HitPredict

Interactor 1: DDB1 (Q16531)
DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)
Gene: DDB1

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25499913, 17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006974 - DNA damage response GO:0032991 - protein-containing complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1140 Hs			1 522
+	Hs
		1052672 DDB1_HUMAN (1-1140): 0: 1424: 100.00		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		301825 SF3B3_HUMAN (3-1126): 0: 1102: 21.33		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		1073031 SF3B3_HUMAN (3-1126): 0: 1102: 21.33		TRAF7_HUMAN (60-208): 5.13e-18: 89.5: 23.26