HitPredict

Interactor 1: G5EG22 (G5EG22)
Methylosome subunit pICln
Gene: icln-1

Interactor 2: SMD1 (Q10013)
Probable small nuclear ribonucleoprotein Sm D1 (Sm-D1) (snRNP core protein D1)
Gene: snr-3

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.40	1.00	0.637

Property	Details
Experiments	19123269
Identification Methods	two hybrid array, two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LSM~Voldacs
Common GO terms	GO:0000387 - spliceosomal snRNP assembly GO:0005829 - cytosol GO:0034715 - pICln-Sm protein complex
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 225 Ce			1 126
+	Ce
		107977 G5EG22_CAEEL (1-225): 7.29e-77: 232: 100.00		SMD3_CAEEL (2-121): 2.85e-35: 120: 31.41
+	Ce
		107955 G5EFZ5_CAEEL (1-225): 1.44e-70: 215: 90.67		SMD3_CAEEL (2-121): 2.85e-35: 120: 31.41
+	Ce
		107954 G5EFZ5_CAEEL (1-225): 1.44e-70: 215: 90.67		SMD1_CAEEL (1-121): 4.68e-28: 101: 100.00
+	Hs
		867409 ICLN_HUMAN (2-213): 9.52e-56: 179: 28.70		SMD1_HUMAN (1-96): 6.27e-35: 118: 76.04
+	Hs
		867495 ICLN_HUMAN (2-213): 9.52e-56: 179: 28.70		LSM4_HUMAN (1-89): 1.45e-34: 118: 25.56
+	Hs
		867411 ICLN_HUMAN (2-213): 9.52e-56: 179: 28.70		SMD3_HUMAN (2-105): 4.14e-33: 113: 23.08
+	Hs
		867492 ICLN_HUMAN (2-213): 9.52e-56: 179: 28.70		LSM2_HUMAN (1-94): 2.09e-33: 113: 34.38
+	Dm
		55530 ICLN_DROME (1-212): 8.17e-54: 173: 16.81		Q9VTW6_DROME (1-90): 1.08e-33: 114: 35.87
+	Hs
		867458 ICLN_HUMAN (2-213): 9.52e-56: 179: 28.70		LSM10_HUMAN (3-100): 3.51e-30: 106: 27.55
+	Hs
		867405 ICLN_HUMAN (2-213): 9.52e-56: 179: 28.70		RUXF_HUMAN (3-69): 2.72e-27: 98.1: 29.85
+	Sp
		142871 ICLN_SCHPO (33-192): 1.59e-35: 126: 23.60		SMD1_SCHPO (1-95): 3.82e-35: 118: 68.42
+	Sp
		142881 ICLN_SCHPO (33-192): 1.59e-35: 126: 23.60		SMD3_SCHPO (2-81): 3.96e-29: 103: 28.75