Protein: ERAL1
GTPase Era, mitochondrial (H-ERA) (hERA) (Conserved ERA-like GTPase) (CEGA) (ERA-W) (ERA-like protein 1)

Gene: ERAL1
Organism: Homo sapiens
Interactions: 205
UniProt ID: O75616

Gene Ontology (top 5):
GO:0000028 - ribosomal small subunit assembly
GO:0003723 - RNA binding
GO:0005525 - GTP binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

288959

ATPF1
ATP synthase mitochondrial F1 complex assembly factor 1

3

1

High-throughput

0.667

High

171967

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

3

6

High-throughput

0.662

High

288979

NOA1
Nitric oxide-associated protein 1

1

0

High-throughput

0.656

High

289009

RT26
Small ribosomal subunit protein mS26

3

2

Small-scale

0.650

High

288880

AIFM1
Apoptosis-inducing factor 1, mitochondrial

3

5

High-throughput

0.643

High

288908

IF2M
Translation initiation factor IF-2, mitochondrial

1

11

High-throughput

0.618

High

288910

EFTU
Elongation factor Tu, mitochondrial

1

6

High-throughput

0.618

High

288985

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

8

High-throughput

0.618

High

289003

EFGM
Elongation factor G, mitochondrial

1

9

High-throughput

0.618

High

289022

MTG2
Mitochondrial ribosome-associated GTPase 2

1

6

High-throughput

0.618

High

289056

RM11
Large ribosomal subunit protein uL11m

1

3

High-throughput

0.618

High

288944

CUL3
Cullin-3

2

5

High-throughput

0.611

High

288946

ICT1
Large ribosomal subunit protein mL62

2

3

High-throughput

0.611

High

288974

FABD
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial

2

1

High-throughput

0.611

High

288994

MTEF3
Transcription termination factor 3, mitochondrial

2

2

High-throughput

0.611

High

289055

RT02
Small ribosomal subunit protein uS2m

2

9

High-throughput

0.611

High

288884

CO1A1
Collagen alpha-1(I) chain

3

2

High-throughput

0.609

High

288885

CO3A1

3

2

High-throughput

0.609

High

288888

CO1A2
Collagen alpha-2(I) chain

3

2

High-throughput

0.609

High

288981

RT27
Small ribosomal subunit protein mS27

2

1

High-throughput

0.601

High

289041

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

2

1

High-throughput

0.601

High

289058

RT18C
Small ribosomal subunit protein bS18m

2

2

High-throughput

0.601

High

279592

CISY
Citrate synthase, mitochondrial

2

5

High-throughput

0.584

High

288934

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

2

2

Small-scale

0.584

High

288939

GRSF1
G-rich sequence factor 1

2

11

High-throughput

0.584

High

288956

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

3

High-throughput

0.584

High

289046

ZRAN1
Ubiquitin thioesterase ZRANB1

2

6

High-throughput

0.584

High

288931

TFAM
Transcription factor A, mitochondrial

2

5

High-throughput

0.571

High

288932

SSBP
Single-stranded DNA-binding protein, mitochondrial

2

2

High-throughput

0.571

High

288947

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

2

5

Small-scale

0.571

High

288976

ZC3H3
Zinc finger CCCH domain-containing protein 3

2

1

High-throughput

0.558

High

289004

IMP2L
Mitochondrial inner membrane protease subunit 2

1

3

High-throughput

0.554

High

289050

ADIP
Afadin- and alpha-actinin-binding protein

2

1

High-throughput

0.553

High

289010

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.549

High

134210

RPOM
DNA-directed RNA polymerase, mitochondrial

1

1

High-throughput

0.536

High

288911

RT29
Small ribosomal subunit protein mS29

1

1

High-throughput

0.536

High

288919

RT22
Small ribosomal subunit protein mS22

1

1

High-throughput

0.536

High

288920

RT25
Small ribosomal subunit protein mS25

1

1

High-throughput

0.536

High

288921

RT10
Small ribosomal subunit protein uS10m

1

5

High-throughput

0.536

High

288922

RT35
Small ribosomal subunit protein mS35

1

1

High-throughput

0.536

High

288923

RT05
Small ribosomal subunit protein uS5m

1

5

High-throughput

0.536

High

288924

RT11
Small ribosomal subunit protein uS11m

1

3

High-throughput

0.536

High

288926

RT34
Small ribosomal subunit protein mS34

1

1

High-throughput

0.536

High

288927

RT06
Small ribosomal subunit protein bS6m

1

1

High-throughput

0.536

High

288928

RT09
Small ribosomal subunit protein uS9m

1

4

High-throughput

0.536

High

288936

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

1

High-throughput

0.536

High

288951

