HitPredict

Interactor 1: PKN1 (Q16512)
Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)
Gene: PKN1

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 942 Hs			1 779
+	Hs
		1082035 PKN2_HUMAN (6-942): 0: 1018: 56.41		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1160283 PKN3_HUMAN (36-939): 0: 867: 49.84		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1148919 PKN3_HUMAN (36-939): 0: 867: 49.84		CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81
+	Hs
		408682 KPCB_HUMAN (462-940): 3.02e-167: 505: 36.12		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		566481 KPCA_HUMAN (452-940): 6.34e-166: 502: 36.13		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		623884 KPCL_HUMAN (571-940): 3.09e-152: 467: 44.36		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		682210 AKT2_HUMAN (564-940): 4.13e-154: 464: 40.42		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		682023 AKT1_HUMAN (587-941): 7.64e-153: 461: 43.06		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		981062 KPCT_HUMAN (560-941): 6.45e-149: 459: 45.22		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		984534 KPCD_HUMAN (608-938): 7.48e-103: 337: 50.30		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		408612 KPCB_HUMAN (462-940): 3.02e-167: 505: 36.12		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		566377 KPCA_HUMAN (452-940): 6.34e-166: 502: 36.13		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		681831 AKT1_HUMAN (587-941): 7.64e-153: 461: 43.06		GAB1_HUMAN (52-611): 6.48e-53: 197: 13.92
+	Mm
		930572 KPCG_MOUSE (462-940): 1.25e-153: 471: 37.77		CNKR2_MOUSE (1-468): 7.51e-48: 185: 14.40
+	Hs
		397159 KPCG_HUMAN (462-940): 3.1e-154: 472: 37.77		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Rn
		1144020 AKT3_RAT (578-941): 2.89e-151: 457: 40.54		CAPS1_RAT (11-428): 1.59e-46: 181: 10.23
+	Hs
		969077 KPCE_HUMAN (484-937): 3.81e-147: 455: 35.41		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		984488 KPCD_HUMAN (608-938): 7.48e-103: 337: 50.30		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		1071703 KS6A2_HUMAN (513-922): 7.5e-95: 317: 24.30		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61