HitPredict

Interactor 1: USF2 (Q15853)
Upstream stimulatory factor 2 (Class B basic helix-loop-helix protein 12) (bHLHb12) (FOS-interacting protein) (FIP) (Major late transcription factor 2) (Upstream transcription factor 2)
Gene: USF2

Interactor 2: USF2 (Q15853)
Upstream stimulatory factor 2 (Class B basic helix-loop-helix protein 12) (bHLHb12) (FOS-interacting protein) (FIP) (Major late transcription factor 2) (Upstream transcription factor 2)
Gene: USF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.819

The method score is based on:

Property Details
Experiments 17353931, 8576131
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH
Common GO terms GO:0000430 - regulation of transcription from RNA polymerase II promoter by glucose
GO:0000432 - positive regulation of transcription from RNA polymerase II promoter by glucose
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
and 14 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 346
Hs

1 346
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Last updated: 15 Jul 2024