Protein: ST14
Suppressor of tumorigenicity 14 protein (EC 3.4.21.109) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease 14) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein)

Gene: ST14
Organism: Homo sapiens
Interactions: 203
UniProt ID: Q9Y5Y6

Gene Ontology (top 5):
GO:0001843 - neural tube closure
GO:0004252 - serine-type endopeptidase activity
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1047790

NOTC2
Neurogenic locus notch homolog protein 2

2

11

High-throughput

0.817

High

212513

SPIT2
Kunitz-type protease inhibitor 2

1

15

High-throughput

0.691

High

249070

NRP2
Neuropilin-2

1

20

High-throughput

0.691

High

269717

PLXA2
Plexin-A2

1

15

High-throughput

0.691

High

296391

ATRN
Attractin

1

15

High-throughput

0.691

High

317596

SLIT2
Slit homolog 2 protein

1

11

High-throughput

0.691

High

366558

TPA
Tissue-type plasminogen activator

1

17

High-throughput

0.691

High

376568

LDLR
Low-density lipoprotein receptor

1

8

High-throughput

0.691

High

423546

A4
Amyloid-beta precursor protein

1

18

High-throughput

0.691

High

450193

GDN
Glia-derived nexin

1

20

High-throughput

0.691

High

467043

DAF
Complement decay-accelerating factor

1

11

High-throughput

0.691

High

472155

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.691

High

521057

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

12

High-throughput

0.691

High

565114

CSPG2
Versican core protein

1

11

High-throughput

0.691

High

599143

CBPE
Carboxypeptidase E

1

6

High-throughput

0.691

High

607440

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

12

High-throughput

0.691

High

654574

FBLN1
Fibulin-1

1

16

High-throughput

0.691

High

772301

FBN1
Fibrillin-1 [Cleaved into: Asprosin]

