-77: 231: 55.67
+	Hs
		436326 PKN2_HUMAN (49-1010): 0: 1061: 35.88		RHOC_HUMAN (1-192): 3.71e-77: 230: 84.46
+	Hs
		894056 PKN2_HUMAN (49-1010): 0: 1061: 35.88		CDC42_HUMAN (1-192): 4.64e-76: 228: 52.85
+	Hs
		915706 PKN2_HUMAN (49-1010): 0: 1061: 35.88		RHOB_HUMAN (1-190): 2.32e-75: 226: 80.53
+	Hs
		925307 PKN1_HUMAN (83-1010): 0: 945: 35.43		RAC1_HUMAN (1-192): 5.49e-81: 240: 58.76
+	Hs
		900513 PKN1_HUMAN (83-1010): 0: 945: 35.43		RHOA_HUMAN (1-192): 2.88e-79: 236: 87.57
+	Hs
		915705 PKN1_HUMAN (83-1010): 0: 945: 35.43		RHOB_HUMAN (1-190): 2.32e-75: 226: 80.53
+	Hs
		900594 PKN3_HUMAN (64-1010): 0: 904: 33.85		RHOA_HUMAN (1-192): 2.88e-79: 236: 87.57
+	Hs
		915766 PKN3_HUMAN (64-1010): 0: 904: 33.85		RHOB_HUMAN (1-190): 2.32e-75: 226: 80.53
+	Sp
		736865 PCK2_SCHPO (598-1010): 3.37e-147: 466: 41.63		RHO5_SCHPO (4-192): 7.94e-94: 273: 64.29
+	Sp
		736859 PCK2_SCHPO (598-1010): 3.37e-147: 466: 41.63		RHO1_SCHPO (1-192): 9.31e-83: 245: 66.34
+	Hs
		681775 AKT1_HUMAN (568-1010): 1.89e-155: 470: 34.38		RAC1_HUMAN (1-192): 5.49e-81: 240: 58.76
+	Sp
		736857 PCK2_SCHPO (598-1010): 3.37e-147: 466: 41.63		CDC42_SCHPO (1-192): 1.94e-77: 231: 53.61
+	Sp
		736860 PCK2_SCHPO (598-1010): 3.37e-147: 466: 41.63		RHO2_SCHPO (4-192): 3.87e-77: 231: 58.03
+	Sp
		736864 PCK2_SCHPO (598-1010): 3.37e-147: 466: 41.63		RHO4_SCHPO (6-174): 6.2e-71: 215: 60.23