Protein: ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (VLCAD) (EC 1.3.8.9)

Gene: ACADV, ACADVL
Organism: Homo sapiens
Interactions: 133
UniProt ID: P49748

Gene Ontology (top 5):
GO:0000062 - fatty-acyl-CoA binding
GO:0001659 - temperature homeostasis
GO:0003995 - acyl-CoA dehydrogenase activity
GO:0004466 - long-chain fatty acyl-CoA dehydrogenase activity
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

888503

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

2

17

Small-scale

0.712

High

888519

SURF1
Surfeit locus protein 1

4

1

High-throughput

0.687

High

888532

HIBCH
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial

3

7

High-throughput

0.667

High

888548

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

3

3

High-throughput

0.667

High

888551

DHRS4
Dehydrogenase/reductase SDR family member 4

3

1

High-throughput

0.662

High

777600

HMGCL
Hydroxymethylglutaryl-CoA lyase, mitochondrial

3

3

High-throughput

0.656

High

668529

APC
Adenomatous polyposis coli protein

3

0

High-throughput

0.634

High

888574

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

2

1

High-throughput

0.628

High

888535

CLASR
CLK4-associating serine/arginine rich protein

2

0

High-throughput

0.602

High

888568

SIR3
NAD-dependent protein deacetylase sirtuin-3, mitochondrial

2

5

Small-scale

0.595

High

241087

PRKN
E3 ubiquitin-protein ligase parkin

2

8

High-throughput

0.584

High

279701

CISY
Citrate synthase, mitochondrial

2

6

High-throughput

0.584

High

888523

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

4

High-throughput

0.584

High

888531

MRM1
rRNA methyltransferase 1, mitochondrial

2

3

High-throughput

0.584

High

888525

TAF1B
TATA box-binding protein-associated factor RNA polymerase I subunit B

2

0

High-throughput

0.580

High

702325

ELK4
ETS domain-containing protein Elk-4

2

1

High-throughput

0.571

High

888529

MYOME
Myomegalin

2

3

High-throughput

0.558

High

583499

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

1

High-throughput

0.536

High

888511

CKAP5
Cytoskeleton-associated protein 5

1

2

High-throughput

0.536

High

888512

ICT1
Large ribosomal subunit protein mL62

1

1

High-throughput

0.536

High

888553

GNL3
Guanine nucleotide-binding protein-like 3

1

1

High-throughput

0.536

High

105572

APRIO
Alternative prion protein

2

1

High-throughput

0.533

High

635694

RASA1
Ras GTPase-activating protein 1

2

2

High-throughput

0.521

High

122735

KIF2A
Kinesin-like protein KIF2A

1

0

High-throughput

0.513

High

388167

GLPA
Glycophorin-A

1

0

High-throughput

0.513

High

888556

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.513

High

222360

TSN6
Tetraspanin-6

1

1

High-throughput

0.489

High

563423

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.489

High

602763

AATC
Aspartate aminotransferase, cytoplasmic

1

3

High-throughput

0.489

High

888539

IL31R
Interleukin-31 receptor subunit alpha

1

4

High-throughput

0.489

High

888571

KLH11
Kelch-like protein 11

1

1

High-throughput

0.489

High

155923

SOCS3
Suppressor of cytokine signaling 3

1

1

Small-scale

0.481

High

476602

RSSA
Small ribosomal subunit protein uS2

1

1

High-throughput

0.481

High

137677

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

1

High-throughput

0.479

High

400484

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.479

High

403913

GCR
Glucocorticoid receptor

1

4

Small-scale

0.479

High

411579

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.479

High

416001

CP1A1
Cytochrome P450 1A1

1

1

High-throughput

0.479

High

487086

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.479

High

532453

CH60
60 kDa heat shock protein, mitochondrial

1

4

High-throughput

0.479

High

588198

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

694921

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

767691

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.479

High

828708

MDHM
Malate dehydrogenase, mitochondrial

1

7

High-throughput

0.479

High

851845

EFTS
Elongation factor Ts, mitochondrial

1

4

High-throughput

0.479

High

878774

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

888506

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

888508

KIF23
Kinesin-like protein KIF23

1

2

High-throughput

0.479

High

888509

MPPA
Mitochondrial-processing peptidase subunit alpha

1

8

High-throughput

0.479

High

888515

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

888517

PDK1
[Pyruvate dehydrogenase

1

6

High-throughput

0.479

High

888520

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

888521

E2F4
Transcription factor E2F4

1

2

High-throughput

0.479

High

888528

SYAM
Alanine--tRNA ligase, mitochondrial

1

3

High-throughput

0.479

High

888541

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

888542

HDAC2
Histone deacetylase 2

1

3

High-throughput

0.479

High

888543

MCUR1
Mitochondrial calcium uniporter regulator 1

1

4

High-throughput

0.479

High

888545

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

2

High-throughput

0.479

High

888546

TEFM
Transcription elongation factor, mitochondrial

1

1

High-throughput

0.479

High

888547

IMP2L
Mitochondrial inner membrane protease subunit 2

1

6

High-throughput

0.479

High

888552

TMM70
Transmembrane protein 70, mitochondrial

1

1

High-throughput

0.479

High

888557

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