1

11

High-throughput

0.691

High

787843

PEDF
Pigment epithelium-derived factor

1

20

High-throughput

0.691

High

1022528

VLDLR
Very low-density lipoprotein receptor

1

8

High-throughput

0.691

High

1055379

APLP2
Amyloid beta precursor like protein 2

1

15

High-throughput

0.691

High

1064086

MFGM
Lactadherin

1

16

High-throughput

0.691

High

1126064

GAS6
Growth arrest-specific protein 6

1

20

High-throughput

0.691

High

1249919

CREL2
Protein disulfide isomerase CRELD2

1

12

High-throughput

0.691

High

1291967

LRP11
Low-density lipoprotein receptor-related protein 11

1

6

High-throughput

0.691

High

1352115

ATS15
A disintegrin and metalloproteinase with thrombospondin motifs 15

1

11

High-throughput

0.691

High

1366798

NECT2
Nectin-2

1

15

High-throughput

0.691

High

1376973

HMR1
Major histocompatibility complex class I-related protein 1

1

12

High-throughput

0.691

High

1380615

IGSF8
Immunoglobulin superfamily member 8

1

5

High-throughput

0.691

High

1390511

LIGO1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

1

12

High-throughput

0.691

High

1402435

HPLN3
Hyaluronan and proteoglycan link protein 3

1

4

High-throughput

0.691

High

1405357

NEUS
Neuroserpin

1

20

High-throughput

0.691

High

1408467

SEM3C
Semaphorin-3C

1

4

High-throughput

0.691

High

1431739

SEM6A
Semaphorin-6A

1

4

High-throughput

0.691

High

1432134

KLK15
Kallikrein-15

1

17

High-throughput

0.691

High

1433632

SMOC1
SPARC-related modular calcium-binding protein 1

1

2

High-throughput

0.691

High

1438806

SPON1
Spondin-1

1

5

High-throughput

0.691

High

1453627

CRIM1
Cysteine-rich motor neuron 1 protein

1

13

High-throughput

0.691

High

1458874

FBLN5
Fibulin-5

1

11

High-throughput

0.691

High

1459974

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

11

High-throughput

0.691

High

1460482

BTNL2
Butyrophilin-like protein 2

1

9

High-throughput

0.691

High

1461972

NOTC3
Neurogenic locus notch homolog protein 3

1

9

High-throughput

0.691

High

1490437

JAG2
Protein jagged-2

1

9

High-throughput

0.691

High

1491782

TLL2
Tolloid-like protein 2

1

19

High-throughput

0.691

High

1448096

PDGFC
Platelet-derived growth factor C

1

19

Small-scale

0.647

High

215736

COCH
Cochlin

1

7

High-throughput

0.618

High

269892

IGSF3
Immunoglobulin superfamily member 3

1

5

High-throughput

0.618

High

772353

FBN2
Fibrillin-2 [Cleaved into: Placensin]

