HitPredict

Interactor 1: DDB1 (Q16531)
DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)
Gene: DDB1

Interactor 2: HIF1A (Q16665)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8)
Gene: HIF1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27320910
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0032991 - protein-containing complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1140 Hs			1 826
+	Mm
		1112313 DDB1_MOUSE (1-1140): 0: 1422: 99.65		BMAL1_MOUSE (7-505): 2.8e-116: 368: 20.92
+	Hs
		728929 DDB1_HUMAN (1-1140): 0: 1424: 100.00		AHR_HUMAN (7-745): 4.08e-113: 366: 15.97
+	Hs
		649121 DDB1_HUMAN (1-1140): 0: 1424: 100.00		ARNT_HUMAN (7-652): 5.14e-103: 338: 17.06
+	Mm
		139866 DDB1_MOUSE (1-1140): 0: 1422: 99.65		CLOCK_MOUSE (2-704): 2.25e-102: 338: 17.88
+	Hs
		728921 SF3B3_HUMAN (3-1126): 0: 1102: 21.33		AHR_HUMAN (7-745): 4.08e-113: 366: 15.97
+	Hs
		1014135 CPSF1_HUMAN (4-527): 4.39e-117: 397: 15.87		HIF1A_HUMAN (1-826): 0: 741: 100.00
+	Hs
		1014130 CPSF1_HUMAN (4-527): 4.39e-117: 397: 15.87		NCOA2_HUMAN (1-747): 3.97e-109: 367: 15.62