HitPredict

Interactor 1: SNPC1 (Q16533)
snRNA-activating protein complex subunit 1 (SNAPc subunit 1) (Proximal sequence element-binding transcription factor subunit gamma) (PSE-binding factor subunit gamma) (PTF subunit gamma) (Small nuclear RNA-activating complex polypeptide 1) (snRNA-activating protein complex 43 kDa subunit) (SNAPc 43 kDa subunit)
Gene: SNAPC1

Interactor 2: SNPC4 (Q5SXM2)
snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha) (snRNA-activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit)
Gene: SNAPC4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.720

The method score is based on:

Property Details
Experiments 11056176, 26186194, 28514442, 33961781, 36369505
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000995 - RNA polymerase III general transcription initiation factor activity
GO:0005654 - nucleoplasm
GO:0016251 - RNA polymerase II general transcription initiation factor activity
GO:0019185 - snRNA-activating protein complex
GO:0042795 - snRNA transcription by RNA polymerase II
and 1 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 368
Hs

1 1469
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024