1

12

High-throughput

0.618

High

1335230

NETO2
Neuropilin and tolloid-like protein 2

1

17

High-throughput

0.618

High

1459919

EGFL7
Epidermal growth factor-like protein 7

1

14

High-throughput

0.618

High

1461337

PCOC2
Procollagen C-endopeptidase enhancer 2

1

19

High-throughput

0.618

High

211961

SPIT1
Kunitz-type protease inhibitor 1

1

18

Small-scale

0.618

High

369227

ISK1
Serine protease inhibitor Kazal-type 1

1

0

High-throughput

0.578

High

689930

HGFL
Hepatocyte growth factor-like protein

1

16

Small-scale

0.575

High

1156931

IBP7
Insulin-like growth factor-binding protein 7

1

4

Small-scale

0.575

High

631596

RAB5A
Ras-related protein Rab-5A

2

4

High-throughput

0.571

High

355054

CHK2
Serine/threonine-protein kinase Chk2

1

3

High-throughput

0.541

High

376936

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

7

High-throughput

0.541

High

728503

AKT1
RAC-alpha serine/threonine-protein kinase

1

5

High-throughput

0.541

High

161111

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

18

High-throughput

0.536

High

261678

CATL2
Cathepsin L2

1

3

High-throughput

0.536

High

283728

GPC4
Glypican-4

1

11

High-throughput

0.536

High

302271

STC2
Stanniocalcin-2

1

5

High-throughput

0.536

High

341382

ECEL1
Endothelin-converting enzyme-like 1

1

4

High-throughput

0.536

High

462941

LAMB1
Laminin subunit beta-1

1

9

High-throughput

0.536

High

473735

ITA5
Integrin alpha-5

1

11

High-throughput

0.536

High

506918

CFC1
Cryptic protein

1

1

High-throughput

0.536

High

548156

PSPC
Surfactant protein C

1

4

High-throughput

0.536

High

548653

MPRI
Cation-independent mannose-6-phosphate receptor

1

7

High-throughput

0.536

High

582403

B4GT1
Beta-1,4-galactosyltransferase 1

1

9

High-throughput

0.536

High

611637

IBP2
Insulin-like growth factor-binding protein 2

1

5

High-throughput

0.536

High

655030

ITA6
Integrin alpha-6

1

11

High-throughput

0.536

High

774817

TIMP3
Metalloproteinase inhibitor 3

1

5

High-throughput

0.536

High

813268

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

3

High-throughput

0.536

High

820549

IL6RB
Interleukin-6 receptor subunit beta

1

6

High-throughput

0.536

High

833489

WNT5A
Protein Wnt-5a

1

3

High-throughput

0.536

High

835783

KPCI
Protein kinase C iota type

1

5

High-throughput

0.536

High

889939

VEGFB
Vascular endothelial growth factor B

1

1

High-throughput

0.536

High

906379

GPC3
Glypican-3

1

11

High-throughput

0.536

High

914565

EFNA5
Ephrin-A5

1

4

High-throughput

0.536

High

932024

EPHB4
Ephrin type-B receptor 4

1

17

High-throughput

0.536

High

942171

WNT3A
Protein Wnt-3a

1

3

High-throughput

0.536

High

945922

INHBE
Inhibin beta E chain

1

7

High-throughput

0.536

High

1038213

GCNT1
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

1

2

High-throughput

0.536

High

1041652

TGBR3
Transforming growth factor beta receptor type 3

1

2

High-throughput

0.536

High

1102781

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

7

High-throughput

0.536

High

1105795

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

17

High-throughput

0.536

High

1106185

TUSC3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3

1

1

High-throughput

0.536

High

1108331

SQSTM
Sequestosome-1

1

2

High-throughput

0.536

High

1248601

LYPD4
Ly6/PLAUR domain-containing protein 4

1

1

High-throughput

0.536

High

1293322

LSR
Lipolysis-stimulated lipoprotein receptor

1

2

High-throughput

0.536

High

1311068

SULF1
Extracellular sulfatase Sulf-1

1

7

High-throughput

0.536

High

1316131

K319L
Dyslexia-associated protein KIAA0319-like protein

1

5

High-throughput

0.536

High

1323092

GPC2
Glypican-2 [Cleaved into: Secreted glypican-2]

1

11

High-throughput

0.536

High

1363170

CLC2B
C-type lectin domain family 2 member B

1

5

High-throughput

0.536

High

1363582

FAM3C
Protein FAM3C

1

2

High-throughput

0.536

High

1369119

PCSK5
Proprotein convertase subtilisin/kexin type 5

1

8

High-throughput

0.536

High

1370040

GSLG1
Golgi apparatus protein 1

1

1

High-throughput

0.536

High

1382099

T106A
Transmembrane protein 106A

1

6

High-throughput

0.536

High

1390909

ASIC4
Acid-sensing ion channel 4

1

1

High-throughput

0.536

High

1407382

TM9S2
Transmembrane 9 superfamily member 2

1

7

High-throughput

0.536

High

1416344

CHID1
Chitinase domain-containing protein 1

1

1

High-throughput

0.536

High

1420102

ULBP3
UL16-binding protein 3

1

14

High-throughput

0.536

High

1432502

CRLD1
Cysteine-rich secretory protein LCCL domain-containing 1

1

6

High-throughput

0.536

High

1439732

JPH1
Junctophilin-1

1

3

High-throughput

0.536

High

1458488

P2RX2
P2X purinoceptor 2

1

2

High-throughput

0.536

High

1460473

LCAP
Leucyl-cystinyl aminopeptidase

1

3

High-throughput

0.536

High

1460877

FBX2
F-box only protein 2

1

2

High-throughput

0.536

High

1461076

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

1

17

High-throughput

0.536

High

1491777

BACE2
Beta-secretase 2

1

3

High-throughput

0.536

High

1491778

GPC6
Glypican-6 [Cleaved into: Secreted glypican-6]

