HitPredict

Interactor 1: EXT1 (Q16394)
Exostosin-1 (EC 2.4.1.225) (Exostosin glycosyltransferase 1) (Heparan sulfate co-polymerase subunit EXT1) (Multiple exostoses protein 1) (N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase)
Gene: EXT1

Interactor 2: S39A5 (Q6ZMH5)
Zinc transporter ZIP5 (Solute carrier family 39 member 5) (Zrt- and Irt-like protein 5) (ZIP-5)
Gene: SLC39A5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030509 - BMP signaling pathway
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 746 Hs			1 540
+	Hs
		217178 EXTL3_HUMAN (72-739): 0: 667: 27.17		S39A5_HUMAN (1-540): 4.37e-162: 473: 100.00
+	Hs
		217175 EXTL3_HUMAN (72-739): 0: 667: 27.17		S39A4_HUMAN (155-533): 4.68e-78: 259: 33.51
+	Hs
		1168301 EXTL2_HUMAN (471-724): 8.69e-95: 299: 28.73		S39A5_HUMAN (1-540): 4.37e-162: 473: 100.00
+	Hs
		1319443 EXTL2_HUMAN (471-724): 8.69e-95: 299: 28.73		S39A8_HUMAN (153-533): 4.9e-87: 278: 26.77
+	Hs
		1160209 EXTL2_HUMAN (471-724): 8.69e-95: 299: 28.73		S39A4_HUMAN (155-533): 4.68e-78: 259: 33.51