Interactor 1: B2LA1 (Q16548)
Bcl-2-related protein A1 (Bcl-2-like protein 5) (Bcl2-L-5) (Hemopoietic-specific early response protein) (Protein BFL-1) (Protein GRS)
Gene: BCL2A1

Interactor 2: BBC3 (Q9BXH1)
Bcl-2-binding component 3, isoforms 1/2 (JFY-1) (p53 up-regulated modulator of apoptosis)
Gene: BBC3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 16697956
Identification Methods fluorescence polarization spectroscopy
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~PUMA
Common GO terms GO:0001836 - release of cytochrome c from mitochondria
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 175
Hs

1 193
+ Mm
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+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024