Interactor 1: DDB1 (Q16531)
DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)
Gene: DDB1

Interactor 2: DYRK2 (Q92630)
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)
Gene: DYRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.875

The method score is based on:

Property Details
Experiments 28242748, 32707033, 19287380
Identification Methods affinity chromatography technology, proximity labelling technology, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CPSF_A~Pkinase, MMS1_N~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006974 - DNA damage response
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1140
Hs

1 601
+ Hs
+ Dm
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024