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

4

High-throughput

0.536

High

288953

SRSF7
Serine/arginine-rich splicing factor 7

1

5

High-throughput

0.536

High

288965

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

1

2

High-throughput

0.536

High

288972

THOC4
THO complex subunit 4

1

5

High-throughput

0.536

High

288973

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

5

High-throughput

0.536

High

288996

RT24
Small ribosomal subunit protein uS3m

1

1

High-throughput

0.536

High

288998

PTCD3
Small ribosomal subunit protein mS39

1

1

High-throughput

0.536

High

288999

NEIL1
Endonuclease 8-like 1

1

2

High-throughput

0.536

High

289002

IMP1L
Mitochondrial inner membrane protease subunit 1

1

3

High-throughput

0.536

High

289005

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.536

High

289027

LN28A
Protein lin-28 homolog A

1

5

High-throughput

0.536

High

289047

ABT1
Activator of basal transcription 1

1

2

High-throughput

0.536

High

289052

RT17
Small ribosomal subunit protein uS17m

1

1

High-throughput

0.536

High

289053

RT07
Small ribosomal subunit protein uS7m

1

3

High-throughput

0.536

High

289054

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

3

High-throughput

0.536

High

289057

RT16
Small ribosomal subunit protein bS16m

1

1

High-throughput

0.536

High

289059

RT23
Small ribosomal subunit protein mS23

1

1

High-throughput

0.536

High

289062

RT18B
Small ribosomal subunit protein mS40

1

1

High-throughput

0.536

High

288883

MYC
Myc proto-oncogene protein

2

7

High-throughput

0.533

High

160668

TOR1A
Torsin-1A

1

2

High-throughput

0.515

High

177498

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

0

High-throughput

0.513

High

219896

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.513

High

288918

PRR3
Proline-rich protein 3

1

0

High-throughput

0.513

High

288925

RT15
Small ribosomal subunit protein uS15m

1

0

High-throughput

0.513

High

288977

SUV3
ATP-dependent RNA helicase SUPV3L1, mitochondrial

1

0

High-throughput

0.513

High

289014

5NT3A
Cytosolic 5'-nucleotidase 3A

1

0

High-throughput

0.513

High

289044

ANFY1
Rabankyrin-5

1

0

High-throughput

0.513

High

288954

SMN
Survival motor neuron protein

1

0

High-throughput

0.493

High

221903

FOXS1
Forkhead box protein S1

1

1

High-throughput

0.489

High

288913

FOXA3
Hepatocyte nuclear factor 3-gamma

1

1

High-throughput

0.489

High

288949

P2RY6
P2Y purinoceptor 6

1

1

High-throughput

0.489

High

288966

ZN574
Zinc finger protein 574

1

1

High-throughput

0.489

High

289031

ANM8
Protein arginine N-methyltransferase 8

1

3

High-throughput

0.489

High

289051

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

2

High-throughput

0.489

High

288937

SRSF4
Serine/arginine-rich splicing factor 4

1

7

High-throughput

0.481

High

288988

EXOS8
Exosome complex component RRP43

1

4

High-throughput

0.481

High

289026

ECT2
Protein ECT2

1

2

High-throughput

0.481

High

61378

VWA8
von Willebrand factor A domain-containing protein 8

1

2

High-throughput

0.479

High

66103

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

2

High-throughput

0.479

High

183557

RT12
Small ribosomal subunit protein uS12m

1

2

High-throughput

0.479

High

240297

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

281838

MPPB
Mitochondrial-processing peptidase subunit beta

1

5

High-throughput

0.479

High

287211

RF1M
Peptide chain release factor 1, mitochondrial

1

7

High-throughput

0.479

High

288881

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

2

High-throughput

0.479

High

288886

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

6

High-throughput

0.479

High

288889

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

4

High-throughput

0.479

High

288890

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

6

High-throughput

0.479

High

288892

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

2

High-throughput

0.479

High

288893

CH60
60 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.479

High

288894

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

1

High-throughput

0.479

High

288897

RL10
Large ribosomal subunit protein uL16

1

4

High-throughput

0.479

High

288898

STIP1
Stress-induced-phosphoprotein 1

1

5

High-throughput

0.479

High

288899

PHB1
