HitPredict

Interactor 1: DDB1 (Q16531)
DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)
Gene: DDB1

Interactor 2: DDB2 (Q92466)
DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2)
Gene: DDB2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.995

The method score is based on:

Property Details
Experiments 16949367, 26186194, 24249678, 26410533, 16751180, 27203177, 28514442, 28035050, 17392787, 29262658, 30923324, 12050362, 32985517, 33961781, 18593899, 35938868, 35813480, 37689310, 16473935, 17041588 and 20 others

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Identification Methods affinity chromatography technology, pull down, unspecified method, proximity labelling technology, x-ray crystallography, biochemical, transmission electron microscopy, anti bait coimmunoprecipitation, dynamic light scattering, anti tag coimmunoprecipitation and 1 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CPSF_A~WD40, MMS1_N~WD40
Common GO terms GO:0003677 - DNA binding
GO:0003684 - damaged DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair
and 9 others

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Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1140
Hs

1 427
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Last updated: 15 Jul 2024