1

11

High-throughput

0.536

High

192040

RGS16
Regulator of G-protein signaling 16

1

0

High-throughput

0.518

High

668768

APC
Adenomatous polyposis coli protein

1

0

High-throughput

0.518

High

766987

PHB1
Prohibitin 1

1

0

High-throughput

0.518

High

1132474

CASP8
Caspase-8

1

0

High-throughput

0.518

High

441459

CHLE
Cholinesterase

1

0

High-throughput

0.513

High

635669

ASPG
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase

1

0

High-throughput

0.513

High

757364

RNAS4
Ribonuclease 4

1

0

High-throughput

0.513

High

933253

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.513

High

1337017

DIK2A
Divergent protein kinase domain 2A

1

0

High-throughput

0.513

High

1386247

ASTRA
Protein Aster-A

1

0

High-throughput

0.513

High

843004

CDN2C
Cyclin-dependent kinase 4 inhibitor C

1

1

High-throughput

0.494

High

1056009

RAD51
DNA repair protein RAD51 homolog 1

1

1

High-throughput

0.494

High

1154486

STK11
Serine/threonine-protein kinase STK11

1

1

High-throughput

0.494

High

1068347

AHNK
Neuroblast differentiation-associated protein AHNAK

1

0

High-throughput

0.493

High

160782

TOR1A
Torsin-1A

1

14

High-throughput

0.489

High

191471

SIA8E
Alpha-2,8-sialyltransferase 8E

1

6

High-throughput

0.489

High

261571

B4GT2
Beta-1,4-galactosyltransferase 2

1

9

High-throughput

0.489

High

340714

NET1
Netrin-1

1

5

High-throughput

0.489

High

568026

PRG2
Bone marrow proteoglycan

1

1

High-throughput

0.489

High

687133

MGAT1
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

4

High-throughput

0.489

High

689911

FKBP2
Peptidyl-prolyl cis-trans isomerase FKBP2

1

4

High-throughput

0.489

High

755434

MA1A1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

1

7

High-throughput

0.489

High

880760

LMAN1
Protein ERGIC-53

1

6

High-throughput

0.489

High

914857

NDST1
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

1

1

High-throughput

0.489

High

997213

TBA4A
Tubulin alpha-4A chain

1

8

High-throughput

0.489

High

999568

NOMO3
BOS complex subunit NOMO3

1

5

High-throughput

0.489

High

1083090

MGAT2
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

1

High-throughput

0.489

High

1083166

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

14

High-throughput

0.489

High

1126283

GALT3
Polypeptide N-acetylgalactosaminyltransferase 3

1

14

High-throughput

0.489

High

1127953

PDIA5
Protein disulfide-isomerase A5

1

4

High-throughput

0.489

High

1143709

NOMO1
BOS complex subunit NOMO1

1

5

High-throughput

0.489

High

1162164

MA2A1
Alpha-mannosidase 2

1

1

High-throughput

0.489

High

1163345

LAMA3
Laminin subunit alpha-3

1

10

High-throughput

0.489

High

1164367

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

3

High-throughput

0.489

High

1187817

UD3A2
UDP-glucuronosyltransferase 3A2

1

3

High-throughput

0.489

High

1194729

GXLT1
Glucoside xylosyltransferase 1

1

3

High-throughput

0.489

High

1204911

MKS3
Meckelin

1

2

High-throughput

0.489

High

1208469

EOGT
EGF domain-specific O-linked N-acetylglucosamine transferase

1

2

High-throughput

0.489

High

1214148

DIK1A
Divergent protein kinase domain 1A

1

2

High-throughput

0.489

High

1228415

SE1L3
Protein sel-1 homolog 3

1

1

High-throughput

0.489

High

1245629

TXD11
Thioredoxin domain-containing protein 11

1

5

High-throughput

0.489

High

1248815

LYZL1
Lysozyme-like protein 1

1

1

High-throughput

0.489

High

1276025

D19L4
Probable C-mannosyltransferase DPY19L4

1

1

High-throughput

0.489

High

1286314

GALT7
N-acetylgalactosaminyltransferase 7

1

14

High-throughput

0.489

High

1288112

OAF
Out at first protein homolog

1

2

High-throughput

0.489

High

1292157

ANR46
Ankyrin repeat domain-containing protein 46

1

3

High-throughput

0.489

High

1294941

ERO1B
ERO1-like protein beta

1

2