Prohibitin 1

1

3

High-throughput

0.479

High

288900

FUS
RNA-binding protein FUS

1

5

High-throughput

0.479

High

288901

TGFR2
TGF-beta receptor type-2

1

1

High-throughput

0.479

High

288902

HSPA9
Stress-70 protein, mitochondrial

1

5

High-throughput

0.479

High

288903

MDHM
Malate dehydrogenase, mitochondrial

1

6

High-throughput

0.479

High

288904

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

288905

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

3

High-throughput

0.479

High

288907

EFTS
Elongation factor Ts, mitochondrial

1

3

High-throughput

0.479

High

288909

SOX2
Transcription factor SOX-2

1

6

High-throughput

0.479

High

288912

PLK1
Serine/threonine-protein kinase PLK1

1

3

High-throughput

0.479

High

288917

RHOA
Transforming protein RhoA

1

5

High-throughput

0.479

High

288930

RHOG
Rho-related GTP-binding protein RhoG

1

4

High-throughput

0.479

High

288933

FAK1
Focal adhesion kinase 1

1

11

High-throughput

0.479

High

288938

MPPA
Mitochondrial-processing peptidase subunit alpha

1

5

High-throughput

0.479

High

288940

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

4

High-throughput

0.479

High

288941

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

1

High-throughput

0.479

High

288942

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

288943

SQSTM
Sequestosome-1

1

2

High-throughput

0.479

High

288945

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

6

High-throughput

0.479

High

288948

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

288950

PDK1
[Pyruvate dehydrogenase

1

3

High-throughput

0.479

High

288952

RHOH
Rho-related GTP-binding protein RhoH

1

6

High-throughput

0.479

High

288957

CL16A
Protein CLEC16A

1

2

High-throughput

0.479

High

288958

SYAM
Alanine--tRNA ligase, mitochondrial

1

3

High-throughput

0.479

High

288961

MRM1
rRNA methyltransferase 1, mitochondrial

1

3

High-throughput

0.479

High

288963

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

2

High-throughput

0.479

High

288968

DHX30
ATP-dependent RNA helicase DHX30

1

5

High-throughput

0.479

High

288969

MEPCE
7SK snRNA methylphosphate capping enzyme

1

2

High-throughput

0.479

High

288970

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

5

High-throughput

0.479

High

288975

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.479

High

288978

PLD6
Mitochondrial cardiolipin hydrolase

1

1

High-throughput

0.479

High

288982

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

288983

FBXW7
F-box/WD repeat-containing protein 7

1

6

High-throughput

0.479

High

288984

FBX32
F-box only protein 32

1

2

High-throughput

0.479

High

288986

FAKD4
FAST kinase domain-containing protein 4

1

5

High-throughput

0.479

High

288987

MCUR1
Mitochondrial calcium uniporter regulator 1

1

2

High-throughput

0.479

High

288989

CHCH1
Small ribosomal subunit protein mS37

1

2

High-throughput

0.479

High

288990

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

2

High-throughput

0.479

High

288991

COQ8B
Atypical kinase COQ8B, mitochondrial

1

1

High-throughput

0.479

High

288993

RRFM
Ribosome-recycling factor, mitochondrial

1

2

High-throughput

0.479

High

288997

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

1

High-throughput

0.479

High

289001

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.479

High

289006

TACO1
Translational activator of cytochrome c oxidase 1

1

2

High-throughput

0.479

High

289007

TR61B
tRNA

1

1

High-throughput

0.479

High

289008

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

5

High-throughput

0.479

High

289011

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

6

High-throughput

0.479

High

289012

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

2

High-throughput

0.479

High

289015

CCDC8
Coiled-coil domain-containing protein 8

1

4

High-throughput

0.479

High

289016

IF3M
Translation initiation factor IF-3, mitochondrial

1

1

High-throughput

0.479

High

289019

MTRFR
Mitochondrial translation release factor in rescue

1

8

High-throughput

0.479

High

289021

RHOJ
Rho-related GTP-binding protein RhoJ

1

7

High-throughput

0.479

High

289024

MET17
Ribosome assembly protein METTL17, mitochondrial

1

2

High-throughput

0.479

High

289025

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