888558

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

4

High-throughput

0.479

High

888560

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

1

Small-scale

0.479

High

888561

MET17
Ribosome assembly protein METTL17, mitochondrial

1

4

High-throughput

0.479

High

888563

ECT2
Protein ECT2

1

1

High-throughput

0.479

High

888565

ANLN
Anillin

1

1

High-throughput

0.479

High

888570

DJC11
DnaJ homolog subfamily C member 11

1

3

High-throughput

0.479

High

888572

TLS1
Splicing factor C9orf78

1

3

High-throughput

0.479

High

888575

MRES1
Mitochondrial transcription rescue factor 1

1

2

High-throughput

0.479

High

888576

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

6

High-throughput

0.479

High

888577

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

888581

ARI1
E3 ubiquitin-protein ligase ARIH1

1

6

High-throughput

0.479

High

274991

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

887839

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

888522

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

888526

OXLD1
Oxidoreductase-like domain-containing protein 1

1

0

High-throughput

0.458

High

888559

IPYR2
Inorganic pyrophosphatase 2, mitochondrial

1

0

High-throughput

0.458

High

888580

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.458

High

72921

B1AK13
Hydroxymethylglutaryl-CoA lyase, mitochondrial

1

3

High-throughput

0.445

High

888510

RM49
Large ribosomal subunit protein mL49

1

2

High-throughput

0.445

High

888513

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

5

Small-scale

0.445

High

888554

TR61B
tRNA

1

3

High-throughput

0.445

High

888569

DDX28
Probable ATP-dependent RNA helicase DDX28

1

1

High-throughput

0.445

High

888579

PA2G4
Proliferation-associated protein 2G4

1

2

Small-scale

0.445

High

888582

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

5

High-throughput

0.445

High

888566

GEPH
Gephyrin [Includes: Molybdopterin adenylyltransferase

1

1

High-throughput

0.439

High

158956

GP171
G-protein coupled receptor 171

1

4

High-throughput

0.437

High

353108

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

550180

PABP1
Polyadenylate-binding protein 1

1

1

High-throughput

0.437

High

888514

EMC2
ER membrane protein complex subunit 2

1

1

High-throughput

0.437

High

888516

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.437

High

888527

EMC4
ER membrane protein complex subunit 4

1

1

High-throughput

0.437

High

888534

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

888538

EMC1
ER membrane protein complex subunit 1

1

1

High-throughput

0.437

High

888562

DJC18
DnaJ homolog subfamily C member 18

1

2

High-throughput

0.437

High

888573

ITSN2
Intersectin-2

1

2

High-throughput

0.437

High

443266

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.426

High

529344

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

807316

IF4A3
Eukaryotic initiation factor 4A-III

1

0

Small-scale

0.426

High

362972

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.407

High

888504

MAP2
Methionine aminopeptidase 2

1

2

Small-scale

0.407

High

888530

A16L1
Autophagy-related protein 16-1

1

3

High-throughput

0.407

High

888536

TTC9C
Tetratricopeptide repeat protein 9C

1

1

High-throughput

0.407

High

888537

CD177
CD177 antigen

1

2

Small-scale

0.407

High

888540

S22AH
Solute carrier family 22 member 17

1

1

High-throughput

0.407

High

888555

S12A9
Solute carrier family 12 member 9

1

3

High-throughput

0.407

High

888567

ITM2C
Integral membrane protein 2C

1

3

High-throughput

0.407

High

338683

VNN2
Pantetheine hydrolase VNN2

2

0

High-throughput

0.328

High

376982

ANF
Natriuretic peptides A

2

0

High-throughput

0.328

High

888564

SHCAF
SIN3-HDAC complex-associated factor

2

0

High-throughput

0.328

High

888533

TRAT1
T-cell receptor-associated transmembrane adapter 1

2

0

High-throughput

0.313

High

134441

EF2K
Eukaryotic elongation factor 2 kinase

1

0

Small-scale

0.279

Low

325306

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

391587

FRIH
Ferritin heavy chain

1

0

High-throughput

0.279

Low

876295

PTSS1
Phosphatidylserine synthase 1

1

0

High-throughput

0.279

Low

888507

DSCR6
Protein ripply3

1

0

High-throughput

0.279

Low

888524

SGSM1
Small G protein signaling modulator 1

1

0

High-throughput

0.279

Low

555956

CADH1
Cadherin-1

1

0

Small-scale

0.269

Low

74208

CF97D
Sperm axonemal maintenance protein CFAP97D1

1

0

High-throughput

0.249

Low

629660

BTF3
Transcription factor BTF3

1

0

High-throughput

0.249

Low

849304

RANG
Ran-specific GTPase-activating protein

1

0

High-throughput

0.249

Low

888544

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.249

Low

888549

LARP6
La-related protein 6

1

0

High-throughput

0.249

Low

888550

DCNL5
DCN1-like protein 5

1

0

Small-scale

0.249

Low

888578

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

220684

DENR
Density-regulated protein

1

0

Small-scale

0.232

Low

261129

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low

389986

ALBU
Albumin

1

0

Small-scale

0.232

Low

633418

ANPRB
Atrial natriuretic peptide receptor 2

1

0

High-throughput

0.232

Low

888505

ANAG
Alpha-N-acetylglucosaminidase

1

0

High-throughput

0.232

Low

888518

SC23B
Protein transport protein Sec23B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025