High-throughput

0.489

High

1309661

GLBL2
Beta-galactosidase-1-like protein 2

1

2

High-throughput

0.489

High

1325636

GLT16
Polypeptide N-acetylgalactosaminyltransferase 16

1

14

High-throughput

0.489

High

1330453

EMC1
ER membrane protein complex subunit 1

1

3

High-throughput

0.489

High

1333668

PGLT1
Protein O-glucosyltransferase 1

1

3

High-throughput

0.489

High

1335828

GALT6
Polypeptide N-acetylgalactosaminyltransferase 6

1

14

High-throughput

0.489

High

1384615

ESPB1
Epididymal sperm-binding protein 1

1

7

High-throughput

0.489

High

1389757

C1GLC
C1GALT1-specific chaperone 1

1

11

High-throughput

0.489

High

1395684

TM87B
Transmembrane protein 87B

1

2

High-throughput

0.489

High

1398257

H6ST2
Heparan-sulfate 6-O-sulfotransferase 2

1

2

High-throughput

0.489

High

1411658

ADPGK
ADP-dependent glucokinase

1

3

High-throughput

0.489

High

1413918

LMF2
Lipase maturation factor 2

1

2

High-throughput

0.489

High

1414821

ALG12
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase

1

5

High-throughput

0.489

High

1430946

GL8D2
Glycosyltransferase 8 domain-containing protein 2

1

2

High-throughput

0.489

High

1431094

TMX4
Thioredoxin-related transmembrane protein 4

1

12

High-throughput

0.489

High

1433305

TOR3A
Torsin-3A

1

14

High-throughput

0.489

High

1433623

SIA7D
Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase

1

6

High-throughput

0.489

High

1435221

ALG9
Alpha-1,2-mannosyltransferase ALG9

1

5

High-throughput

0.489

High

1437857

UD17
UDP-glucuronosyltransferase 1A7

1

3

High-throughput

0.489

High

1449057

C1GLT
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

1

11

High-throughput

0.489

High

1450260

TM39A
Transmembrane protein 39A

1

1

High-throughput

0.489

High

1453372

E2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3

1

7

High-throughput

0.489

High

1458680

DNJB9
DnaJ homolog subfamily B member 9

1

10

High-throughput

0.489

High

1458795

B4GT7
Beta-1,4-galactosyltransferase 7

1

9

High-throughput

0.489

High

1460900

TM59L
Transmembrane protein 59-like

1

2

High-throughput

0.489

High

1491779

RFNG
Beta-1,3-N-acetylglucosaminyltransferase radical fringe

1

11

High-throughput

0.489

High

1491780

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

1

4

High-throughput

0.489

High

1491781

POMT1
Protein O-mannosyl-transferase 1

1

4

High-throughput

0.489

High

375047

RASH
GTPase HRas

1

4

High-throughput

0.479

High

376152

RASK
GTPase KRas

1

4

High-throughput

0.479

High

1106768

SMAD4
Mothers against decapentaplegic homolog 4

1

2

High-throughput

0.437

High

1324238

TOR2X
Prosalusin

1

14

High-throughput

0.437

High

1207203

TOR2A
Torsin-2A

1

17

High-throughput

0.407

High

66415

LIPT2
Octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial

1

0

High-throughput

0.279

Low

618213

AMD
Peptidyl-glycine alpha-amidating monooxygenase

1

0

High-throughput

0.279

Low

880081

DNSL1
Deoxyribonuclease-1-like 1

1

0

High-throughput

0.279

Low

982045

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.279

Low

1160464

TAZ
Tafazzin

1

0

High-throughput

0.279

Low

1245548

OGFD3
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3

1

0

High-throughput

0.279

Low

1325222

ZN664
Zinc finger protein 664

1

0

High-throughput

0.279

Low

1359166

GLMP
Glycosylated lysosomal membrane protein

1

0

High-throughput

0.279

Low

1412777

FEM1A
Protein fem-1 homolog A

1

0

High-throughput

0.279

Low

1428961

IF5A2
Eukaryotic translation initiation factor 5A-2

1

0

High-throughput

0.279

Low

1438322

PLAC1
Placenta-specific protein 1

1

0

High-throughput

0.279

Low

1447665

ENTP7
Ectonucleoside triphosphate diphosphohydrolase 7

1

0

High-throughput

0.279

Low

1490671

UST
Uronyl 2-sulfotransferase

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025