10

High-throughput

0.479

High

289028

ZFYV1
Zinc finger FYVE domain-containing protein 1

1

2

Small-scale

0.479

High

289029

BRD7
Bromodomain-containing protein 7

1

7

High-throughput

0.479

High

289030

ANLN
Anillin

1

2

High-throughput

0.479

High

289033

DDX28
Probable ATP-dependent RNA helicase DDX28

1

3

High-throughput

0.479

High

289034

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

3

High-throughput

0.479

High

289038

AKIP
Small ribosomal subunit protein mS38

1

1

High-throughput

0.479

High

289040

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

5

High-throughput

0.479

High

289043

MRES1
Mitochondrial transcription rescue factor 1

1

2

High-throughput

0.479

High

289045

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

8

High-throughput

0.479

High

289048

FZR1
Fizzy-related protein homolog

1

10

High-throughput

0.479

High

137585

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

274950

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

288879

DUS14
Dual specificity protein phosphatase 14

1

0

High-throughput

0.458

High

288891

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

288955

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

High-throughput

0.458

High

288964

CH082
UPF0598 protein C8orf82

1

0

High-throughput

0.458

High

288980

MAIP1
m-AAA protease-interacting protein 1, mitochondrial

1

0

High-throughput

0.458

High

288992

FMT
Methionyl-tRNA formyltransferase, mitochondrial

1

0

High-throughput

0.458

High

288995

SPDLY
Protein Spindly

1

0

High-throughput

0.458

High

289000

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.458

High

289017

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

289036

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

0

High-throughput

0.458

High

289037

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.458

High

288914

ANM2
Protein arginine N-methyltransferase 2

1

3

High-throughput

0.445

High

288915

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.445

High

288916

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

High-throughput

0.445

High

288962

PKHA7
Pleckstrin homology domain-containing family A member 7

1

10

High-throughput

0.445

High

289035

ATD3A
ATPase family AAA domain-containing protein 3A

1

9

High-throughput

0.445

High

227281

SPOP
Speckle-type POZ protein

1

1

High-throughput

0.437

High

288875

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.437

High

288877

RECQ4
ATP-dependent DNA helicase Q4

1

6

High-throughput

0.437

High

288878

HEXI1
Protein HEXIM1

1

1

High-throughput

0.437

High

288887

MYCN
N-myc proto-oncogene protein

1

7

High-throughput

0.437

High

288895

TFE2
Transcription factor E2-alpha

1

1

High-throughput

0.437

High

288960

Q6ICH2
single-stranded DNA cytosine deaminase

1

2

High-throughput

0.437

High

288967

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.437

High

289020

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.437

High

289023

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.437

High

289060

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.437

High

288876

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

0

High-throughput

0.426

High

289018

P63
Tumor protein 63

1

3

Small-scale

0.417

High

73363

B2CML4
single-stranded DNA cytosine deaminase

1

2

High-throughput

0.407

High

288935

SLC31
Amino acid transporter heavy chain SLC3A1

1

1

High-throughput

0.407

High

288896

TSHR
Thyrotropin receptor

1

0

High-throughput

0.279

Low

288929

HTRA4
Serine protease HTRA4

1

0

High-throughput

0.279

Low

289061

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.279

Low

288882

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.268

Low

288971

ZER1
Protein zer-1 homolog

1

0

High-throughput

0.249

Low

289013

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

289032

TMPS4
Transmembrane protease serine 4

1

0

High-throughput

0.249

Low

289039

DJC28
DnaJ homolog subfamily C member 28

1

0

High-throughput

0.249

Low

288906

EAA1
Excitatory amino acid transporter 1

1

0

High-throughput

0.232

Low

289042

GRHL1
Grainyhead-like protein 1 homolog

1

0

High-throughput

0.232

Low

289049

LORF1
LINE-1 retrotransposable element ORF1 protein

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025